Protein: LCN6
Epididymal-specific lipocalin-6 (Lipocalin-5)

Gene: LCN6
Organism: Homo sapiens
Interactions: 124
UniProt ID: P62502

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0007340 - acrosome reaction
GO:0019725 - cellular homeostasis
GO:0036094 - small molecule binding
GO:0048469 - cell maturation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

282832

CRLF1
Cytokine receptor-like factor 1

1

1

High-throughput

0.691

High

586371

ARSB
Arylsulfatase B

2

4

High-throughput

0.601

High

976820

GLB1L
Beta-galactosidase-1-like protein

2

1

High-throughput

0.601

High

976842

PXDN
Peroxidasin homolog

2

0

High-throughput

0.576

High

976847

I17RA
Interleukin-17 receptor A

2

0

High-throughput

0.576

High

249454

ACSL4
Long-chain-fatty-acid--CoA ligase 4

2

1

High-throughput

0.549

High

914837

NDST1
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

2

1

High-throughput

0.549

High

942484

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

2

1

High-throughput

0.549

High

976807

MA2A1
Alpha-mannosidase 2

2

2

High-throughput

0.549

High

976810

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

2

1

High-throughput

0.549

High

976819

PLGT2
Protein O-glucosyltransferase 2

2

2

High-throughput

0.549

High

976826

CHSS3
Chondroitin sulfate synthase 3

2

7

High-throughput

0.549

High

976858

SIL1
Nucleotide exchange factor SIL1

2

1

High-throughput

0.549

High

976868

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

2

4

High-throughput

0.549

High

976869

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

2

1

High-throughput

0.549

High

976872

CHPF2
Chondroitin sulfate glucuronyltransferase

2

5

High-throughput

0.549

High

976875

CEIP2
Cell surface hyaluronidase CEMIP2

2

1

High-throughput

0.549

High

215711

COCH
Cochlin

1

3

High-throughput

0.536

High

450173

GDN
Glia-derived nexin

1

3

High-throughput

0.536

High

562711

BMP1
Bone morphogenetic protein 1

1

2

High-throughput

0.536

High

611716

BMP7
Bone morphogenetic protein 7

1

2

High-throughput

0.536

High

976801

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

1

3

High-throughput

0.536

High

976821

ARSK
Arylsulfatase K

1

3

High-throughput

0.536

High

976831

R4RL2
Reticulon-4 receptor-like 2

1

1

High-throughput

0.536

High

976832

CHSS1
Chondroitin sulfate synthase 1

1

7

High-throughput

0.536

High

976834

SULF2
Extracellular sulfatase Sulf-2

1

3

High-throughput

0.536

High

976852

NAR5
Ecto-ADP-ribosyltransferase 5

1

1

High-throughput

0.536

High

441417

CHLE
Cholinesterase

1

0

High-throughput

0.513

High

833454

WNT5A
Protein Wnt-5a

1

0

High-throughput

0.513

High

933996

PLTP
Phospholipid transfer protein

1

0

High-throughput

0.513

High

976846

NXPE3
NXPE family member 3

1

0

High-throughput

0.513

High

62927

POTEF
POTE ankyrin domain family member F

1

1

High-throughput

0.489

High

164732

HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1

1

1

High-throughput

0.489

High

335383

GDF11
Growth/differentiation factor 11

1

2

High-throughput

0.489

High

534891

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.489

High

557201

SRC
Proto-oncogene tyrosine-protein kinase Src

1

2

High-throughput

0.489

High

565304

ITA4
Integrin alpha-4

1

6

High-throughput

0.489

High

896363

ERF
ETS domain-containing transcription factor ERF

1

2

High-throughput

0.489

High

976817

TXD11
Thioredoxin domain-containing protein 11

1

3

High-throughput

0.489

High

976835

MICU2
Calcium uptake protein 2, mitochondrial

1

3

High-throughput

0.489

High

976836

PGLT1
Protein O-glucosyltransferase 1

1

2

High-throughput

0.489

High

976844

SEM4D
Semaphorin-4D

1

3

High-throughput

0.489

High

976848

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

1

1

High-throughput

0.489

High

976850

TXD15
Thioredoxin domain-containing protein 15

1

3

High-throughput

0.489

High

976859

SEM6B
Semaphorin-6B

1

3

High-throughput

0.489

High

976866

CHST7
Carbohydrate sulfotransferase 7

1

1

High-throughput

0.489

High

976867

SEM4G
Semaphorin-4G

1

3

High-throughput

0.489

High

976874

B4GT6
Beta-1,4-galactosyltransferase 6

1

1

High-throughput

0.489

High

976878

TRHDE
Thyrotropin-releasing hormone-degrading ectoenzyme

1

1

High-throughput

0.489

High

976880

MA2B2
Epididymis-specific alpha-mannosidase

1

2

High-throughput

0.489

High

144050

MA2B1
Lysosomal alpha-mannosidase

1

2

High-throughput

0.445

High

251146

B4GT4
Beta-1,4-galactosyltransferase 4

1

1

High-throughput

0.445

High

350700

NOE2
Noelin-2

1

2

High-throughput

0.445

High

452088

PROS
Vitamin K-dependent protein S

1

5

High-throughput

0.445

High

501809

CO4A
Complement C4-A

1

3

High-throughput

0.445

High

551848

CO6A2

1

2

High-throughput

0.445

High

593655

BGAL
Beta-galactosidase

1

1

High-throughput

0.445

High

756541

GALNS
N-acetylgalactosamine-6-sulfatase

1

3

High-throughput

0.445

High

976802

SEM3B
Semaphorin-3B

1

3

High-throughput

0.445

High

976803

DNJC3
DnaJ homolog subfamily C member 3

1

2

High-throughput

0.445

High

976823

CD109
CD109 antigen

