Protein: SYNE4
Nesprin-4 (KASH domain-containing protein 4) (KASH4) (Nuclear envelope spectrin repeat protein 4)

Gene: SYNE4
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q8N205

Gene Ontology (top 5):
GO:0005640 - nuclear outer membrane
GO:0034993 - meiotic nuclear membrane microtubule tethering complex
GO:0045198 - establishment of epithelial cell apical/basal polarity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1231175

SUN2
SUN domain-containing protein 2

2

1

Small-scale

0.819

High

299688

SUN1
SUN domain-containing protein 1

1

1

Small-scale

0.716

High

1231142

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

5

1

High-throughput

0.660

High

1231167

KLC4
Kinesin light chain 4

4

8

High-throughput

0.644

High

1079672

ADIPO
Adiponectin

4

1

High-throughput

0.639

High

229878

KIF5C
Kinesin heavy chain isoform 5C

3

2

High-throughput

0.609

High

233076

FZD6
Frizzled-6

3

2

High-throughput

0.609

High

702945

KINH
Kinesin-1 heavy chain

3

2

High-throughput

0.609

High

992365

KLC1
Kinesin light chain 1

3

8

High-throughput

0.609

High

1017542

KIF5A
Kinesin heavy chain isoform 5A

3

2

High-throughput

0.609

High

1081860

EXT1
Exostosin-1

3

1

High-throughput

0.609

High

1159981

KLC3
Kinesin light chain 3

3

7

High-throughput

0.609

High

1231158

KLC2
Kinesin light chain 2

3

8

High-throughput

0.609

High

1231162

FZD3
Frizzled-3

3

2

High-throughput

0.609

High

1231181

MAN1
Inner nuclear membrane protein Man1

3

1

High-throughput

0.609

High

1049263

KEAP1
Kelch-like ECH-associated protein 1

2

1

High-throughput

0.558

High

1053378

FZD2
Frizzled-2

2

2

High-throughput

0.558

High

1133843

ZN648
Zinc finger protein 648

2

1

High-throughput

0.553

High

1231141

CLD19
Claudin-19

2

2

High-throughput

0.553

High

315138

CLD7
Claudin-7

1

2

High-throughput

0.523

High

881975

CLD8
Claudin-8

1

2

High-throughput

0.523

High

1120785

KLH12
Kelch-like protein 12

1

1

High-throughput

0.523

High

1231152

KLRG1
Killer cell lectin-like receptor subfamily G member 1

1

1

High-throughput

0.523

High

66548

A8K660
Adiponectin

1

1

High-throughput

0.470

High

217186

EXTL3
Exostosin-like 3

1

1

High-throughput

0.437

High

1231143

LEMD2
LEM domain-containing protein 2

1

1

High-throughput

0.437

High

1168577

SYNE3
Nesprin-3

1

0

Small-scale

0.426

High

3346

A0A0S2Z5K4
Hexosyltransferase

1

1

High-throughput

0.417

High

1084093

OCLN
Occludin

4

0

High-throughput

0.368

High

1022732

MALL
MAL-like protein

3

0

High-throughput

0.352

High

1231155

CEP19
Centrosomal protein of 19 kDa

3

0

High-throughput

0.352

High

1231164

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

3

0

High-throughput

0.352

High

129402

GOLI4
Golgi integral membrane protein 4

3

0

High-throughput

0.347

High

200749

ADCY6
Adenylate cyclase type 6

3

0

High-throughput

0.347

High

213230

SNG2
Synaptogyrin-2

3

0

High-throughput

0.347

High

276377

AP1G2
AP-1 complex subunit gamma-like 2

3

0

High-throughput

0.347

High

305540

ZFPL1
Zinc finger protein-like 1

3

0

High-throughput

0.347

High

311584

SMC2
Structural maintenance of chromosomes protein 2

3

0

High-throughput

0.347

High

789308

CNDD3
Condensin-2 complex subunit D3

3

0

High-throughput

0.347

High

1035086

TUSC3
Tumor suppressor candidate 3

3

0

High-throughput

0.347

High

1152354

CNDH2
Condensin-2 complex subunit H2

3

0

High-throughput

0.347

High

1203958

LSR
Lipolysis-stimulated lipoprotein receptor

3

0

High-throughput

0.347

High

1231148

SARAF
Store-operated calcium entry-associated regulatory factor

3

0

High-throughput

0.347

High

1231154

B3GT6
Beta-1,3-galactosyltransferase 6

3

0

High-throughput

0.347

High

1231159

TM231
Transmembrane protein 231

3

0

High-throughput

0.347

High

1231160

FKRP
Ribitol 5-phosphate transferase FKRP

3

0

High-throughput

0.347

High

1231163

GPC5C
G-protein coupled receptor family C group 5 member C

3

0

High-throughput

0.347

High

1231178

DSE
Dermatan-sulfate epimerase

3

0

High-throughput

0.347

High

1231182

ZDHC9
Palmitoyltransferase ZDHHC9

3

0

High-throughput

0.347

High

514422

PSPC
Surfactant protein C

2

0

High-throughput

0.343

