Protein: AP1B1
AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)

Gene: AP1B1
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q10567

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001822 - kidney development
GO:0005765 - lysosomal membrane
GO:0005769 - early endosome
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1014061

AP2M1
AP-2 complex subunit mu

7

20

Small-scale

0.964

High

212624

AP1G1
AP-1 complex subunit gamma-1

6

14

Small-scale

0.938

High

1014091

NECP2
Adaptin ear-binding coat-associated protein 2

4

12

High-throughput

0.903

High

880409

AP1S2
AP-1 complex subunit sigma-2

3

20

High-throughput

0.871

High

1014107

AP1M2
AP-1 complex subunit mu-2

3

20

High-throughput

0.861

High

1014074

AP1M1
AP-1 complex subunit mu-1

3

20

Small-scale

0.849

High

864070

AP2S1
AP-2 complex subunit sigma

2

20

High-throughput

0.811

High

276366

AP1G2
AP-1 complex subunit gamma-like 2

2

13

High-throughput

0.793

High

925858

AP2B1
AP-2 complex subunit beta

2

12

High-throughput

0.789

High

1014052

NECP1
Adaptin ear-binding coat-associated protein 1

2

12

High-throughput

0.783

High

1014011

EPN4
Clathrin interactor 1

4

20

Small-scale

0.696

High

302144

AP2A2
AP-2 complex subunit alpha-2

1

13

High-throughput

0.691

High

321535

AP2A1
AP-2 complex subunit alpha-1

1

13

High-throughput

0.691

High

903682

AP1S1
AP-1 complex subunit sigma-1A

1

20

High-throughput

0.691

High

1014058

STON2
Stonin-2

1

20

High-throughput

0.691

High

1014066

AP1S3
AP-1 complex subunit sigma-3

1

20

High-throughput

0.691

High

1014078

KI13A
Kinesin-like protein KIF13A

3

11

Small-scale

0.675

High

338339

EGFR
Epidermal growth factor receptor

3

12

High-throughput

0.671

High

827743

AMPH
Amphiphysin

3

20

Small-scale

0.670

High

787903

EPS15
Epidermal growth factor receptor substrate 15

3

20

Small-scale

0.667

High

1014041

Q86V28
AP-1 complex subunit gamma

1

16

High-throughput

0.665

High

950481

ARF1
ADP-ribosylation factor 1

1

20

Small-scale

0.647

High

960765

CLH1
Clathrin heavy chain 1

1

11

Small-scale

0.647

High

257175

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

2

12

High-throughput

0.628

High

1014024

RUN3A
RUN domain-containing protein 3A

2

5

High-throughput

0.628

High

1014050

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

2

10

High-throughput

0.628

High

1014104

SNX9
Sorting nexin-9

2

6

High-throughput

0.628

High

912875

ARF6
ADP-ribosylation factor 6

1

20

High-throughput

0.618

High

451428

CLCA
Clathrin light chain A

2

13

High-throughput

0.611

High

1014021

AAK1
AP2-associated protein kinase 1

2

19

High-throughput

0.611

High

1014029

CC183
Coiled-coil domain-containing protein 183

3

8

High-throughput

0.609

High

1014028

ARH
Low density lipoprotein receptor adapter protein 1

2

20

High-throughput

0.606

High

1014055

AGR3
Anterior gradient protein 3

2

6

High-throughput

0.606

High

529041

CFTR
Cystic fibrosis transmembrane conductance regulator

2

3

High-throughput

0.601

High

833587

NUMB
Protein numb homolog

2

20

Small-scale

0.601

High

227287

PRKN
E3 ubiquitin-protein ligase parkin

2

16

High-throughput

0.584

High

591830

RAB4A
Ras-related protein Rab-4A

2

5

High-throughput

0.584

High

1014043

LSR
Lipolysis-stimulated lipoprotein receptor

2

2

High-throughput

0.574

High

1014053

GP156
Probable G-protein coupled receptor 156

2

2

High-throughput

0.574

High

1014084

GPBL1
Vasculin-like protein 1

2

2

High-throughput

0.574

High

1014089

BMP2K
BMP-2-inducible protein kinase

2

17

High-throughput

0.558

High

63046

MSGN1
Mesogenin-1

2

1

High-throughput

0.553

High

327063

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

6

High-throughput

0.553

High

776304

MLH1
DNA mismatch repair protein Mlh1

2

3

High-throughput

0.553

High

942147

GTF2I
General transcription factor II-I

2

1

High-throughput

0.553

High

963194

U2AF1
Splicing factor U2AF 35 kDa subunit

2

2

High-throughput

0.553

High

1014039

NUP54
Nucleoporin p54

2

3

High-throughput

0.553

High

1014064

P121A
Nuclear envelope pore membrane protein POM 121

2

5

High-throughput

0.553

High

1014079

RNF39
RING finger protein 39

2

1

High-throughput

0.553

High

1014100

PS1C2
Psoriasis susceptibility 1 candidate gene 2 protein

2

1

High-throughput

0.553

High

496926

TAU
Microtubule-associated protein tau

2

17

High-throughput

0.552

High

1014018

NTRK2
BDNF/NT-3 growth factors receptor

1

14

High-throughput

0.541

High

1014007

ATM
Serine-protein kinase ATM

1

5

Small-scale

0.536

High

147154

FCHO1
F-BAR domain only protein 1

1

10

High-throughput

0.536

High

203223

SYNJ1
Synaptojanin-1

1

9

High-throughput

0.536

High

255316

HIP1R
Huntingtin-interacting protein 1-related protein

1

5

High-throughput

0.536

High

451671

CLCB
Clathrin light chain B

1

11

High-throughput

0.536

High

602522

COMT
