Protein: RS21
Small ribosomal subunit protein eS21 (40S ribosomal protein S21) (Overgrown hematopoietic organs at 23B)

Gene: RS21, RpS21
Organism: Drosophila melanogaster
Interactions: 193
UniProt ID: O76927

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000461 - endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005791 - rough endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

304598

RSSA
Small ribosomal subunit protein uS2

1

15

Small-scale

0.618

High

304751

RAE1
Protein Rae1

2

0

High-throughput

0.547

High

53747

A1Z850
Superoxide dismutase [Cu-Zn]

2

2

High-throughput

0.521

High

304589

NDKA
Nucleoside diphosphate kinase

2

1

High-throughput

0.521

High

304602

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

2

3

High-throughput

0.521

High

304627

GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta

2

1

High-throughput

0.521

High

304657

Q9I7N2
Nucleoporin NUP42

2

1

High-throughput

0.521

High

304666

THIO2
Thioredoxin-2

2

1

High-throughput

0.521

High

304690

Q9VGK3
peptidylprolyl isomerase

2

3

High-throughput

0.521

High

304691

Q9VGQ4
Venom allergen-1

1

1

High-throughput

0.464

High

304710

Q9VMS5
Bub1 kinase, isoform A

1

1

High-throughput

0.464

High

304606

PDI
Protein disulfide-isomerase

1

2

High-throughput

0.445

High

304738

RS10B
Small ribosomal subunit protein eS10B

1

2

High-throughput

0.445

High

304648

Q8T3W8
Venom allergen-1

1

1

High-throughput

0.439

High

304588

TRYA
Trypsin alpha

1

1

High-throughput

0.437

High

304608

SODC
Superoxide dismutase [Cu-Zn]

