Protein: VPS28
Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)

Gene: VPS28
Organism: Homo sapiens
Interactions: 111
UniProt ID: Q9UK41

Gene Ontology (top 5):
GO:0000813 - ESCRT I complex
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1306614

TS101
Tumor susceptibility gene 101 protein

18

9

Small-scale

0.989

High

1334304

VP37B
Vacuolar protein sorting-associated protein 37B

9

8

Small-scale

0.974

High

1243806

VP37A
Vacuolar protein sorting-associated protein 37A

7

8

Small-scale

0.969

High

1204892

VP37D
Vacuolar protein sorting-associated protein 37D

2

8

High-throughput

0.811

High

60657

VP37C
Vacuolar protein sorting-associated protein 37C

2

8

Small-scale

0.768

High

1348811

UBAP1
Ubiquitin-associated protein 1

8

0

Small-scale

0.717

High

1290590

MB12A
Multivesicular body subunit 12A

4

3

High-throughput

0.699

High

476543

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

1

Small-scale

0.670

High

1084932

SMN
Survival motor neuron protein

3

1

High-throughput

0.668

High

1333190

MB12B
Multivesicular body subunit 12B

3

3

High-throughput

0.667

High

521403

SKIL
Ski-like protein

3

1

High-throughput

0.660

High

1230742

VPS52
Vacuolar protein sorting-associated protein 52 homolog

3

1

High-throughput

0.660

High

1309994

VPS25
Vacuolar protein-sorting-associated protein 25

3

1

Small-scale

0.656

High

1236738

USBP1
Harmonin-binding protein USHBP1

2

1

High-throughput

0.646

High

246403

SCN2B
Sodium channel subunit beta-2

3

0

High-throughput

0.638

High

1123685

DCAF6
DDB1- and CUL4-associated factor 6

3

0

High-throughput

0.638

High

1173411

STXB4
Syntaxin-binding protein 4

3

0

High-throughput

0.638

High

1292797

AB17A
Alpha/beta hydrolase domain-containing protein 17A

3

0

High-throughput

0.638

High

1305514

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

3

0

High-throughput

0.638

High

1311794

HAUS8
HAUS augmin-like complex subunit 8

3

0

High-throughput

0.638

High

1356286

AKA11
A-kinase anchor protein 11

3

0

High-throughput

0.638

High

1329073

CARD9
Caspase recruitment domain-containing protein 9

2

1

High-throughput

0.625

High

537126

TRI27
Zinc finger protein RFP

2

1

High-throughput

0.613

High

1262940

RASF5
Ras association domain-containing protein 5

2

1

High-throughput

0.613

High

1303329

HTF4
Transcription factor 12

2

3

High-throughput

0.613

High

1329405

GO45
Golgin-45

2

1

High-throughput

0.613

High

1345372

MBIP1
MAP3K12-binding inhibitory protein 1

2

1

High-throughput

0.613

High

1251488

LMO3
LIM domain only protein 3

2

1

High-throughput

0.606

High

1266460

SHC3
SHC-transforming protein 3

2

1

High-throughput

0.606

High

1348426

ABI2
Abl interactor 2

2

1

High-throughput

0.606

High

924936

GRB2
Growth factor receptor-bound protein 2

2

0

High-throughput

0.602

High

1188074

SETX
Probable helicase senataxin

2

0

High-throughput

0.602

High

792073

HD
Huntingtin

2

0

High-throughput

0.594

High

1234615

ARRD1
Arrestin domain-containing protein 1

2

0

High-throughput

0.585

High

212544

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.580

High

271215

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

0

High-throughput

0.580

High

871501

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

0

High-throughput

0.580

High

874354

GEM
GTP-binding protein GEM

2

0

High-throughput

0.580

High

989731

CDK18
Cyclin-dependent kinase 18

2

0

High-throughput

0.580

High

1223057

CC146
Coiled-coil domain-containing protein 146

2

0

High-throughput

0.580

High

1304880

TSNAX
Translin-associated protein X

2

0

High-throughput

0.580

High

1315984

BEX2
Protein BEX2

2

0

High-throughput

0.580

High

1354350

NXF1
Nuclear RNA export factor 1

2

0

High-throughput

0.580

High

1120347

CEP55
Centrosomal protein of 55 kDa

2

0

Small-scale

0.576

High

1201834

VPS36
Vacuolar protein-sorting-associated protein 36

2

4

Small-scale

0.571

High

995292

GOGA2
Golgin subfamily A member 2

2

1

High-throughput

0.559

High

1223788

SAXO1
Stabilizer of axonemal microtubules 1

2

1

High-throughput

0.559

High

1333730

AKTIP
AKT-interacting protein

1

0

Small-scale

0.529

High

529887

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

363341

FINC
Fibronectin

1

0

High-throughput

0.513

High

591142

BTF3
Transcription factor BTF3

1

0

High-throughput

0.513

High

598790

S1PR1
Sphingosine 1-phosphate receptor 1