Catechol O-methyltransferase

1

2

High-throughput

0.536

High

666090

SHC1
SHC-transforming protein 1

1

17

High-throughput

0.536

High

957123

SHC2
SHC-transforming protein 2

1

17

High-throughput

0.536

High

1001572

FCHO2
F-BAR domain only protein 2

1

10

High-throughput

0.536

High

1014010

CUL3
Cullin-3

1

6

High-throughput

0.536

High

1014015

RNPS1
RNA-binding protein with serine-rich domain 1

1

6

High-throughput

0.536

High

1014016

RBP1
RalA-binding protein 1

1

11

High-throughput

0.536

High

1014017

ITSN1
Intersectin-1

1

20

High-throughput

0.536

High

1014034

AFTIN
Aftiphilin

1

2

High-throughput

0.536

High

1014060

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.536

High

1014062

REPS1
RalBP1-associated Eps domain-containing protein 1

1

20

High-throughput

0.536

High

1014063

STALP
AMSH-like protease

1

1

High-throughput

0.536

High

1014065

SPT33
Spermatogenesis-associated protein 33

1

1

High-throughput

0.536

High

1014071

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

15

High-throughput

0.536

High

1014076

WNK3
Serine/threonine-protein kinase WNK3

1

7

High-throughput

0.536

High

1014094

GTSE1
G2 and S phase-expressed protein 1

1

4

High-throughput

0.536

High

1014096

ITSN2
Intersectin-2

1

20

High-throughput

0.536

High

1014097

HTR5B
HEAT repeat-containing protein 5B

1

6

High-throughput

0.536

High

1014098

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

20

High-throughput

0.536

High

1014102

SYNRG
Synergin gamma

1

3

High-throughput

0.536

High

552582

RFA2
Replication protein A 32 kDa subunit

2

5

High-throughput

0.533

High

720322

RFA3
Replication protein A 14 kDa subunit

2

5

High-throughput

0.533

High

1014092

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

4

Small-scale

0.527

High

1014037

Q6ZN96
cDNA FLJ16308 fis, clone PUAEN2006335

1

3

High-throughput

0.515

High

1014101

FBX4
F-box only protein 4

1

0

High-throughput

0.513

High

609825

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

4

High-throughput

0.489

High

990423

CKAP4
Cytoskeleton-associated protein 4

1

6

High-throughput

0.489

High

1014009

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.489

High

1014019

MEA1
Male-enhanced antigen 1

1

2

High-throughput

0.489

High

1014022

INSY1
Inhibitory synaptic factor 1

1

2

High-throughput

0.489

High

1014026

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

11

High-throughput

0.489

High

1014054

ZCH10
Zinc finger CCHC domain-containing protein 10

1

2

High-throughput

0.489

High

1014069

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.489

High

1014082

PAAT
ATPase PAAT

1

1

High-throughput

0.489

High

331265

CHK2
Serine/threonine-protein kinase Chk2

1

4

Small-scale

0.484

High

1014067

FMNL2
Formin-like protein 2

1

3

High-throughput

0.481

High

132462

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

3

High-throughput

0.479

High

150965

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

8

High-throughput

0.479

High

162675

XPO1
Exportin-1

1

13

High-throughput

0.479

High

167905

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.479

High

205326

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.479

High

212810

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

237885

AP180
Clathrin coat assembly protein AP180

1

10

Small-scale

0.479

High

303196

HEXI1
Protein HEXIM1

1

7

High-throughput

0.479

High

308652

KI20A
Kinesin-like protein KIF20A

1

17

High-throughput

0.479

High

374123

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.479

High

377279

GCR
Glucocorticoid receptor

1

14

High-throughput

0.479

High

384728

NTRK1
High affinity nerve growth factor receptor

1

12

High-throughput

0.479

High

386618

P53
Cellular tumor antigen p53

1

3

High-throughput

0.479

High

417251

ENOA
Alpha-enolase

1

2

High-throughput

0.479

High

503976

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

527429

LAMP2
Lysosome-associated membrane glycoprotein 2

1

8

High-throughput

0.479

High

684665

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

685925

ARRB2
Beta-arrestin-2

1

9

Small-scale

0.479

High

742260

SYUA
Alpha-synuclein

1

3

Small-scale

0.479

High

835704

GSK3B
Glycogen synthase kinase-3 beta

1

2

High-throughput

0.479

High

874869

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

914034

RB11A
Ras-related protein Rab-11A

1

3

High-throughput

0.479

High

918319

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

925231

RAC1
Ras-related C3 botulinum toxin substrate 1

1

8

High-throughput

0.479

High

965649

IFM3
Interferon-induced transmembrane protein 3

1

8

High-throughput

0.479

High

998610

EP300
Histone acetyltransferase p300

1

12

High-throughput

0.479

High

1014013

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1014014

KIF14
Kinesin-like protein KIF14

1

11

High-throughput

0.479

High

1014020

