Interactor 1: F1MAL5 (F1MAL5)
Insulin receptor substrate 2
Gene: Irs2
Interactor 2: GRB2 (P62994)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12960006 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~SH3_1 |
| Common GO terms | GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008286 - insulin receptor signaling pathway and 5 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
