Protein: AK1C1
Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (EC 1.1.1.112) (EC 1.1.1.209) (EC 1.1.1.210) (EC 1.1.1.357) (EC 1.1.1.51) (EC 1.1.1.53) (EC 1.1.1.62) (EC 1.3.1.20) (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (EC 1.1.1.149) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1) (DD1) (High-affinity hepatic bile acid-binding protein) (HBAB)

Gene: AK1C1, AKR1C1
Organism: Homo sapiens
Interactions: 19
UniProt ID: Q04828

Gene Ontology (top 5):
GO:0001523 - retinoid metabolic process
GO:0004032 - aldose reductase (NADPH) activity
GO:0004033 - aldo-keto reductase (NADPH) activity
GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

787132

AK1C3
Aldo-keto reductase family 1 member C3

3

11

High-throughput

0.861

High

857069

AK1C2
Aldo-keto reductase family 1 member C2

3

11

High-throughput

0.861

High

850867

AK1D1
Aldo-keto reductase family 1 member D1

3

11

High-throughput

0.848

High

640236

PTN3
Tyrosine-protein phosphatase non-receptor type 3

3

0

High-throughput

0.646

High

329664

AGR2
Anterior gradient protein 2 homolog

2

3

Small-scale

0.533

High

363097

FINC
Fibronectin

1

0

High-throughput

0.513

High

647551

MK03
Mitogen-activated protein kinase 3

1

1

High-throughput

0.508

High

981207

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

981208

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.489

High

981209

COMD8
COMM domain-containing protein 8

1

0

High-throughput

0.486

High

374089

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

874851

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

961063

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

981210

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

128843

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

2

High-throughput

0.445

High

496896

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

244324

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.437

High

981206

TFF3
Trefoil factor 3

1

0

Small-scale

0.288

High

981211

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024