HitPredict

Interactor 1: TNR9 (Q07011)
Tumor necrosis factor receptor superfamily member 9 (4-1BB ligand receptor) (CDw137) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD antigen CD137)
Gene: TNFRSF9

Interactor 2: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	9607925, 9464265, 15941918
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006915 - apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 255 Hs			1 416
+	Mm
		591444 TNR9_MOUSE (1-247): 9.28e-58: 186: 56.05		TRAF1_MOUSE (1-416): 4.49e-160: 458: 84.38
+	Hs
		1023845 TNR18_HUMAN (60-251): 1.32e-43: 149: 26.50		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Hs
		1023848 TNR11_HUMAN (27-202): 2.07e-39: 146: 24.35		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Hs
		989742 TNR9_HUMAN (1-255): 2.7e-75: 230: 100.00		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Mm
		591445 TNR9_MOUSE (1-247): 9.28e-58: 186: 56.05		TRAF2_MOUSE (3-415): 3.91e-127: 378: 37.77
+	Mm
		192583 TNR11_MOUSE (27-202): 2.04e-42: 154: 24.35		TRAF2_MOUSE (3-415): 3.91e-127: 378: 37.77
+	Hs
		1021005 TNR18_HUMAN (60-251): 1.32e-43: 149: 26.50		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		1021008 TNR11_HUMAN (27-202): 2.07e-39: 146: 24.35		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Mm
		192585 TNR11_MOUSE (27-202): 2.04e-42: 154: 24.35		TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51
+	Hs
		1377881 TNR11_HUMAN (27-202): 2.07e-39: 146: 24.35		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		129553 TNR9_HUMAN (1-255): 2.7e-75: 230: 100.00		TRAF5_HUMAN (14-261): 1.36e-16: 83.8: 13.91
+	Hs
		989744 TNR9_HUMAN (1-255): 2.7e-75: 230: 100.00		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Hs
		989752 TNR9_HUMAN (1-255): 2.7e-75: 230: 100.00		TRAF4_HUMAN (27-136): 3.55e-09: 60.3: 17.86
+	Mm
		591448 TNR9_MOUSE (1-247): 9.28e-58: 186: 56.05		TRAF3_MOUSE (1-262): 2.34e-12: 70.7: 16.37
+	Hs
		129607 TNR11_HUMAN (27-202): 2.07e-39: 146: 24.35		TRAF5_HUMAN (14-261): 1.36e-16: 83.8: 13.91
+	Mm
		192584 TNR11_MOUSE (27-202): 2.04e-42: 154: 24.35		TRAF5_MOUSE (14-296): 7.86e-13: 71.9: 13.45
+	Mm
		192587 TNR11_MOUSE (27-202): 2.04e-42: 154: 24.35		TRAF3_MOUSE (1-262): 2.34e-12: 70.7: 16.37
+	Hs
		129536 TNR3_HUMAN (24-172): 1.12e-35: 133: 28.24		TRAF5_HUMAN (14-261): 1.36e-16: 83.8: 13.91
+	Hs
		1024793 TNR18_HUMAN (60-251): 1.32e-43: 149: 26.50		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Hs
		1024798 TNR11_HUMAN (27-202): 2.07e-39: 146: 24.35		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77