Protein: TTYH2
Protein tweety homolog 2 (hTTY2) (Volume-regulated anion channel subunit TTYH2)

Gene: TTYH2
Organism: Homo sapiens
Interactions: 26
UniProt ID: Q9BSA4

Gene Ontology (top 5):
GO:0005229 - intracellularly calcium-gated chloride channel activity
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0015813 - L-glutamate transmembrane transport
GO:0034707 - chloride channel complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1412222

TTYH2
Protein tweety homolog 2

2

2

Small-scale

0.754

High

861751

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

2

Small-scale

0.578

High

921763

COPB
Coatomer subunit beta

1

0

Small-scale

0.573

High

186934

GPR37
Prosaposin receptor GPR37

1

3

High-throughput

0.541

High

638237

S1PR1
Sphingosine 1-phosphate receptor 1

1

11

High-throughput

0.536

High

640456

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

5

High-throughput

0.536

High

987909

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.536

High

1412224

PILRB
Paired immunoglobulin-like type 2 receptor beta

1

1

High-throughput

0.536

High

411026

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

High-throughput

0.501

High

593483

PGFRA
Platelet-derived growth factor receptor alpha

1

1

High-throughput

0.501

High

1312122

TARG1
Trafficking regulator of GLUT4 1

1

2

High-throughput

0.481

High

465627

IGF1R
Insulin-like growth factor 1 receptor

1

0

High-throughput

0.480

High

648646

FGFR4
Fibroblast growth factor receptor 4

1

0

High-throughput

0.480

High

767320

MERL
Merlin

1

0

High-throughput

0.480

High

1099659

GRM1
Metabotropic glutamate receptor 1

1

0

High-throughput

0.480

High

63694

A5PKU2
TUSC5 protein

1

2

High-throughput

0.470

High

136970

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.458

High

842928

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

1

High-throughput

0.457

High

106567

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

1412223

MANS1
MANSC domain-containing protein 1

2

0

High-throughput

0.328

High

1412225

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.292

High

1238253

CK087
Uncharacterized protein C11orf87

1

0

High-throughput

0.279

Low

718840

CCND2
G1/S-specific cyclin-D2

1

0

High-throughput

0.261

Low

755510

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.261

Low

1369157

KAT2A
Histone acetyltransferase KAT2A

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025