1

2

High-throughput

0.437

High

304613

FTF1B
Nuclear hormone receptor FTZ-F1 beta

1

1

High-throughput

0.437

High

304638

Q8IRS7
Ciboulot, isoform C

1

1

High-throughput

0.437

High

304658

Q9I7N3
Nucleoporin NUP42

1

1

High-throughput

0.437

High

304743

Q9VYR1
Regucalcin

1

1

High-throughput

0.437

High

304649

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.426

High

304654

IF5A
Eukaryotic translation initiation factor 5A

1

0

High-throughput

0.426

High

304745

ETIF1
Eukaryotic translation initiation factor eIF1

1

0

High-throughput

0.426

High

53949

A1Z892
1-Cys peroxiredoxin

1

1

High-throughput

0.407

High

57497

A1ZB71
Glutathione S transferase E6

1

2

High-throughput

0.407

High

121157

ALDR
Aldo-keto reductase 1B

1

5

High-throughput

0.407

High

304585

O97102
Small ubiquitin-related modifier

1

2

High-throughput

0.407

High

304586

O97428
Ciboulot, isoform A

1

1

High-throughput

0.407

High

304587

INO1
Inositol-3-phosphate synthase

1

1

High-throughput

0.407

High

304597

UCHL
Ubiquitin carboxyl-terminal hydrolase

1

1

High-throughput

0.407

High

304601

MOEH
Moesin/ezrin/radixin homolog 1

1

1

High-throughput

0.407

High

304604

TRYI
Trypsin iota

1

1

High-throughput

0.407

High

304610

TRXR1
Thioredoxin reductase 1, mitochondrial

1

1

High-throughput

0.407

High

304611

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.407

High

304614

HMGD
High mobility group protein D

1

2

High-throughput

0.407

High

304618

NLP
Nucleoplasmin-like protein

1

2

High-throughput

0.407

High

304620

Q3YMU0
Protein disulfide-isomerase

1

1

High-throughput

0.407

High

304621

Q76NR6
Regucalcin

1

1

High-throughput

0.407

High

304623

Q7JVH6
LD24696p

1

5

High-throughput

0.407

High

304624

Q7JX87
1-Cys peroxiredoxin

1

1

High-throughput

0.407

High

304632

TERA
Transitional endoplasmic reticulum ATPase TER94

1

1

High-throughput

0.407

High

304641

Q8MYY7
RE44624p

1

2

High-throughput

0.407

High

304643

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.407

High

304644

Q8SXQ9
Glutathione S transferase D11, isoform A

1

2

High-throughput

0.407

High

304650

ACPM
Acyl carrier protein, mitochondrial

1

1

High-throughput

0.407

High

304663

Q9V3V2
peptidylprolyl isomerase

1

3

High-throughput

0.407

High

304667

PDIA6
Protein disulfide-isomerase A6 homolog

1

1

High-throughput

0.407

High

304668

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.407

High

304669

FBSP1
F-box/SPRY domain-containing protein 1

1

1

High-throughput

0.407

High

304674

Q9VAC4
GEO09167p1

1

2

High-throughput

0.407

High

304678

Q9VAY2
Heat shock protein 83

1

1

High-throughput

0.407

High

304688

Q9VFV9
DnaJ-like-2, isoform A

1

1

High-throughput

0.407

High

304693

TEBPH
Cytosolic Prostaglandin E synthase

1

1

High-throughput

0.407

High

304696

Q9VHX4
LD24679p

1

5

High-throughput

0.407

High

304704

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

1

1

High-throughput

0.407

High

304706

FKB59
FK506-binding protein 59

1

2

High-throughput

0.407

High

304713

PSB4
Proteasome subunit beta type-4

1

1

High-throughput

0.407

High

304722

Q9VRD6
NTF2-related export protein

1

4

High-throughput

0.407

High

304724

Q9VRP2
Uncharacterized protein, isoform A

1

1

High-throughput

0.407

High

304725

Q9VSL2
Glutathione S transferase O3

1

1

High-throughput

0.407

High

304727

Q9VTY2
Uncharacterized protein, isoform A

1

5

High-throughput

0.407

High

304734

Q9VVL7
Dihydrolipoyl dehydrogenase

1

1

High-throughput

0.407

High

304741

CLIC
Chloride intracellular channel Clic

1

1

High-throughput

0.407

High

304744

Q9VZI1
Transgelin

1

1

High-throughput

0.407

High

304746

Q9W022
GEO01508p1

1

2

High-throughput

0.407

High

304756

WUHO
tRNA

1

1

High-throughput

0.407

High

304759

PSB3
Proteasome subunit beta type-3

1

1

High-throughput

0.407

High

304760

Q9XYZ9
Glutathione S transferase E12, isoform A

1

2

High-throughput

0.407

High

304761

Q9XZ57
Eb1, isoform E

1

1

High-throughput

0.407

High

304762

PSA6
Proteasome subunit alpha type-6

1

2

High-throughput

0.407

High

304763

PURA
Adenylosuccinate synthetase

1

1

High-throughput

0.407

High

304764

Q9Y112
BcDNA.GH10614

1

5

High-throughput

0.407

High

56503

A1ZAA5
Aspartate aminotransferase, cytoplasmic

2

0

High-throughput