1

3

High-throughput

0.445

High

976838

LFNG
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

1

6

High-throughput

0.445

High

976863

IL1AP
Interleukin-1 receptor accessory protein

1

1

High-throughput

0.445

High

277006

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

1

0

High-throughput

0.426

High

366482

UROK
Urokinase-type plasminogen activator

1

0

High-throughput

0.426

High

774755

TIMP3
Metalloproteinase inhibitor 3

1

0

High-throughput

0.426

High

976841

CANT1
Soluble calcium-activated nucleotidase 1

1

0

High-throughput

0.426

High

976843

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.426

High

71163

HIG1C
HIG1 domain family member 1C

1

1

High-throughput

0.407

High

363090

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.407

High

465473

IGF1R
Insulin-like growth factor 1 receptor

1

2

High-throughput

0.407

High

976799

CNTP1
Contactin-associated protein 1

1

1

High-throughput

0.407

High

976800

RHG01
Rho GTPase-activating protein 1

1

2

High-throughput

0.407

High

976805

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

6

High-throughput

0.407

High

976806

EXT1
Exostosin-1

1

1

High-throughput

0.407

High

976808

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

1

High-throughput

0.407

High

976816

TECT3
Tectonic-3

1

1

High-throughput

0.407

High

976818

MOXD1
DBH-like monooxygenase protein 1

1

1

High-throughput

0.407

High

976822

B3GLT
Beta-1,3-glucosyltransferase

1

6

High-throughput

0.407

High

976825

QSOX2
Sulfhydryl oxidase 2

1

2

High-throughput

0.407

High

976827

CHST3
Carbohydrate sulfotransferase 3

1

1

High-throughput

0.407

High

976828

PLGT3
Protein O-glucosyltransferase 3

1

2

High-throughput

0.407

High

976829

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

6

High-throughput

0.407

High

976830

GALT7
N-acetylgalactosaminyltransferase 7

1

1

High-throughput

0.407

High

976845

TP4A1
Protein tyrosine phosphatase type IVA 1

1

1

High-throughput

0.407

High

976849

GLT14
Polypeptide N-acetylgalactosaminyltransferase 14

1

1

High-throughput

0.407

High

976855

DCBD2
Discoidin, CUB and LCCL domain-containing protein 2

1

3

High-throughput

0.407

High

976856

S2533
Solute carrier family 25 member 33

1

6

High-throughput

0.407

High

976865

OLFL3
Olfactomedin-like protein 3

1

2

High-throughput

0.407

High

976870

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

1

High-throughput

0.407

High

976876

PLXA1
Plexin-A1

1

1

High-throughput

0.407

High

976877

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

1

1

High-throughput

0.407

High

976879

HIG1A
HIG1 domain family member 1A, mitochondrial

1

1

High-throughput

0.407

High

976813

GT253
Inactive glycosyltransferase 25 family member 3

2

0

High-throughput

0.313

High

976833

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

2

0

High-throughput

0.313

High

976873

CATF
Cathepsin F

2

0

High-throughput

0.313

High

253754

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.279

Low

283677

GPC4
Glypican-4

1

0

High-throughput

0.279

Low

648275

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

1

0

High-throughput

0.279

Low

771658

IDUA
Alpha-L-iduronidase

1

0

High-throughput

0.279

Low

976804

OS9
Protein OS-9

1

0

High-throughput

0.279

Low

976824

CO039
Uncharacterized protein C15orf39

1

0

High-throughput

0.279

Low

976837

CNNM3
Metal transporter CNNM3

1

0

High-throughput

0.279

Low

976851

LMLN
Leishmanolysin-like peptidase

1

0

High-throughput

0.279

Low

976853

H6ST2
Heparan-sulfate 6-O-sulfotransferase 2

1

0

High-throughput

0.279

Low

976854

F210A
Protein FAM210A

1

0

High-throughput

0.279

Low

976857

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.279

Low

976864

CHSTC
Carbohydrate sulfotransferase 12

1

0

High-throughput

0.279

Low

976871

TEN3
Teneurin-3

1

0

High-throughput

0.279

Low

161017

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

0

High-throughput

0.232

Low

212942

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.232

Low

843043

PCP
Lysosomal Pro-X carboxypeptidase

1

0

High-throughput

0.232

Low

932357

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.232

Low

976809

VATF
V-type proton ATPase subunit F

1

0

High-throughput

0.232

Low

976811

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.232

Low

976812

TM177
Transmembrane protein 177

1

0

High-throughput

0.232

Low

976814

LYPL1
Lysophospholipase-like protein 1

1

0

High-throughput

0.232

Low

976815

MYORG
Myogenesis-regulating glycosidase

1

0

High-throughput

0.232

Low

976839

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.232

Low

976840

SCRB1
Scavenger receptor class B member 1

1

0

High-throughput

0.232

Low

976860

OFUT1
GDP-fucose protein O-fucosyltransferase 1

1

0

High-throughput

0.232

Low

976861

TRABD
TraB domain-containing protein

1

0

High-throughput

0.232

Low

976862

RISC
Retinoid-inducible serine carboxypeptidase

1

0

High-throughput

0.232

Low

976881

SQOR
Sulfide:quinone oxidoreductase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025