HitPredict

Interactor 1: UB2G1 (P62253)
Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]
Gene: UBE2G1

Interactor 2: TRI63 (Q969Q1)
E3 ubiquitin-protein ligase TRIM63 (EC 2.3.2.27) (Iris RING finger protein) (Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (RING finger protein 28) (RING-type E3 ubiquitin transferase TRIM63) (Striated muscle RING zinc finger protein) (Tripartite motif-containing protein 63)
Gene: TRIM63

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	33106653
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 170 Hs			1 353
+	Hs
		970226 UB2G1_HUMAN (1-170): 3.68e-79: 234: 100.00		TRIM2_HUMAN (1-330): 3.05e-67: 226: 19.06
+	Hs
		1439327 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI39_HUMAN (14-352): 6.57e-71: 231: 16.53
+	Hs
		572291 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI27_HUMAN (8-353): 8.62e-70: 228: 17.76
+	Hs
		1419272 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI54_HUMAN (5-326): 3.52e-71: 227: 60.99
+	Hs
		1420598 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRIM2_HUMAN (1-330): 3.05e-67: 226: 19.06
+	Hs
		1384952 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI43_HUMAN (10-351): 5.04e-66: 217: 14.04
+	Hs
		1420192 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRIM8_HUMAN (15-330): 4.64e-64: 214: 20.87
+	Hs
		1420579 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRIM5_HUMAN (10-346): 3.06e-64: 213: 18.08
+	Hs
		142704 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI38_HUMAN (8-352): 3.65e-64: 212: 17.39
+	Hs
		142669 UB2D1_HUMAN (5-165): 3.33e-72: 215: 34.78		TRI38_HUMAN (8-352): 3.65e-64: 212: 17.39
+	Hs
		186599 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI18_HUMAN (14-345): 4.38e-62: 211: 22.28
+	Hs
		279076 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRIM3_HUMAN (4-346): 2.03e-61: 211: 17.61
+	Hs
		186519 UB2D1_HUMAN (5-165): 3.33e-72: 215: 34.78		TRI18_HUMAN (14-345): 4.38e-62: 211: 22.28
+	Hs
		1458960 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI10_HUMAN (8-353): 1e-62: 209: 15.41
+	Hs
		1460665 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRIM1_HUMAN (14-347): 1.15e-60: 208: 21.92
+	Hs
		1490991 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI17_HUMAN (8-344): 1.23e-62: 208: 19.88
+	Hs
		1233123 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		Q6GX22_HUMAN (14-347): 3.26e-60: 207: 21.92
+	Hs
		1420388 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI31_HUMAN (8-301): 1.25e-59: 199: 22.45
+	Hs
		1415212 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI62_HUMAN (16-276): 1.34e-16: 82.4: 24.35
+	Hs
		1294335 UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16		TRI50_HUMAN (14-250): 3.6e-14: 75.1: 25.00