HitPredict

Interactor 1: GBB1 (P62874)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: Gnb1

Interactor 2: GBG2 (P63213)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (G gamma-I)
Gene: Gng2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8550614
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005834 - heterotrimeric G-protein complex GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Mm			1 71
+	Hs
		948052 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBG2_HUMAN (1-71): 3.59e-29: 100: 100.00
+	Hs
		948051 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GBG2_HUMAN (1-71): 3.59e-29: 100: 100.00
+	Bt
		983440 GBB1_BOVIN (1-340): 1.7e-106: 316: 100.00		GBG2_BOVIN (1-71): 3.59e-29: 100: 100.00
+	Hs
		893551 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBG4_HUMAN (1-71): 6.57e-28: 97: 77.47
+	Hs
		984064 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBG3_HUMAN (4-71): 3.15e-27: 95.1: 79.41
+	Hs
		893550 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GBG4_HUMAN (1-71): 6.57e-28: 97: 77.47
+	Hs
		984327 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBG8_HUMAN (3-71): 8.54e-26: 91.7: 71.01
+	Hs
		243467 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBG7_HUMAN (4-71): 4.44e-25: 89.7: 70.59
+	Hs
		243466 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GBG7_HUMAN (4-71): 4.44e-25: 89.7: 70.59
+	Hs
		984316 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBG12_HUMAN (3-71): 4.48e-24: 87: 62.32
+	Hs
		893565 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBG10_HUMAN (4-71): 4.36e-22: 82: 52.94
+	Hs
		893564 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GBG10_HUMAN (4-71): 4.36e-22: 82: 52.94
+	Hs
		984065 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBG5_HUMAN (4-71): 4.13e-21: 79.7: 48.53
+	Hs
		984063 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBG1_HUMAN (11-70): 2.95e-20: 77.8: 38.33
+	Hs
		992415 Q6FHM2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBG1_HUMAN (11-70): 2.95e-20: 77.8: 38.33
+	Bt
		388107 GBB1_BOVIN (1-340): 1.7e-106: 316: 100.00		GBG1_BOVIN (11-70): 1.49e-20: 78.2: 38.33
+	Hs
		158713 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GBGT2_HUMAN (12-70): 5.69e-17: 69.3: 44.07
+	Hs
		158712 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GBGT2_HUMAN (12-70): 5.69e-17: 69.3: 44.07
+	Ce
		604386 GBB1_CAEEL (1-340): 2.21e-107: 318: 85.88		GBG_CAEEL (12-71): 2.78e-14: 62: 40.00
+	Ce
		111110 GBB1_CAEEL (1-340): 2.21e-107: 318: 85.88		G5ECT6_CAEEL (10-71): 1.3e-13: 60.5: 32.26