Protein: TRFR
Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberin receptor)

Gene: TRFR, TRHR
Organism: Homo sapiens
Interactions: 22
UniProt ID: P34981

Gene Ontology (top 5):
GO:0004997 - thyrotropin-releasing hormone receptor activity
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007200 - phospholipase C-activating G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

762177

TRFR
Thyrotropin-releasing hormone receptor

1

17

Small-scale

0.618

High

706012

CXB2
Gap junction beta-2 protein

2

6

High-throughput

0.606

High

762179

NIPA4
Magnesium transporter NIPA4

2

1

High-throughput

0.606

High

762181

S41A1
Solute carrier family 41 member 1

2

3

High-throughput

0.606

High

762186

S39A2
Zinc transporter ZIP2

2

6

High-throughput

0.606

High

762187

S39A9
Zinc transporter ZIP9

2

6

High-throughput

0.606

High

536241

PPAL
Lysosomal acid phosphatase

3

1

High-throughput

0.604

High

642204

COMT
Catechol O-methyltransferase

2

0

High-throughput

0.580

High

762178

EFNA5
Ephrin-A5

2

0

High-throughput

0.580

High

60557

TM218
Transmembrane protein 218

2

1

High-throughput

0.553

High

762180

C1QL4
Complement C1q-like protein 4

2

1

High-throughput

0.553

High

762183

F241B
Protein FAM241B

2

1

High-throughput

0.553

High

762184

YIPF6
Protein YIPF6

2

1

High-throughput

0.553

High

762188

TEFF2
Tomoregulin-2

2

2

High-throughput

0.553

High

762189

UB2J1
Ubiquitin-conjugating enzyme E2 J1

2

1

High-throughput

0.553

High

116727

I3L0A0
HCG2044781

1

1

High-throughput

0.470

High

762185

FXYD6
FXYD domain-containing ion transport regulator 6

1

0

High-throughput

0.460

High

63815

PEDS1
Plasmanylethanolamine desaturase 1

1

1

High-throughput

0.439

High

762182

TM239
Transmembrane protein 239

2

0

High-throughput

0.316

High

762190

IR3IP
Immediate early response 3-interacting protein 1

2

0

High-throughput

0.316

High

338779

CBX6
Chromobox protein homolog 6

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025