1

0

High-throughput

0.513

High

847956

CP2J2
Cytochrome P450 2J2

1

0

High-throughput

0.513

High

975205

ACY1
Aminoacylase-1

1

0

High-throughput

0.513

High

1064246

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.513

High

1218469

WDFY1
WD repeat and FYVE domain-containing protein 1

1

0

High-throughput

0.513

High

1245348

KNL1
Kinetochore scaffold 1

1

0

High-throughput

0.513

High

1316973

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.513

High

1343768

ANLN
Anillin

1

0

High-throughput

0.513

High

1356289

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.513

High

1223832

CE57L
Centrosomal protein CEP57L1

1

0

High-throughput

0.486

High

800553

CBX5
Chromobox protein homolog 5

1

1

High-throughput

0.481

High

1012383

INCA1
Protein INCA1

1

1

High-throughput

0.481

High

1317483

TRI54
Tripartite motif-containing protein 54

1

3

High-throughput

0.481

High

1049178

TRI14
Tripartite motif-containing protein 14

1

2

High-throughput

0.479

High

1293006

SNF8
Vacuolar-sorting protein SNF8

1

2

Small-scale

0.479

High

127069

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

163442

XPO1
Exportin-1

1

0

High-throughput

0.458

High

348189

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

353018

IL1B
Interleukin-1 beta

1

0

Small-scale

0.458

High

504927

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

506674

BCR
Breakpoint cluster region protein

1

0

Small-scale

0.458

High

780294

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

847924

BRCA2
Breast cancer type 2 susceptibility protein

1

0

High-throughput

0.458

High

1043292

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1189526

ZFY16
Zinc finger FYVE domain-containing protein 16

1

0

Small-scale

0.458

High

1237515

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1239423

MLKL
Mixed lineage kinase domain-like protein

1

0

Small-scale

0.458

High

1245223

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1331585

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1331875

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

Small-scale

0.458

High

1355399

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

1356290

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

1

0

High-throughput

0.458

High

112120

M0QZK6
Multivesicular body subunit 12A

1

2

High-throughput

0.445

High

1356288

CD2AP
CD2-associated protein

1

2

Small-scale

0.445

High

551312

ITF2
Transcription factor 4

1

3

High-throughput

0.439

High

1299843

PNMA5
Paraneoplastic antigen-like protein 5

1

1

High-throughput

0.439

High

306348

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

0

High-throughput

0.438

High

402699

FABPH
Fatty acid-binding protein, heart

1

0

High-throughput

0.438

High

517532

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

240246

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

497763

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1044252

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.426

High

1344050

PDLI7
PDZ and LIM domain protein 7

1

0

High-throughput

0.426

High

1138929

UBE2U
Ubiquitin-conjugating enzyme E2 U

3

0

High-throughput

0.347

High

1235173

S2541
Mitochondrial carrier protein SCaMC-3L

3

0

High-throughput

0.347

High

1317950

EVG1
UPF0193 protein EVG1

3

0

High-throughput

0.342

High

1217389

PCP2
Purkinje cell protein 2 homolog

2

0

High-throughput

0.328

High

495770

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

2

0

High-throughput

0.316

High

849827

SUOX
Sulfite oxidase, mitochondrial

2

0

High-throughput

0.316

High

1333243

NRDE2
Nuclear exosome regulator NRDE2

2

0

High-throughput

0.316

High

1349227

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

2

0

High-throughput

0.313

High

300283

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.279

Low

1047469

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.279

Low

1189582

UBE3B
Ubiquitin-protein ligase E3B

1

0

High-throughput

0.279

Low

1202577

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1205397

STX12
Syntaxin-12

1

0

High-throughput

0.279

Low

1223426

ZDH23
Palmitoyltransferase ZDHHC23

1

0

High-throughput

0.279

Low

1291825

CERS2
Ceramide synthase 2

1

0

High-throughput

0.279

Low

1297600

F227B
Protein FAM227B

1

0

High-throughput

0.279

Low

1356287

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024