HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: ARG28 (P97433)
Rho guanine nucleotide exchange factor 28 (190 kDa guanine nucleotide exchange factor) (p190-RhoGEF) (p190RhoGEF) (Rho guanine nucleotide exchange factor) (Rho-interacting protein 2)
Gene: Arhgef28

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	11533041
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Mm			1 1700
+	Mm
		972203 1433E_MOUSE (2-241): 9.95e-144: 403: 68.18		ARG28_MOUSE (1-1700): 0: 1195: 100.00
+	Hs
		990486 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ARG28_HUMAN (1-1700): 0: 1171: 80.04
+	Hs
		971770 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		ARG28_HUMAN (1-1700): 0: 1171: 80.04
+	Hs
		990154 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		AKP13_HUMAN (1-858): 9.82e-128: 447: 16.18
+	Hs
		971453 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		AKP13_HUMAN (1-858): 9.82e-128: 447: 16.18
+	Mm
		989969 1433Z_MOUSE (1-245): 3.49e-145: 407: 100.00		ARHG2_MOUSE (614-1604): 3.76e-119: 403: 32.72
+	Mm
		989989 1433Z_MOUSE (1-245): 3.49e-145: 407: 100.00		ARHGI_MOUSE (370-1616): 3.32e-116: 403: 32.69
+	Hs
		990578 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ARHG2_HUMAN (614-1604): 2.53e-117: 398: 33.63
+	Hs
		990387 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ARHGI_HUMAN (384-1616): 2.17e-111: 389: 33.44
+	Hs
		990390 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		FGD6_HUMAN (565-1353): 1.31e-90: 327: 14.46
+	Hs
		971683 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		FGD6_HUMAN (565-1353): 1.31e-90: 327: 14.46
+	Hs
		990164 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		TIAM1_HUMAN (632-1444): 1.84e-84: 309: 13.69
+	Hs
		971463 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		TIAM1_HUMAN (632-1444): 1.84e-84: 309: 13.69
+	Mm
		989945 1433Z_MOUSE (1-245): 3.49e-145: 407: 100.00		RGRF2_MOUSE (680-1500): 1.43e-78: 287: 14.58
+	Hs
		990617 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		SPT13_HUMAN (609-1264): 3.57e-83: 289: 12.90
+	Hs
		990776 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ARHG4_HUMAN (811-1262): 1.41e-81: 286: 15.90
+	Hs
		990855 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		MYH2_HUMAN (973-1695): 7.48e-76: 282: 9.57
+	Hs
		535929 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		MYH3_HUMAN (970-1695): 2.11e-75: 280: 10.47
+	Hs
		318087 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PKHG5_HUMAN (825-1332): 1.75e-38: 159: 17.66
+	Hs
		318086 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		PKHG5_HUMAN (825-1332): 1.75e-38: 159: 17.66