Protein: THEM5
Acyl-coenzyme A thioesterase THEM5 (Acyl-CoA thioesterase THEM5) (EC 3.1.2.2) (Acyl-coenzyme A thioesterase 15) (Thioesterase superfamily member 5)

Gene: THEM5
Organism: Homo sapiens
Interactions: 21
UniProt ID: Q8N1Q8

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006631 - fatty acid metabolic process
GO:0035336 - long-chain fatty-acyl-CoA metabolic process
GO:0035965 - cardiolipin acyl-chain remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1211836

THEM4
Acyl-coenzyme A thioesterase THEM4

2

0

High-throughput

0.736

High

1323711

ALAT2
Alanine aminotransferase 2

2

1

High-throughput

0.601

High

944400

SYJ2B
Synaptojanin-2-binding protein

2

0

High-throughput

0.580

High

177568

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

1

High-throughput

0.536

High

61961

GTPBA
GTP-binding protein 10

1

0

High-throughput

0.513

High

275060

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.513

High

884672

SYHM
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

941685

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

0

High-throughput

0.513

High

1012073

KGD4
Alpha-ketoglutarate dehydrogenase component 4

1

0

High-throughput

0.513

High

1061342

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

0

High-throughput

0.513

High

1323714

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.513

High

1323716

ISCU
Iron-sulfur cluster assembly enzyme ISCU

1

0

High-throughput

0.513

High

1083666

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.445

High

405310

OAT
Ornithine aminotransferase, mitochondrial

1

0

High-throughput

0.426

High

1323712

RCC1L
RCC1-like G exchanging factor-like protein

1

0

High-throughput

0.426

High

1323717

NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

1

0

High-throughput

0.426

High

1323715

ZY11B
Protein zyg-11 homolog B

2

0

High-throughput

0.313

High

848898

MAGAB
Melanoma-associated antigen 11

1

0

High-throughput

0.299

High

1128778

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.279

Low

1323713

KLH15
Kelch-like protein 15

1

0

High-throughput

0.279

Low

1323718

CHSP1
Calcium-regulated heat-stable protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025