HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: TCOF (Q13428)
Treacle protein (Treacher Collins syndrome protein)
Gene: TCOF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30890647
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 1488
+	Hs
		995592 ACTC_HUMAN (1-377): 0: 599: 100.00		MDC1_HUMAN (59-1388): 1.46e-46: 186: 10.51
+	Dm
		534353 ACT5_DROME (1-377): 0: 597: 93.10		CPN_DROME (499-1322): 9.51e-20: 98.3: 10.56
+	Hs
		995914 ACTC_HUMAN (1-377): 0: 599: 100.00		WNK2_HUMAN (41-1454): 3.95e-17: 90: 9.45
+	Hs
		590266 ACTA_HUMAN (1-377): 0: 597: 98.41		MUC1_HUMAN (804-1442): 3.52e-17: 90.2: 11.32
+	Dm
		56405 ACT6_DROME (1-377): 0: 594: 92.84		A1ZA72_DROME (61-1471): 1.01e-17: 92.5: 15.45
+	Hs
		952822 ACTB_HUMAN (4-377): 0: 598: 94.12		NCOA6_HUMAN (370-1466): 6.08e-15: 83.1: 7.27
+	Hs
		215916 ACTC_HUMAN (1-377): 0: 599: 100.00		SYNJ1_HUMAN (175-679): 9.37e-11: 69: 17.82
+	Hs
		995656 ACTC_HUMAN (1-377): 0: 599: 100.00		SRCAP_HUMAN (103-719): 5.25e-10: 66.7: 17.09
+	Hs
		952913 ACTB_HUMAN (4-377): 0: 598: 94.12		SRCAP_HUMAN (103-719): 5.25e-10: 66.7: 17.09
+	Hs
		993223 ACTG_HUMAN (4-377): 0: 598: 94.39		SRCAP_HUMAN (103-719): 5.25e-10: 66.7: 17.09
+	Hs
		952752 ACTB_HUMAN (4-377): 0: 598: 94.12		ANK2_HUMAN (195-1161): 9.85e-10: 65.9: 15.17
+	Hs
		952948 ACTB_HUMAN (4-377): 0: 598: 94.12		MILK2_HUMAN (420-909): 2.22e-09: 64.4: 19.48
+	Hs
		993416 ACTH_HUMAN (4-377): 0: 591: 98.93		ANK2_HUMAN (195-1161): 9.85e-10: 65.9: 15.17