Interactor 1: IF4A1 (P60842)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: EIF4A1
Interactor 2: PDCD4 (Q53EL6)
Programmed cell death protein 4 (Neoplastic transformation inhibitor protein) (Nuclear antigen H731-like) (Protein 197/15a)
Gene: PDCD4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.977 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33020149, 28514442, 17353931, 33961781, 17053147, 22586265, 18296639, 19204291, unassigned3799, 24413684 |
| Identification Methods | pull down, affinity chromatography technology, surface plasmon resonance, x-ray crystallography, nuclear magnetic resonance, cosedimentation in solution, molecular sieving, isothermal titration calorimetry, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DEAD~MA3, Helicase_C~MA3 |
| Common GO terms | GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 15 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
