Protein: SPT46
Spermatogenesis-associated protein 46

Gene: SPT46, SPATA46
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q5T0L3

Gene Ontology (top 5):
GO:0007283 - spermatogenesis
GO:0007342 - fusion of sperm to egg plasma membrane involved in single fertilization
GO:0009566 - fertilization
GO:0030154 - cell differentiation
GO:0031965 - nuclear membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

876887

KC1A
Casein kinase I isoform alpha

3

2

High-throughput

0.609

High

1211639

SNX24
Sorting nexin-24

3

2

High-throughput

0.609

High

1154523

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.518

High

1211631

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

1211627

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

1

High-throughput

0.489

High

1211634

SNX22
Sorting nexin-22

1

1

High-throughput

0.489

High

897540

BPL1
Biotin--protein ligase

5

0

High-throughput

0.374

High

60818

TYW5
tRNA wybutosine-synthesizing protein 5

3

0

High-throughput

0.347

High

179724

MDM4
Protein Mdm4

3

0

High-throughput

0.347

High

1135428

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

3

0

High-throughput

0.347

High

1211635

MGLL
Monoglyceride lipase

3

0

High-throughput

0.347

High

1211633

CEP95
Centrosomal protein of 95 kDa

2

0

High-throughput

0.318

High

70251

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

225022

TLX3
T-cell leukemia homeobox protein 3

2

0

High-throughput

0.316

High

300376

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.316

High

1093842

TRAF1
TNF receptor-associated factor 1

2

0

High-throughput

0.316

High

1211632

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.299

High

261417

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

0

High-throughput

0.279

Low

413981

P53
Cellular tumor antigen p53

1

0

High-throughput

0.279

Low

833637

NAA10
N-alpha-acetyltransferase 10

1

0

High-throughput

0.279

Low

902198

RAB13
Ras-related protein Rab-13

1

0

High-throughput

0.279

Low

1058853

ZO1
Tight junction protein 1

1

0

High-throughput

0.279

Low

1211628

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.279

Low

1211630

OGFD1
Prolyl 3-hydroxylase OGFOD1

1

0

High-throughput

0.279

Low

1211637

PYRG2
CTP synthase 2

1

0

High-throughput

0.279

Low

1211638

NISCH
Nischarin

1

0

High-throughput

0.279

Low

384437

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.268

Low

729069

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

0

High-throughput

0.268

Low

1123929

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.268

Low

1211629

Q86V38
Atrophin 1

1

0

High-throughput

0.268

Low

1211636

ENKD1
Enkurin domain-containing protein 1

1

0

High-throughput

0.268

Low

422282

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025