Protein: KMT5C
Histone-lysine N-methyltransferase KMT5C (Lysine N-methyltransferase 5C) (Lysine-specific methyltransferase 5C) (Suppressor of variegation 4-20 homolog 2) (Su(var)4-20 homolog 2) (Suv4-20h2) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.361)

Gene: KMT5C
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q86Y97

Gene Ontology (top 5):
GO:0000779 - condensed chromosome, centromeric region
GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1250012

WDR82
WD repeat-containing protein 82

1

1

High-throughput

0.691

High

1097405

CBX3
Chromobox protein homolog 3

3

3

Small-scale

0.667

High

979932

H4
Histone H4

1

5

Small-scale

0.647

High

853331

CBX5
Chromobox protein homolog 5

2

3

Small-scale

0.624

High

1014151

CBX1
Chromobox protein homolog 1

2

3

Small-scale

0.624

High

1294904

POC1B
POC1 centriolar protein homolog B

1

0

High-throughput

0.578

High

129761

CBX4
E3 SUMO-protein ligase CBX4

1

3

High-throughput

0.536

High

1294903

FA76A
Protein FAM76A

1

1

High-throughput

0.536

High

160190

CHD2
Chromodomain-helicase-DNA-binding protein 2

1

0

High-throughput

0.513

High

212273

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

High-throughput

0.513

High

318507

TOX4
TOX high mobility group box family member 4

1

0

High-throughput

0.513

High

430102

JUN
Transcription factor Jun

1

0

High-throughput

0.513

High

542105

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

978598

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

1109166

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.513

High

1144403

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.513

High

1271721

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.513

High

1277841

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.513

High

1294906

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.513

High

1294907

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

0

High-throughput

0.513

High

1294909

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.513

High

1294911

S30BP
SAP30-binding protein

1

0

High-throughput

0.513

High

1294912

CCNL1
Cyclin-L1

1

0

High-throughput

0.513

High

1294908

H4G
Histone H4-like protein type G

1

5

Small-scale

0.501

High

1205069

FA76B
Protein FAM76B

1

1

High-throughput

0.489

High

756255

MCM7
DNA replication licensing factor MCM7

1

0

Small-scale

0.458

High

761747

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

861670

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

Small-scale

0.458

High

879245

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

897160

TUB
Tubby protein homolog

1

0

Small-scale

0.458

High

996227

EF1A1
Elongation factor 1-alpha 1

1

0

Small-scale

0.458

High

1005907

GTF2I
General transcription factor II-I

1

0

Small-scale

0.458

High

1294910

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

0

Small-scale

0.458

High

391328

FRIL
Ferritin light chain

2

0

High-throughput

0.313

High

649741

SPR1B
Cornifin-B

1

0

High-throughput

0.279

Low

868550

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.279

Low

1162729

QPCT
Glutaminyl-peptide cyclotransferase

1

0

High-throughput

0.279

Low

1294905

ATX2L
Ataxin-2-like protein

1

0

High-throughput

0.279

Low

58854

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025