0.298

High

304630

ARC1
Activity-regulated cytoskeleton associated protein 1

2

0

High-throughput

0.298

High

304660

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

2

0

High-throughput

0.298

High

304721

Q9VRD4
Uncharacterized protein, isoform A

2

0

High-throughput

0.298

High

304732

Q9VUU7
Zinc finger protein 706

2

0

High-throughput

0.298

High

304742

BTHD
Selenoprotein BthD

2

0

High-throughput

0.298

High

304749

Q9W0U6
Sulfatase-modifying factor enzyme-like domain-containing protein

2

0

High-throughput

0.298

High

56613

A1ZAC8
Uncharacterized protein, isoform B

1

0

High-throughput

0.265

Low

304609

SMO
Protein smoothened

1

0

High-throughput

0.265

Low

304616

Q0E8X9
FI08136p

1

0

High-throughput

0.265

Low

304619

Q29R10
LD24322p

1

0

High-throughput

0.265

Low

304622

Q7JV69
SD11922p

1

0

High-throughput

0.265

Low

304628

Q7JZD5
Dorsal interacting protein 3

1

0

High-throughput

0.265

Low

304677

DGT6
Augmin complex subunit dgt6

1

0

High-throughput

0.265

Low

304687

Q9VFH4
LD12755p

1

0

High-throughput

0.265

Low

304694

Q9VHG0
Heterochromatin protein 1e

1

0

High-throughput

0.265

Low

304699

SIRT1
NAD-dependent histone deacetylase sirtuin-1

1

0

High-throughput

0.265

Low

304709

Q9VLR0
FI06011p

1

0

High-throughput

0.265

Low

304726

Q9VT02
Chitin-binding type-2 domain-containing protein

1

0

High-throughput

0.265

Low

304735

Q9VVY2
Uncharacterized protein

1

0

High-throughput

0.265

Low

68828

APLF
Aprataxin and PNK-like factor

1

0

High-throughput

0.249

Low

304594

HSF
Heat shock factor protein

1

0

High-throughput

0.249

Low

304639

Q8MKJ6
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.249

Low

304646

Q8SYR5
GEO07715p1

1

0

High-throughput

0.249

Low

304651

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

0

High-throughput

0.249

Low

304653

PGPLC
Peptidoglycan-recognition protein LC

1

0

High-throughput

0.249

Low

304670

Q9V9Q6
AT16263p

1

0

High-throughput

0.249

Low

304701

ZUC
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

304708

WDR82
WD repeat-containing protein 82

1

0

High-throughput

0.249

Low

304712

Q9VMU7
FI16614p1

1

0

High-throughput

0.249

Low

304715

HPF1
Histone PARylation factor 1-like

1

0

High-throughput

0.249

Low

304719

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

0

High-throughput

0.249

Low

304730

PYRG
CTP synthase

1

0

High-throughput

0.249

Low

304752

TREA
Trehalase

1

0

High-throughput

0.249

Low

57727

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.232

Low

86440

B9EQV3
Endoplasmic reticulum transmembrane protein

1

0

High-throughput

0.232

Low

194979

O16043
Anon1A4

1

0

High-throughput

0.232

Low

197710

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.232

Low

304583

TRMB
tRNA

1

0

High-throughput

0.232

Low

304584

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.232

Low

304590

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.232

Low

304591

ENO
Enolase

1

0

High-throughput

0.232

Low

304592

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.232

Low

304593

ANX10
Annexin B10

1

0

High-throughput

0.232

Low

304595

PROF
Profilin

1

0

High-throughput

0.232

Low

304596

CALR
Calreticulin

1

0

High-throughput

0.232

Low

304599

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.232

Low

304600

PNUT
Protein peanut

1

0

High-throughput

0.232

Low

304603

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

High-throughput

0.232

Low

304605

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

0

High-throughput

0.232

Low

304607

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

304612

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.232

Low

304615

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

304617

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.232

Low

304625

Q7JX94
Phospholipase A2

1

0

High-throughput

0.232

Low

304626

Q7JXC4
CG6459 protein

1

0

High-throughput

0.232

Low

304629

Q7K148
Proteasome subunit beta

1

0

High-throughput

0.232

Low

304631

Q7K2K2
FI04612p

1

0

High-throughput

0.232

Low

304633

Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A

1

0

High-throughput

0.232

Low

304634

Q7KTW5
Inositol-1-monophosphatase

1

0

High-throughput

0.232

Low

304635

Q8INK3
Fatty acid-binding protein, muscle