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1014025

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

14

High-throughput

0.479

High

1014030

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

1014031

LTOR1
Ragulator complex protein LAMTOR1

1

5

High-throughput

0.479

High

1014040

ATG9A
Autophagy-related protein 9A

1

5

High-throughput

0.479

High

1014044

SLX4
Structure-specific endonuclease subunit SLX4

1

10

High-throughput

0.479

High

1014048

RHG18
Rho GTPase-activating protein 18

1

9

High-throughput

0.479

High

1014056

SMAP2
Stromal membrane-associated protein 2

1

9

High-throughput

0.479

High

1014057

PDC6I
Programmed cell death 6-interacting protein

1

11

High-throughput

0.479

High

1014059

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

1014086

BRD7
Bromodomain-containing protein 7

1

12

High-throughput

0.479

High

1014087

ANLN
Anillin

1

3

High-throughput

0.479

High

1014093

MTMR4
Myotubularin-related protein 4

1

4

High-throughput

0.479

High

1014095

TLS1
Splicing factor C9orf78

1

5

High-throughput

0.479

High

1014099

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1014103

LAMP3
Lysosome-associated membrane glycoprotein 3

1

8

High-throughput

0.479

High

1014105

EPN1
Epsin-1

1

20

Small-scale

0.479

High

1014106

CABIN
Calcineurin-binding protein cabin-1

1

2

Small-scale

0.479

High

825686

MTR1B
Melatonin receptor type 1B

1

2

High-throughput

0.464

High

625396

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

644244

TTP
mRNA decay activator protein ZFP36

1

0

High-throughput

0.458

High

1014068

CCNL2
Cyclin-L2

1

0

High-throughput

0.458

High

211006

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

10

Small-scale

0.457

High

236917

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

11

Small-scale

0.457

High

968133

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

9

High-throughput

0.445

High

1014027

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

7

High-throughput

0.445

High

1014032

PKHA7
Pleckstrin homology domain-containing family A member 7

1

17

High-throughput

0.445

High

1014077

ZDHC5
Palmitoyltransferase ZDHHC5

1

3

High-throughput

0.445

High

380955

SHBG
Sex hormone-binding globulin

1

2

Small-scale

0.439

High

1014070

BARD1
BRCA1-associated RING domain protein 1

1

6

High-throughput

0.439

High

146033

CLD4
Claudin-4

1

1

Small-scale

0.437

High

294761

RECQ4
ATP-dependent DNA helicase Q4

1

4

High-throughput

0.437

High

329682

AGR2
Anterior gradient protein 2 homolog

1

6

High-throughput

0.437

High

651054

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

670004

MARCS
Myristoylated alanine-rich C-kinase substrate

1

6

High-throughput

0.437

High

1014033

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

3

High-throughput

0.437

High

1014035

LMBRL
Protein LMBR1L

1

3

High-throughput

0.437

High

1014036

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.437

High

1014038

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1014042

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1014046

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.437

High

1014047

RHG24
Rho GTPase-activating protein 24

1

5

High-throughput

0.437

High

1014075

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.437

High

1014080

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.437

High

1014088

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.437

High

831266

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.408

High

944205

PRKDC
DNA-dependent protein kinase catalytic subunit

1

5

Small-scale

0.408

High

1014008

ATR
Serine/threonine-protein kinase ATR

1

5

Small-scale

0.408

High

401904

JUN
Transcription factor Jun

1

8

High-throughput

0.407

High

1014049

PNKD
Probable hydrolase PNKD

2

0

High-throughput

0.318

High

311915

SYFM
Phenylalanine--tRNA ligase, mitochondrial

2

0

High-throughput

0.316

High

863911

CRBB1
Beta-crystallin B1

2

0

High-throughput

0.316

High

1014023

T10IP
Testis-specific protein 10-interacting protein

2

0

High-throughput

0.316

High

1014073

FND11
Fibronectin type III domain-containing protein 11

2

0

High-throughput

0.316

High

1014090

TB22B
TBC1 domain family member 22B

2

0

High-throughput

0.316

High

452751

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1014045

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

0

High-throughput

0.279

Low

1014051

SIGL1
SIGLEC family-like protein 1

1

0

High-throughput

0.279

Low

1014072

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

1014085

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

1

0

High-throughput

0.279

Low

1014083

MYG1
MYG1 exonuclease

1

0

High-throughput

0.268

Low

486519

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

1014012

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1014081

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024