HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSD12 (O00232)
26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)
Gene: PSMD12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~PSMD12-CSN4_N
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 301 Hs			1 456
+	Hs
		128140 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSD12_HUMAN (1-456): 2.11e-155: 449: 100.00
+	Hs
		128166 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSD12_HUMAN (1-456): 2.11e-155: 449: 100.00
+	Hs
		128196 PRS4_HUMAN (18-301): 3.79e-68: 220: 36.81		PSD12_HUMAN (1-456): 2.11e-155: 449: 100.00
+	Dm
		1464418 Q9V3V6_DROME (34-301): 1.28e-69: 223: 85.82		Q9V3Z4_DROME (11-455): 4.86e-121: 364: 46.67
+	Dm
		198067 PRS8_DROME (55-300): 1.63e-68: 220: 34.82		Q9V3Z4_DROME (11-455): 4.86e-121: 364: 46.67
+	Dm
		1267701 Q7KMQ0_DROME (14-300): 9.89e-68: 218: 31.36		Q9V3Z4_DROME (11-455): 4.86e-121: 364: 46.67
+	Dm
		874993 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		CSN4_DROME (45-450): 1.99e-91: 284: 20.00
+	Sc
		750803 PRS6A_YEAST (24-301): 2.46e-68: 220: 65.85		RPN5_YEAST (14-456): 3.38e-106: 324: 40.67
+	Dm
		874971 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSD11_DROME (28-443): 1.95e-86: 272: 15.21
+	Hs
		610285 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		CSN2_HUMAN (24-439): 1.11e-94: 294: 12.59
+	Hs
		97053 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSD11_HUMAN (27-443): 9.34e-90: 281: 15.44
+	Hs
		127872 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSD11_HUMAN (27-443): 9.34e-90: 281: 15.44
+	Hs
		958616 PRS4_HUMAN (18-301): 3.79e-68: 220: 36.81		CSN2_HUMAN (24-439): 1.11e-94: 294: 12.59
+	Hs
		127895 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSD11_HUMAN (27-443): 9.34e-90: 281: 15.44
+	At
		1442341 PS6AA_ARATH (37-301): 6.44e-69: 222: 76.69		PSD11_ARATH (27-442): 4.63e-90: 281: 16.40
+	Hs
		127923 PRS4_HUMAN (18-301): 3.79e-68: 220: 36.81		PSD11_HUMAN (27-443): 9.34e-90: 281: 15.44
+	Dm
		1267337 Q9V3V6_DROME (34-301): 1.28e-69: 223: 85.82		PSD11_DROME (28-443): 1.95e-86: 272: 15.21
+	Dm
		198047 PRS8_DROME (55-300): 1.63e-68: 220: 34.82		PSD11_DROME (28-443): 1.95e-86: 272: 15.21
+	Dm
		1267329 Q7KMQ0_DROME (14-300): 9.89e-68: 218: 31.36		PSD11_DROME (28-443): 1.95e-86: 272: 15.21
+	Sc
		750805 PRS6A_YEAST (24-301): 2.46e-68: 220: 65.85		RPN6_YEAST (26-452): 2.94e-77: 249: 14.48