HitPredict

Interactor 1: MAD1 (Q05195)
Max dimerization protein 1 (Max dimerizer 1) (Protein MAD)
Gene: MXD1

Interactor 2: BRMS1 (Q9HCU9)
Breast cancer metastasis-suppressor 1
Gene: BRMS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 221 Hs			1 246
+	Hs
		983433 MAD1_HUMAN (1-221): 1.6e-77: 233: 100.00		BRM1L_HUMAN (11-246): 3.39e-81: 247: 54.24
+	Hs
		1314324 MAD3_HUMAN (8-191): 4.69e-53: 171: 45.88		BRMS1_HUMAN (1-246): 7.1e-95: 280: 100.00
+	Hs
		1129651 MAD3_HUMAN (8-191): 4.69e-53: 171: 45.88		BRM1L_HUMAN (11-246): 3.39e-81: 247: 54.24
+	Hs
		983445 MAD1_HUMAN (1-221): 1.6e-77: 233: 100.00		SDS3_HUMAN (34-238): 9.08e-54: 177: 21.26
+	Hs
		346984 MYC_HUMAN (39-139): 6.1e-32: 122: 22.77		BRM1L_HUMAN (11-246): 3.39e-81: 247: 54.24
+	Hs
		1314322 MAD3_HUMAN (8-191): 4.69e-53: 171: 45.88		SDS3_HUMAN (34-238): 9.08e-54: 177: 21.26
+	Hs
		898202 MAX_HUMAN (53-155): 4.73e-12: 63.6: 24.27		BRMS1_HUMAN (1-246): 7.1e-95: 280: 100.00
+	Hs
		898137 MAX_HUMAN (53-155): 4.73e-12: 63.6: 24.27		BRM1L_HUMAN (11-246): 3.39e-81: 247: 54.24
+	Hs
		898195 MAX_HUMAN (53-155): 4.73e-12: 63.6: 24.27		SDS3_HUMAN (34-238): 9.08e-54: 177: 21.26