Interactor 1: E7ESA6 (E7ESA6)
Focal adhesion kinase 1 (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: PTK2

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments unassigned1853
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains COR~PK_Tyr_Ser-Thr, LRR_8~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1096
Hs

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Last updated: 11Aug2025