HitPredict

Interactor 1: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Interactor 2: YTM1 (Q12024)
Ribosome biogenesis protein YTM1 (Microtubule-associated protein YTM1)
Gene: YTM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.726

Property	Details
Experiments	30568249, 31511893, 16429126, 16287855, 36929751, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0030687 - preribosome, large subunit precursor GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Sc			1 460
+	Hs
		1271615 DDX17_HUMAN (4-478): 1.71e-134: 407: 29.31		FBXW7_HUMAN (190-457): 6.72e-60: 209: 18.38
+	Hs
		134154 DDX3X_HUMAN (4-428): 1.25e-126: 385: 27.77		FBXW7_HUMAN (190-457): 6.72e-60: 209: 18.38
+	Sc
		630886 HAS1_YEAST (1-505): 1.8e-165: 479: 100.00		NLE1_YEAST (19-130): 2.91e-11: 67.5: 15.28
+	Sc
		624089 DBP2_YEAST (5-421): 8.67e-134: 400: 29.22		MET30_YEAST (137-452): 3.86e-34: 137: 19.26
+	Hs
		181721 DDX3Y_HUMAN (4-434): 8.05e-126: 383: 26.95		POC1A_HUMAN (8-234): 1.18e-31: 127: 13.48
+	Hs
		903549 DDX18_HUMAN (2-492): 3.3e-139: 418: 59.76		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Hs
		1271700 DDX17_HUMAN (4-478): 1.71e-134: 407: 29.31		FBW1A_HUMAN (101-246): 3.17e-19: 92.2: 19.65
+	Hs
		1271679 DDX17_HUMAN (4-478): 1.71e-134: 407: 29.31		NLE1_HUMAN (362-459): 3.92e-19: 91.7: 24.24
+	Hs
		1288337 DDX18_HUMAN (2-492): 3.3e-139: 418: 59.76		SNR40_HUMAN (362-459): 4.27e-15: 78.2: 18.18
+	Hs
		903410 DDX17_HUMAN (4-478): 1.71e-134: 407: 29.31		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Hs
		571638 DDX5_HUMAN (4-449): 2.8e-131: 395: 30.22		FBW1A_HUMAN (101-246): 3.17e-19: 92.2: 19.65
+	Hs
		1271621 DDX17_HUMAN (4-478): 1.71e-134: 407: 29.31		SNR40_HUMAN (362-459): 4.27e-15: 78.2: 18.18
+	Hs
		571382 DDX5_HUMAN (4-449): 2.8e-131: 395: 30.22		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Hs
		134256 DDX3X_HUMAN (4-428): 1.25e-126: 385: 27.77		FBW1A_HUMAN (101-246): 3.17e-19: 92.2: 19.65
+	Hs
		571547 DDX5_HUMAN (4-449): 2.8e-131: 395: 30.22		SNR40_HUMAN (362-459): 4.27e-15: 78.2: 18.18
+	Hs
		133956 DDX3X_HUMAN (4-428): 1.25e-126: 385: 27.77		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Hs
		134246 DDX3X_HUMAN (4-428): 1.25e-126: 385: 27.77		FBW1B_HUMAN (116-451): 1.16e-10: 65.5: 26.61
+	Hs
		1333547 DDX31_HUMAN (9-505): 3.72e-82: 274: 32.37		NLE1_HUMAN (362-459): 3.92e-19: 91.7: 24.24
+	Hs
		1288310 DDX31_HUMAN (9-505): 3.72e-82: 274: 32.37		SNR40_HUMAN (362-459): 4.27e-15: 78.2: 18.18
+	Sc
		630853 DRS1_YEAST (26-394): 3.8e-72: 245: 38.32		NLE1_YEAST (19-130): 2.91e-11: 67.5: 15.28