1

0

High-throughput

0.232

Low

304636

Q8IQZ7
FI19014p1

1

0

High-throughput

0.232

Low

304637

Q8IRD3
Glutathione peroxidase

1

0

High-throughput

0.232

Low

304640

Q8MT58
Carnosine dipeptidase 2, isoform A

1

0

High-throughput

0.232

Low

304642

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

1

0

High-throughput

0.232

Low

304645

Q8SY49
GH17676p

1

0

High-throughput

0.232

Low

304647

Q8T0L3
E1 ubiquitin-activating enzyme

1

0

High-throughput

0.232

Low

304652

FAXC
Failed axon connections

1

0

High-throughput

0.232

Low

304655

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.232

Low

304656

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.232

Low

304659

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.232

Low

304661

CP2B
Cardio acceleratory peptide 2b

1

0

High-throughput

0.232

Low

304662

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.232

Low

304664

SPC25
Kinetochore protein Spc25

1

0

High-throughput

0.232

Low

304665

Q9V3V9
Endonuclease G inhibitor, isoform A

1

0

High-throughput

0.232

Low

304671

Q9V9U3
LD45254p

1

0

High-throughput

0.232

Low

304672

Q9VA42
Niemann-Pick type C-2g, isoform A

1

0

High-throughput

0.232

Low

304673

Q9VAC1
GM14349p

1

0

High-throughput

0.232

Low

304675

Q9VAD7
RH37294p

1

0

High-throughput

0.232

Low

304676

Q9VAN7
Phosphoglycerate mutase

1

0

High-throughput

0.232

Low

304679

Q9VBR6
RE74917p

1

0

High-throughput

0.232

Low

304680

Q9VBT1
CHK kinase-like domain-containing protein

1

0

High-throughput

0.232

Low

304681

Q9VCK6
LD34157p

1

0

High-throughput

0.232

Low

304682

Q9VD02
GH14779p

1

0

High-throughput

0.232

Low

304683

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

High-throughput

0.232

Low

304684

Q9VD29
small monomeric GTPase

1

0

High-throughput

0.232

Low

304685

Q9VEB1
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

304686

FLNA
Filamin-A

1

0

High-throughput

0.232

Low

304689

Q9VG33
Sulfurtransferase

1

0

High-throughput

0.232

Low

304692

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.232

Low

304695

Q9VHN7
transketolase

1

0

High-throughput

0.232

Low

304697

Q9VIE8
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.232

Low

304698

EFHD2
EF-hand domain-containing protein D2 homolog

1

0

High-throughput

0.232

Low

304700

Q9VKB0
threonine--tRNA ligase

1

0

High-throughput

0.232

Low

304702

Q9VKW5
Prolyl endopeptidase

1

0

High-throughput

0.232

Low

304703

EF1D
Probable elongation factor 1-delta

1

0

High-throughput

0.232

Low

304705

Q9VL70
HL08109p

1

0

High-throughput

0.232

Low

304707

AK200
A-kinase anchor protein 200

1

0

High-throughput

0.232

Low

304711

Q9VMU6
LD31822p

1

0

High-throughput

0.232

Low

304714

Q9VNB2
RE42193p

1

0

High-throughput

0.232

Low

304716

Q9VP52
GH24315p

1

0

High-throughput

0.232

Low

304717

Q9VPN5
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.232

Low

304718

Q9VPX6
Adenylyl cyclase-associated protein

1

0

High-throughput

0.232

Low

304720

BACC
Bacchus

1

0

High-throughput

0.232

Low

304723

Q9VRL1
GEO06356p1

1

0

High-throughput

0.232

Low

304728

Q9VU35
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.232

Low

304729

Q9VUC1
Hsc70Cb, isoform A

1

0

High-throughput

0.232

Low

304731

Q9VUR4
FI11905p

1

0

High-throughput

0.232

Low

304733

Y9705
Cold shock domain-containing protein CG9705

1

0

High-throughput

0.232

Low

304736

Q9VW59
Rho GDP-dissociation inhibitor 3

1

0

High-throughput

0.232

Low

304737

Q9VW70
FI21813p1

1

0

High-throughput

0.232

Low

304739

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

High-throughput

0.232

Low

304740

Q9VXQ3
Diphosphomevalonate decarboxylase

1

0

High-throughput

0.232

Low

304747

Q9W0H8
Reticulocalbin-3

1

0

High-throughput

0.232

Low

304748

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.232

Low

304750

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.232

Low

304753

Q9W3X6
fumarate hydratase

1

0

High-throughput

0.232

Low

304754

Q9W3Y3
Calcyclin-binding protein

1

0

High-throughput

0.232

Low

304755

CISY
Probable citrate synthase, mitochondrial

1

0

High-throughput

0.232

Low

304757

Q9W457
Serine hydroxymethyltransferase

1

0

High-throughput

0.232

Low

304758

Q9W478
RE43153p

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025