Protein: AXIN2
Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin)

Gene: AXIN2
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q9Y2T1

Gene Ontology (top 5):
GO:0001649 - osteoblast differentiation
GO:0001756 - somitogenesis
GO:0001934 - positive regulation of protein phosphorylation
GO:0001957 - intramembranous ossification
GO:0003139 - secondary heart field specification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

836105

GSK3B
Glycogen synthase kinase-3 beta

11

8

Small-scale

0.977

High

835575

GSK3A
Glycogen synthase kinase-3 alpha

4

7

High-throughput

0.902

High

717454

CTNB1
Catenin beta-1

4

8

Small-scale

0.867

High

1305985

BARD1
BRCA1-associated RING domain protein 1

2

8

High-throughput

0.783

High

1377155

FBW1A
F-box/WD repeat-containing protein 1A

2

4

High-throughput

0.783

High

170739

AXIN1
Axin-1

2

7

Small-scale

0.737

High

1329543

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

2

6

Small-scale

0.737

High

1377208

ANKR6
Ankyrin repeat domain-containing protein 6

1

10

Small-scale

0.713

High

1017471

CDC20
Cell division cycle protein 20 homolog

1

2

Small-scale

0.665

High

330167

APCL
Adenomatous polyposis coli protein 2

1

10

Small-scale

0.621

High

566509

KPCA
Protein kinase C alpha type

1

4

High-throughput

0.618

High

626297

APC
Adenomatous polyposis coli protein

1

12

Small-scale

0.618

High

861995

PLK1
Serine/threonine-protein kinase PLK1

1

3

Small-scale

0.618

High

1356373

FBW1B
F-box/WD repeat-containing protein 11

1

4

High-throughput

0.618

High

1377394

M3K2
Mitogen-activated protein kinase kinase kinase 2

1

6

Small-scale

0.618

High

269503

STX11
Syntaxin-11

2

3

High-throughput

0.606

High

447308

HXB5
Homeobox protein Hox-B5

2

8

High-throughput

0.606

High

770708

TXLNA
Alpha-taxilin

2

6

High-throughput

0.606

High

832182

PSB2
Proteasome subunit beta type-2

2

1

High-throughput

0.606

High

887749

KR10A
Keratin-associated protein 10-10

2

13

High-throughput

0.606

High

889731

KR108
Keratin-associated protein 10-8

2

12

High-throughput

0.606

High

1069278

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

2

2

High-throughput

0.606

High

1075193

TCEA2
Transcription elongation factor A protein 2

2

1

High-throughput

0.606

High

1080852

ZN124
Zinc finger protein 124

2

2

High-throughput

0.606

High

1133873

ZN648
Zinc finger protein 648

2

1

High-throughput

0.606

High

1232457

TXLNB
Beta-taxilin

2

10

High-throughput

0.606

High

1237661

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

2

High-throughput

0.606

High

1251807

ZN417
Zinc finger protein 417

2

2

High-throughput

0.606

High

1252559

LNX1
E3 ubiquitin-protein ligase LNX

2

7

High-throughput

0.606

High

1302392

ZN587
Zinc finger protein 587

2

2

High-throughput

0.606

High

1313816

KIFC3
Kinesin-like protein KIFC3

2

7

High-throughput

0.606

High

1317285

KRA92
Keratin-associated protein 9-2

2

12

High-throughput

0.606

High

1317320

KRA45
Keratin-associated protein 4-5

2

12

High-throughput

0.606

High

1318468

TSG10
Testis-specific gene 10 protein

2

5

High-throughput

0.606

High

1345817

RN146
E3 ubiquitin-protein ligase RNF146

2

1

Small-scale

0.601

High

915309

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

5

Small-scale

0.598

High

167412

SMAD7
Mothers against decapentaplegic homolog 7

2

6

Small-scale

0.595

High

271982

CTAG2
Cancer/testis antigen 2

2

0

High-throughput

0.580

High

329011

TOP3B
DNA topoisomerase 3-beta-1

2

0

High-throughput

0.580

High

1047011

BYST
Bystin

2

0

High-throughput

0.580

High

1107965

F161A
Protein FAM161A

2

0

High-throughput

0.580

High

1243154

CC112
Coiled-coil domain-containing protein 112

2

0

High-throughput

0.580

High

1290789

MCRS1
Microspherule protein 1

2

0

High-throughput

0.580

High

1314700

SCNM1
Sodium channel modifier 1

2

0

High-throughput

0.580

High

1315730

AP1M1
AP-1 complex subunit mu-1

2

0

High-throughput

0.580

High

1356467

CHIC2
Cysteine-rich hydrophobic domain-containing protein 2

2

0

High-throughput

0.580

High

1377396

CAN7
Calpain-7

2

0

High-throughput

0.580

High

310109

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

6

Small-scale

0.575

High

1052048

ELOA1
Elongin-A

2

2

High-throughput

0.553

High

135908

F16P2
Fructose-1,6-bisphosphatase isozyme 2

1

1

High-throughput

0.541

High

450963

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.541

High

843973

FXR1
RNA-binding protein FXR1

1

3

High-throughput

0.541

High

844294

FXR2
RNA-binding protein FXR2

1

3

High-throughput

0.541

High

1078781

SMAD1
Mothers against decapentaplegic homolog 1

1

6

High-throughput

0.541

High

1238024

AMER3
APC membrane recruitment protein 3

1

1

Small-scale

0.536

High

275756

ZN189
Zinc finger protein 189

1

0

High-throughput

0.518

High

351477

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.518

High

801800

RAGP1
Ran GTPase-activating protein 1

1

0

High-throughput

0.518

High

989416

PRDX1
Peroxiredoxin-1

1

0

High-throughput

0.518

High

1335064

KCNKC
Potassium channel subfamily K member 12

1

0

High-throughput

0.518

High

1274485

H2B1H
Histone H2B type 1-H

1

3

High-throughput

0.515

High

57701

A2BDD9
AMOT protein

1

5

High-throughput

0.515

High

1119103

AMOT
Angiomotin

1

4

High-throughput

0.481

High

1075368

TGIF1
Homeobox protein TGIF1

1

1

Small-scale

0.481

High

611528

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

3

Small-scale

0.479

High

1169202

RN111
E3 ubiquitin-protein ligase Arkadia

1

3

Small-scale

0.479

High

1216736

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

2

Small-scale

0.479

High

1345428

KIF15
Kinesin-like protein KIF15

1

7

Small-scale

0.479

High

1346939

RNF12
E3 ubiquitin-protein ligase RLIM

1

4

Small-scale

0.479

High

1377395

AMMR1
Nuclear protein AMMECR1

1

1

Small-scale

0.479

High

1355125

KDM5B
Lysine-specific demethylase 5B

1

0

Small-scale

0.458

High

1102087

CB068
UPF0561 protein C2orf68

2

0

High-throughput

0.316

High

1103282

C19L2
CWF19-like protein 2

2

0

High-throughput

0.316

High

1315456

HEMGN
Hemogen

1

0

High-throughput

0.282

High


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Last updated: 15 Jul 2024