HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: RGPA1 (Q6GYQ0)
Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)
Gene: RALGAPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rap_GAP~Ras
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 2036
+	Hs
		988447 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		962161 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		1015524 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		955292 CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		978044 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		RGPA2_HUMAN (1-2030): 0: 2671: 49.46
+	Hs
		1015479 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		RGPA2_HUMAN (1-2030): 0: 2671: 49.46
+	Hs
		988604 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		SIPA1_HUMAN (1603-2018): 1.13e-117: 402: 16.91
+	Hs
		962371 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		SIPA1_HUMAN (1603-2018): 1.13e-117: 402: 16.91
+	Hs
		208649 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		SI1L1_HUMAN (1683-2015): 2.29e-106: 380: 19.22
+	Hs
		978371 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		SI1L2_HUMAN (1694-2016): 4.07e-106: 379: 18.88
+	Hs
		988497 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		RLGPB_HUMAN (1126-1884): 1.51e-105: 375: 16.67
+	Hs
		962230 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		RLGPB_HUMAN (1126-1884): 1.51e-105: 375: 16.67
+	Hs
		978129 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		RLGPB_HUMAN (1126-1884): 1.51e-105: 375: 16.67
+	Hs
		1015570 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		RLGPB_HUMAN (1126-1884): 1.51e-105: 375: 16.67
+	Hs
		955342 CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49		RLGPB_HUMAN (1126-1884): 1.51e-105: 375: 16.67
+	Dm
		828043 RAC1_DROME (1-196): 9.41e-78: 232: 53.06		X2JDH0_DROME (1637-2013): 4.14e-102: 367: 21.16
+	Dm
		828046 RAC1_DROME (1-196): 9.41e-78: 232: 53.06		X2JJU0_DROME (1637-2013): 3.71e-102: 367: 21.16
+	Hs
		244563 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		SI1L3_HUMAN (1691-2016): 1.33e-100: 362: 18.83
+	Hs
		244562 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		SI1L3_HUMAN (1691-2016): 1.33e-100: 362: 18.83
+	Hs
		890805 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		TSC2_HUMAN (1727-2033): 1.19e-96: 349: 23.90