Protein: CCNL1
Cyclin-L1 (Cyclin-L)

Gene: CCNL1
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9UK58

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity
GO:0016607 - nuclear speck

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1460929

CD11A
Cyclin-dependent kinase 11A

6

20

Small-scale

0.939

High

625696

CSK22
Casein kinase II subunit alpha'

4

20

High-throughput

0.900

High

998099

CSK21
Casein kinase II subunit alpha

4

20

Small-scale

0.892

High

636161

CD11B
Cyclin-dependent kinase 11B

2

20

High-throughput

0.776

High

1239691

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

4

2

High-throughput

0.697

High

1145429

RNPS1
RNA-binding protein with serine-rich domain 1

4

3

High-throughput

0.689

High

1460068

S30BP
SAP30-binding protein

4

1

High-throughput

0.689

High

280864

PR40A
Pre-mRNA-processing factor 40 homolog A

3

7

High-throughput

0.660

High

1459248

ZRAN1
Ubiquitin thioesterase ZRANB1

3

8

High-throughput

0.653

High

995339

CSK2B
Casein kinase II subunit beta

3

3

High-throughput

0.650

High

897424

CDK7
Cyclin-dependent kinase 7

1

20

High-throughput

0.618

High

250361

VINEX
Vinexin

2

5

High-throughput

0.606

High

1420992

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

3

High-throughput

0.601

High

998929

H31
Histone H3.1

2

2

High-throughput

0.584

High

292403

RA51D
DNA repair protein RAD51 homolog 4

2

0

High-throughput

0.580

High

1414734

RSRP1
Arginine/serine-rich protein 1

2

0

High-throughput

0.580

High

1447535

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

0

High-throughput

0.580

High

1337851

CSK23
Casein kinase II subunit alpha 3

1

20

High-throughput

0.575

High

1365999

APBP2
Amyloid protein-binding protein 2

1

3

High-throughput

0.573

High

397180

ESR1
Estrogen receptor

2

19

High-throughput

0.571

High

948403

KR122
Keratin-associated protein 12-2

2

2

High-throughput

0.553

High

1371472

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

2

High-throughput

0.553

High

1414009

MMTA2
Multiple myeloma tumor-associated protein 2

2

1

High-throughput

0.553

High

1458240

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.549

High

481408

HMGB1
High mobility group protein B1

1

8

High-throughput

0.536

High

1380241

FBXW7
F-box/WD repeat-containing protein 7

1

2

Small-scale

0.527

High

425671

ISG15
Ubiquitin-like protein ISG15

1

6

High-throughput

0.515

High

324060

CSTN1
Calsyntenin-1

1

2

High-throughput

0.515

High

1238960

Q6NVI2
CASP8 protein

1

1

High-throughput

0.515

High

1294912

KMT5C
Histone-lysine N-methyltransferase KMT5C

1

0

High-throughput

0.513

High

1405998

C10
Protein C10

1

0

High-throughput

0.513

High

1460928

PARP4
Protein mono-ADP-ribosyltransferase PARP4

1

0

High-throughput

0.513

High

1249871

BTNL9
Butyrophilin-like protein 9

1

4

High-throughput

0.489

High

1322389

PGAM4
Probable phosphoglycerate mutase 4

1

2

High-throughput

0.489

High

1408450

TEP1
Telomerase protein component 1

1

4

High-throughput

0.489

High

1132463

CASP8
Caspase-8

1

3

High-throughput

0.481

High

243246

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

320793

UBXN7
UBX domain-containing protein 7

1

1

High-throughput

0.479

High

326090

UBR5
E3 ubiquitin-protein ligase UBR5

1

8

High-throughput

0.479

High

343102

HERC2
E3 ubiquitin-protein ligase HERC2

1

6

High-throughput

0.479

High

414808

P53
Cellular tumor antigen p53

1

7

High-throughput

0.479

High

696818

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

935651

MFAP1
Microfibrillar-associated protein 1

1

1

High-throughput

0.479

High

986803

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

1005230

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

1017286

H33
Histone H3.3

1

2

High-throughput

0.479

High

1112775

CUL1
Cullin-1

1

3

Small-scale

0.479

High

1115133

CUL4A
Cullin-4A

1

3

Small-scale

0.479

High

1347758

FA76A
Protein FAM76A

1

1

High-throughput

0.479

High

1367546

ESR2
Estrogen receptor beta

1

19

High-throughput

0.479

High

562478

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.470

High

1460930

SHLB1
Endophilin-B1

1

4

High-throughput

0.470

High

1332859

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.458

High

47598

RPSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.445

High

1016665

SRSF3
Serine/arginine-rich splicing factor 3

1

15

Small-scale

0.445

High

1029572

SRSF2
Serine/arginine-rich splicing factor 2

1

6

Small-scale

0.445

High

1061202

SRSF1
Serine/arginine-rich splicing factor 1

1

14

Small-scale

0.445

High

1062148

SRSF4
Serine/arginine-rich splicing factor 4

1

11

Small-scale

0.445

High

1099299

SRSF5
Serine/arginine-rich splicing factor 5

1

13

Small-scale

0.445

High

1099594

SRSF6
Serine/arginine-rich splicing factor 6

1

15

Small-scale

0.445

High

1130512

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

1

High-throughput

0.445

High

1160121

SRSF7
Serine/arginine-rich splicing factor 7

1

14

Small-scale

0.445

High

769471

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

1256024

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1312339

MIRO1
Mitochondrial Rho GTPase 1

1

1

High-throughput

0.437

High

1005991

GTF2I
General transcription factor II-I

1

0

High-throughput

0.426

High

230137

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

High-throughput

0.407

High

1290419

LRRT4
Leucine-rich repeat transmembrane neuronal protein 4

1

2

High-throughput

0.407

High

1393332

SAHH3
Adenosylhomocysteinase 3

1

1

High-throughput

0.407

High

1152355

U2AFM
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

2

0

High-throughput

0.316

High

1256756

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.316

High

1331801

F133A
Protein FAM133A

2

0

High-throughput

0.316

High

1332162

SR1IP
Protein SREK1IP1

2

0

High-throughput

0.316

High

423427

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

1253012

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

287627

LRP6
Low-density lipoprotein receptor-related protein 6

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025