HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: DDX31 (Q9H8H2)
ATP-dependent DNA helicase DDX31 (EC 3.6.4.12) (DEAD box protein 31) (Helicain) (Probable ATP-dependent RNA helicase DDX31) (EC 3.6.4.13)
Gene: DDX31

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005730 - nucleolus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 851
+	Hs
		418714 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DDX18_HUMAN (154-753): 2.72e-163: 492: 31.53
+	Hs
		418478 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DDX55_HUMAN (225-762): 5.96e-161: 483: 29.80
+	Hs
		418645 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DDX47_HUMAN (206-690): 6.82e-149: 447: 26.96
+	Mm
		1143199 NPM_MOUSE (1-294): 7.04e-141: 400: 93.54		Q8BTS0_MOUSE (110-817): 7.93e-140: 429: 20.96
+	Hs
		133844 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DDX3X_HUMAN (73-667): 6.93e-135: 418: 21.28
+	Hs
		271418 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		DDX31_HUMAN (1-851): 0: 616: 100.00
+	Hs
		271430 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		DDX18_HUMAN (154-753): 2.72e-163: 492: 31.53
+	Hs
		418232 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DDX10_HUMAN (254-754): 2.78e-64: 233: 34.20
+	Hs
		271316 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		DDX10_HUMAN (254-754): 2.78e-64: 233: 34.20