Protein: WFDC2
WAP four-disulfide core domain protein 2 (Epididymal secretory protein E4) (Major epididymis-specific protein E4) (Putative protease inhibitor WAP5)

Gene: WFDC2
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q14508

Gene Ontology (top 5):
GO:0004866 - endopeptidase inhibitor activity
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

522661

PTPRF
Receptor-type tyrosine-protein phosphatase F

2

0

High-throughput

0.602

High

1127336

CRAC1
Cartilage acidic protein 1

2

0

High-throughput

0.602

High

456731

ANXA2
Annexin A2

2

0

Small-scale

0.591

High

690250

STOM
Stomatin

2

0

High-throughput

0.580

High

1127330

F209A
Protein FAM209A

2

0

High-throughput

0.580

High

636731

PTN
Pleiotrophin

1

0

High-throughput

0.518

High

705336

GRN
Progranulin

1

0

High-throughput

0.513

High

469678

MMP2
72 kDa type IV collagenase

1

0

Small-scale

0.479

High

447756

TPM3
Tropomyosin alpha-3 chain

1

0

Small-scale

0.426

High

457441

TBB5
Tubulin beta chain

1

0

Small-scale

0.426

High

555684

ACTN1
Alpha-actinin-1

1

0

Small-scale

0.426

High

772799

MYH9
Myosin-9

1

0

Small-scale

0.426

High

952819

ACTB
Actin, cytoplasmic 1

1

0

Small-scale

0.426

High

1127338

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

4

0

High-throughput

0.364

High

62054

WDR91
WD repeat-containing protein 91

2

0

High-throughput

0.328

High

1127326

PDIA5
Protein disulfide-isomerase A5

2

0

High-throughput

0.328

High

1127328

WDR81
WD repeat-containing protein 81

2

0

High-throughput

0.328

High

50099

S22AN
Solute carrier family 22 member 23

2

0

High-throughput

0.316

High

275021

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

2

0

High-throughput

0.316

High

359984

NB5R3
NADH-cytochrome b5 reductase 3

2

0

High-throughput

0.316

High

549772

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.316

High

1127327

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

1127331

GORAB
RAB6-interacting golgin

2

0

High-throughput

0.316

High

1127332

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

1127333

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

0

High-throughput

0.316

High

1127334

PANX1
Pannexin-1

2

0

High-throughput

0.316

High

1127337

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.316

High

867784

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.279

Low

1127329

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.279

Low

1127335

BTBD1
BTB/POZ domain-containing protein 1

1

0

High-throughput

0.279

Low

385738

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

573298

ACYP2
Acylphosphatase-2

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025