Interactor 1: IF4G1 (Q04637)
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)
Gene: EIF4G1

Interactor 2: IF4A2 (Q14240)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.956

The method score is based on:

Property Details
Experiments 17353931, 29395067, 24981860, 24768540, 24248602, 38334954, 11408474
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti bait coimmunoprecipitation, pull down, coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~MA3, Helicase_C~MA3, DEAD~MIF4G, Helicase_C~MIF4G
Common GO terms GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006413 - translational initiation
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1599
Hs

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Last updated: 11Aug2025