HitPredict

Interactor 1: IF4A1 (P60842)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: EIF4A1

Interactor 2: IF4G2 (P78344)
Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (Death-associated protein 5) (DAP-5) (p97)
Gene: EIF4G2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.980

The method score is based on:

Property Details
Experiments 10611228, 28524877, 28514442, 29395067, 33961781, 35271311, 37071682, 39358380, 23478064, 16932749, unassigned3799, 16166382
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, molecular sieving, isothermal titration calorimetry, pull down, anti tag coimmunoprecipitation, nuclear magnetic resonance
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~MA3, DEAD~MIF4G, Helicase_C~MA3, Helicase_C~MIF4G
Common GO terms GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0006413 - translational initiation
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 406
Hs

1 907
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Last updated: 11Aug2025