Protein: IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform) (eIF1A X isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C)

Gene: IF1AX, EIF1AX
Organism: Homo sapiens
Interactions: 112
UniProt ID: P47813

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

158620

IF1AY
Eukaryotic translation initiation factor 1A, Y-chromosomal

4

1

High-throughput

0.895

High

318123

IPO13
Importin-13

3

1

Small-scale

0.678

High

867770

IF5
Eukaryotic translation initiation factor 5

1

1

Small-scale

0.653

High

867767

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

1

High-throughput

0.618

High

290386

RFPL3
Ret finger protein-like 3

2

0

High-throughput

0.580

High

395667

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

858595

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

2

High-throughput

0.571

High

867787

KPCD1
Serine/threonine-protein kinase D1

2

1

High-throughput

0.571

High

867791

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.547

High

867837

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.537

High

867797

STAC2
SH3 and cysteine-rich domain-containing protein 2

1

2

High-throughput

0.536

High

867813

RNF31
E3 ubiquitin-protein ligase RNF31

1

3

High-throughput

0.536

High

415421

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

867783

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

1

Small-scale

0.516

High

298323

DNJC8
DnaJ homolog subfamily C member 8

1

0

High-throughput

0.513

High

361161

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

446755

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

529312

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

531016

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

0

High-throughput

0.513

High

693596

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

867781

STRN3
Striatin-3

1

0

High-throughput

0.513

High

867795

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

1

0

High-throughput

0.513

High

867802

CD20B
Cell division cycle protein 20 homolog B

1

0

High-throughput

0.513

High

867814

DTBP1
Dysbindin

1

0

High-throughput

0.513

High

867815

NRBF2
Nuclear receptor-binding factor 2

1

0

High-throughput

0.513

High

867823

RAMAC
RNA guanine-N7 methyltransferase activating subunit

1

0

High-throughput

0.513

High

867825

HINT3
Adenosine 5'-monophosphoramidase HINT3

1

0

High-throughput

0.513

High

867830

CTNA3
Catenin alpha-3

1

0

High-throughput

0.513

High

867836

SPIN1
Spindlin-1

1

0

High-throughput

0.513

High

867776

RAN
GTP-binding nuclear protein Ran

1

0

Small-scale

0.512

High

867820

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

Small-scale

0.494

High

543411

PSG1
Pregnancy-specific beta-1-glycoprotein 1

1

1

High-throughput

0.489

High

665957

IBP5
Insulin-like growth factor-binding protein 5

1

1

High-throughput

0.489

High

867824

MND1
Meiotic nuclear division protein 1 homolog

1

1

High-throughput

0.489

High

421693

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

170007

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

254555

EIF1B
Eukaryotic translation initiation factor 1b

1

1

High-throughput

0.479

High

256798

H2B1K
Histone H2B type 1-K

1

7

High-throughput

0.479

High

324635

HEXI1
Protein HEXIM1

1

2

High-throughput

0.479

High

449689

H2B1J
Histone H2B type 1-J

1

7

High-throughput

0.479

High

754757

H2B1B
Histone H2B type 1-B

1

7

High-throughput

0.479

High

867769

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.479

High

867773

H2B1D
Histone H2B type 1-D

1

7

High-throughput

0.479

High

867775

H2B1C
Histone H2B type 1-C/E/F/G/I

1

7

High-throughput

0.479

High

867777

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

2

High-throughput

0.479

High

867778

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

1

High-throughput

0.479

High

867785

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

867789

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

867798

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

867799

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.479

High

867810

H2B1H
Histone H2B type 1-H

1

7

High-throughput

0.479

High

867821

H2B1L
Histone H2B type 1-L

1

7

High-throughput

0.479

High

867829

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

867834

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

241033

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

247737

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

298257

BODG
Gamma-butyrobetaine dioxygenase

1

0

High-throughput

0.458

High

376755

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

459836

PMGE
Bisphosphoglycerate mutase

1

0

High-throughput

0.458

High

479201

THIK
3-ketoacyl-CoA thiolase, peroxisomal

1

0

High-throughput

0.458

High

549091

CDK4
Cyclin-dependent kinase 4

1

0

High-throughput

0.458

High

606402

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

675407

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

822519

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

845958

DCC
Netrin receptor DCC

1

0

Small-scale

0.458

High

867768

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

867771

NP1L1
Nucleosome assembly protein 1-like 1

1

0

High-throughput

0.458

High

867772

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

867774

H4
Histone H4

1

0

High-throughput

0.458

High

867780

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

0

Small-scale

0.458

High

867782

HAP28
28 kDa heat- and acid-stable phosphoprotein

1

0

High-throughput

0.458

High

867788

CHD9
Chromodomain-helicase-DNA-binding protein 9

1

0

High-throughput

0.458

High

867790

SGO2
Shugoshin 2

1

0

High-throughput

0.458

High

867794

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

867800

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

Small-scale

0.458

High

867801

DDX42
ATP-dependent RNA helicase DDX42

1

0

High-throughput

0.458

High

867804

KCD17
BTB/POZ domain-containing protein KCTD17

1

0

High-throughput

0.458

High

867805

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.458

High

867806

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

867807

R3GEF
Guanine nucleotide exchange factor for Rab-3A

1

0

High-throughput

0.458

High

867809

TFG
Protein TFG

1

0

High-throughput

0.458

High

867818

LRAT2
Protein LRATD2

1

0

High-throughput

0.458

High

867819

HUTI
Probable imidazolonepropionase

1

0

High-throughput

0.458

High

867822

EFC4B
EF-hand calcium-binding domain-containing protein 4B

1

0

High-throughput

0.458

High

867826

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

867828

RRBP1
Ribosome-binding protein 1

1

0

High-throughput

0.458

High

867831

LCMT1
Leucine carboxyl methyltransferase 1

1

0

High-throughput

0.458

High

641524

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

1

High-throughput

0.437

High

867811

H2B1A
Histone H2B type 1-A

1

7

High-throughput

0.437

High

867812

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

1

High-throughput

0.437

High

354592

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.426

High

867779

TAGL
Transgelin

1

0

High-throughput

0.426

High

867793

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

0

High-throughput

0.328

High

664919

CRHBP
Corticotropin-releasing factor-binding protein

2

0

High-throughput

0.318

High

231212

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.279

Low

603627

JUNB
Transcription factor JunB

1

0

High-throughput

0.279

Low

867784

WFDC2
WAP four-disulfide core domain protein 2

1

0

High-throughput

0.279

Low

867786

PDK3
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

867792

MTCL3
Microtubule cross-linking factor 3

1

0

High-throughput

0.279

Low

867796

FAH2B
Oxaloacetate tautomerase FAHD2B, mitochondrial

1

0

High-throughput

0.279

Low

867803

P66A
Transcriptional repressor p66-alpha

1

0

High-throughput

0.279

Low

867808

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

867816

BORC8
BLOC-1-related complex subunit 8

1

0

High-throughput

0.279

Low

867835

NGN3
Neurogenin-3

1

0

High-throughput

0.279

Low

371433

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

455957

ASGR2
Asialoglycoprotein receptor 2

1

0

High-throughput

0.249

Low

502267

H2A1
Histone H2A type 1

1

0

High-throughput

0.249

Low

867817

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

0

High-throughput

0.249

Low

867827

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

867832

BAZ1B
Tyrosine-protein kinase BAZ1B

1

0

High-throughput

0.249

Low

867833

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025