Protein: SEM4D
Semaphorin-4D (A8) (BB18) (GR3) (CD antigen CD100)

Gene: SEM4D, SEMA4D
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q92854

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001755 - neural crest cell migration
GO:0001934 - positive regulation of protein phosphorylation
GO:0002116 - semaphorin receptor complex
GO:0004888 - transmembrane signaling receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

351718

SG1D1
Secretoglobin family 1D member 1

2

2

High-throughput

0.811

High

619881

VCAM1
Vascular cell adhesion protein 1

2

4

High-throughput

0.811

High

208134

PLXB1
Plexin-B1

2

20

Small-scale

0.802

High

1369565

SEM4D
Semaphorin-4D

2

14

Small-scale

0.802

High

471750

PTPRC
Receptor-type tyrosine-protein phosphatase C

2

2

Small-scale

0.754

High

249180

DSCAM
Cell adhesion molecule DSCAM

1

3

High-throughput

0.698

High

1101395

SG2A2
Mammaglobin-A

1

2

High-throughput

0.691

High

1369570

BTNL2
Butyrophilin-like protein 2

1

4

High-throughput

0.691

High

641470

CD72
B-cell differentiation antigen CD72

2

8

Small-scale

0.595

High

855712

CRK
Adapter molecule crk

2

8

High-throughput

0.594

High

375804

RASK
GTPase KRas

2

11

High-throughput

0.584

High

480872

LEG1
Galectin-1

1

1

High-throughput

0.536

High

688604

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

11

High-throughput

0.536

High

1369566

T106A
Transmembrane protein 106A

1

4

High-throughput

0.536

High

1369568

CST9L
Cystatin-9-like

1

4

High-throughput

0.536

High

976844

LCN6
Epididymal-specific lipocalin-6

1

3

High-throughput

0.489

High

1177856

CL12B
C-type lectin domain family 12 member B

1

9

High-throughput

0.489

High

1359219

CA054
Uncharacterized protein C1orf54

1

5

High-throughput

0.489

High

1369569

SDF2L
Stromal cell-derived factor 2-like protein 1

1

5

High-throughput

0.489

High

1369571

FBX2
F-box only protein 2

1

9

High-throughput

0.489

High

374111

RASN
GTPase NRas

1

11

High-throughput

0.479

High

1325504

FBXW8
F-box/WD repeat-containing protein 8

1

2

High-throughput

0.479

High

885176

TTPA
Alpha-tocopherol transfer protein

1

1

High-throughput

0.437

High

1310767

CUL9
Cullin-9

1

1

High-throughput

0.437

High

1369567

DJC25
DnaJ homolog subfamily C member 25

1

8

High-throughput

0.437

High

869639

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

0

High-throughput

0.426

High

119

A0A024R161
Guanine nucleotide-binding protein subunit gamma

1

8

High-throughput

0.407

High

1362518

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

0

High-throughput

0.328

High

1333415

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025