High

1231157

CLC7A
C-type lectin domain family 7 member A

2

0

High-throughput

0.334

High

1231166

SERC1
Serine incorporator 1

2

0

High-throughput

0.328

High

1231174

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

0

High-throughput

0.327

High

1231145

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.318

High

623647

IBP5
Insulin-like growth factor-binding protein 5

2

0

High-throughput

0.316

High

1075129

TCEA2
Transcription elongation factor A protein 2

2

0

High-throughput

0.316

High

1221920

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

0

High-throughput

0.316

High

134995

SARCO
Sarcolipin

1

0

High-throughput

0.299

High

260264

ENTP3
Ectonucleoside triphosphate diphosphohydrolase 3

1

0

High-throughput

0.299

High

326126

TSN15
Tetraspanin-15

1

0

High-throughput

0.299

High

549196

ZN250
Zinc finger protein 250

1

0

High-throughput

0.299

High

873250

EMP1
Epithelial membrane protein 1

1

0

High-throughput

0.299

High

882075

EP3B
Epididymal secretory protein E3-beta

1

0

High-throughput

0.299

High

991069

CXCL9
C-X-C motif chemokine 9

1

0

High-throughput

0.299

High

996246

CD47
Leukocyte surface antigen CD47

1

0

High-throughput

0.299

High

1019258

TM115
Transmembrane protein 115

1

0

High-throughput

0.299

High

1074055

SC23B
Protein transport protein Sec23B

1

0

High-throughput

0.299

High

1125051

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.299

High

1126622

DB121
Beta-defensin 121

1

0

High-throughput

0.299

High

1135758

RIPP2
Protein ripply2

1

0

High-throughput

0.299

High

1162817

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.299

High

1166153

OLFM4
Olfactomedin-4

1

0

High-throughput

0.299

High

1169541

TM182
Transmembrane protein 182

1

0

High-throughput

0.299

High

1199821

KTN1
Kinectin

1

0

High-throughput

0.299

High

1203433

TRI69
E3 ubiquitin-protein ligase TRIM69

1

0

High-throughput

0.299

High

1231147

FATE1
Fetal and adult testis-expressed transcript protein

1

0

High-throughput

0.299

High

1231150

F241B
Protein FAM241B

1

0

High-throughput

0.299

High

1231151

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.299

High

1231153

SC22A
Vesicle-trafficking protein SEC22a

1

0

High-throughput

0.299

High

1231156

TM147
BOS complex subunit TMEM147

1

0

High-throughput

0.299

High

1231161

SENP2
Sentrin-specific protease 2

1

0

High-throughput

0.299

High

1231165

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.299

High

1231168

TM140
Transmembrane protein 140

1

0

High-throughput

0.299

High

1231171

TM248
Transmembrane protein 248

1

0

High-throughput

0.299

High

1231172

PAQR5
Membrane progestin receptor gamma

1

0

High-throughput

0.299

High

1231173

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

0

High-throughput

0.299

High

1231179

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.299

High

1231180

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.299

High

529398

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.282

High

1231146

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.279

Low

1231144

Q8TBU1
Oligosaccharyltransferase complex subunit

1

0

High-throughput

0.268

Low

1231149

OPTN
Optineurin

1

0

High-throughput

0.268

Low

622962

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.265

Low

835878

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.265

Low

931728

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.265

Low

1231176

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.265

Low

1231177

KS6A6
Ribosomal protein S6 kinase alpha-6

1

0

High-throughput

0.265

Low

253792

XYLK
Glycosaminoglycan xylosylkinase

1

0

High-throughput

0.249

Low

310715

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

0

High-throughput

0.249

Low

1173493

TMTC3
Protein O-mannosyl-transferase TMTC3

1

0

High-throughput

0.249

Low

1222667

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low

1231169

TM39A
Transmembrane protein 39A

1

0

High-throughput

0.249

Low

1231170

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.249

Low

1231183

POMT1
Protein O-mannosyl-transferase 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024