HitPredict

Interactor 1: LAMB2 (P55268)
Laminin subunit beta-2 (Laminin B1s chain) (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta)
Gene: LAMB2

Interactor 2: EGFL7 (Q9UHF1)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene: EGFL7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0007155 - cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1798 Hs			1 273
+	Hs
		937425 LAMB2_HUMAN (1-1798): 0: 1039: 100.00		NELL1_HUMAN (82-180): 4.1e-26: 109: 36.63
+	Hs
		937395 LAMB2_HUMAN (1-1798): 0: 1039: 100.00		NID2_HUMAN (5-272): 9.09e-22: 96.8: 11.42
+	Hs
		462875 LAMB1_HUMAN (17-1797): 0: 1011: 49.83		NID2_HUMAN (5-272): 9.09e-22: 96.8: 11.42
+	Mm
		1032094 NOTC1_MOUSE (475-1294): 5.38e-63: 241: 13.29		EGFL7_MOUSE (1-272): 1.08e-38: 138: 78.10
+	Mm
		204911 NOTC2_MOUSE (732-1279): 2.17e-35: 150: 13.08		EGFL7_MOUSE (1-272): 1.08e-38: 138: 78.10
+	Hs
		535904 LAMC1_HUMAN (1009-1798): 7.74e-27: 122: 10.59		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Dm
		451718 LAMC1_DROME (894-1798): 4.54e-49: 195: 16.34		NOTCH_DROME (68-172): 2.45e-09: 59.8: 22.32
+	Hs
		572704 LAMC3_HUMAN (894-1774): 2.88e-42: 172: 17.94		NID1_HUMAN (60-271): 1.89e-16: 81: 16.46
+	Mm
		1223430 NOTC3_MOUSE (268-678): 1.69e-24: 114: 15.25		EGFL7_MOUSE (1-272): 1.08e-38: 138: 78.10
+	Hs
		857580 NOTC1_HUMAN (169-684): 1.02e-21: 105: 12.52		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Mm
		384329 LAMC1_MOUSE (953-1792): 2.4e-36: 153: 15.40		NID1_MOUSE (60-206): 1.3e-16: 81.4: 18.07
+	Hs
		535877 LAMC1_HUMAN (1009-1798): 7.74e-27: 122: 10.59		NELL1_HUMAN (82-180): 4.1e-26: 109: 36.63
+	Hs
		535839 LAMC1_HUMAN (1009-1798): 7.74e-27: 122: 10.59		NID2_HUMAN (5-272): 9.09e-22: 96.8: 11.42
+	Hs
		535812 LAMC1_HUMAN (1009-1798): 7.74e-27: 122: 10.59		NID1_HUMAN (60-271): 1.89e-16: 81: 16.46
+	Dm
		95089 NOTCH_DROME (248-656): 6.45e-22: 106: 12.44		E1JHA6_DROME (2-138): 3.41e-13: 71.4: 12.93
+	Hs
		857407 NOTC1_HUMAN (169-684): 1.02e-21: 105: 12.52		JAG1_HUMAN (66-168): 2.85e-10: 62.4: 28.57
+	Dm
		451712 NOTCH_DROME (248-656): 6.45e-22: 106: 12.44		NOTCH_DROME (68-172): 2.45e-09: 59.8: 22.32
+	Dm
		451716 NOTCH_DROME (248-656): 6.45e-22: 106: 12.44		DL_DROME (53-168): 3.56e-09: 59: 25.58
+	Hs
		857370 NOTC1_HUMAN (169-684): 1.02e-21: 105: 12.52		NOTC1_HUMAN (85-183): 3.37e-09: 59.4: 21.57
+	Hs
		857591 NOTC3_HUMAN (248-633): 2.3e-19: 98.1: 12.53		NOTC1_HUMAN (85-183): 3.37e-09: 59.4: 21.57