HitPredict

Interactor 1: E7ERP6 (E7ERP6)
NCK adaptor protein 2
Gene: NCK2

Interactor 2: EFS (O43281)
Embryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3)
Gene: EFS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	26871637
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 83 Hs			1 561
+	Hs
		211975 NCK1_HUMAN (1-76): 3.15e-33: 118: 78.95		EFS_HUMAN (1-561): 3.84e-71: 239: 100.00
+	Hs
		211971 FYN_HUMAN (6-82): 5.04e-28: 106: 30.00		EFS_HUMAN (1-561): 3.84e-71: 239: 100.00
+	Mm
		683103 LYN_MOUSE (3-83): 8.44e-29: 108: 30.12		EFS_MOUSE (1-561): 2.63e-61: 213: 79.50
+	Hs
		593997 NCK1_HUMAN (1-76): 3.15e-33: 118: 78.95		CASL_HUMAN (6-336): 1.95e-31: 131: 24.93
+	Hs
		463518 LYN_HUMAN (3-83): 2.23e-28: 107: 28.92		CASL_HUMAN (6-336): 1.95e-31: 131: 24.93
+	Hs
		319045 LYN_HUMAN (3-83): 2.23e-28: 107: 28.92		K0754_HUMAN (29-462): 1.5e-30: 129: 11.01
+	Hs
		594048 NCK1_HUMAN (1-76): 3.15e-33: 118: 78.95		MINK1_HUMAN (48-378): 4.38e-26: 115: 14.67
+	Hs
		593976 NCK1_HUMAN (1-76): 3.15e-33: 118: 78.95		ACK1_HUMAN (9-484): 7.38e-24: 108: 14.85
+	Hs
		463648 LYN_HUMAN (3-83): 2.23e-28: 107: 28.92		MINK1_HUMAN (48-378): 4.38e-26: 115: 14.67
+	Hs
		473406 HCK_HUMAN (2-83): 7.55e-31: 114: 34.52		ACK1_HUMAN (9-484): 7.38e-24: 108: 14.85
+	Hs
		463478 LYN_HUMAN (3-83): 2.23e-28: 107: 28.92		ACK1_HUMAN (9-484): 7.38e-24: 108: 14.85
+	Hs
		215903 NCK1_HUMAN (1-76): 3.15e-33: 118: 78.95		SYNJ1_HUMAN (95-472): 1.19e-18: 92.5: 13.96
+	Hs
		463610 LYN_HUMAN (3-83): 2.23e-28: 107: 28.92		MICA3_HUMAN (61-424): 2.26e-21: 100: 16.45
+	Hs
		593951 NCK1_HUMAN (1-76): 3.15e-33: 118: 78.95		BCAR1_HUMAN (7-431): 3.42e-12: 71.3: 21.40
+	Hs
		473388 HCK_HUMAN (2-83): 7.55e-31: 114: 34.52		BCAR1_HUMAN (7-431): 3.42e-12: 71.3: 21.40
+	Hs
		463425 LYN_HUMAN (3-83): 2.23e-28: 107: 28.92		BCAR1_HUMAN (7-431): 3.42e-12: 71.3: 21.40
+	Rn
		1224292 FYN_RAT (6-82): 5.14e-28: 106: 30.00		BCAR1_RAT (6-431): 6.07e-12: 70.5: 20.23
+	Hs
		463316 LYN_HUMAN (3-83): 2.23e-28: 107: 28.92		MUC1_HUMAN (86-481): 2.99e-11: 68.6: 10.59
+	Mm
		683100 LYN_MOUSE (3-83): 8.44e-29: 108: 30.12		BCAR1_MOUSE (7-431): 9.64e-11: 66.6: 19.17
+	Mm
		813523 FYN_MOUSE (6-82): 5.14e-28: 106: 30.00		BCAR1_MOUSE (7-431): 9.64e-11: 66.6: 19.17