Protein: DRB5
HLA class II histocompatibility antigen, DR beta 5 chain (DR beta-5) (DR2-beta-2) (Dw2) (MHC class II antigen DRB5)

Gene: DRB5, HLA-DRB5
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q30154

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0002250 - adaptive immune response
GO:0002503 - peptide antigen assembly with MHC class II protein complex
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

380295

DRA
HLA class II histocompatibility antigen, DR alpha chain

3

18

High-throughput

0.861

High

380436

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

19

High-throughput

0.691

High

520866

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

19

High-throughput

0.691

High

1022397

IDD
Integral membrane protein DGCR2/IDD

1

10

High-throughput

0.618

High

409405

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

19

High-throughput

0.618

High

380548

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

20

High-throughput

0.575

High

1180909

UBR3
E3 ubiquitin-protein ligase UBR3

2

2

High-throughput

0.574

High

535129

BIP
Endoplasmic reticulum chaperone BiP

1

11

High-throughput

0.536

High

565627

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

14

High-throughput

0.536

High

1180910

TBA1A
Tubulin alpha-1A chain

1

8

High-throughput

0.536

High

1180911

ABD12
Lysophosphatidylserine lipase ABHD12

1

3

High-throughput

0.536

High

1180913

EMC5
ER membrane protein complex subunit 5

1

3

High-throughput

0.536

High

1180915

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

0

High-throughput

0.513

High

76117

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

5

High-throughput

0.489

High

1136220

EMC2
ER membrane protein complex subunit 2

1

4

High-throughput

0.489

High

420803

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

8

Small-scale

0.479

High

461543

HS90A
Heat shock protein HSP 90-alpha

1

10

Small-scale

0.479

High

468436

HS90B
Heat shock protein HSP 90-beta

1

10

Small-scale

0.479

High

537257

HSP7C
Heat shock cognate 71 kDa protein

1

7

Small-scale

0.479

High

549443

CD20
B-lymphocyte antigen CD20

1

3

Small-scale

0.479

High

573122

KPYM
Pyruvate kinase PKM

1

3

Small-scale

0.479

High

899695

ANX11
Annexin A11

1

5

Small-scale

0.479

High

971583

1433E
14-3-3 protein epsilon

1

3

Small-scale

0.479

High

838111

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

High-throughput

0.437

High

1180916

DS13B
Dual specificity protein phosphatase 13B

1

1

High-throughput

0.437

High

163115

CHK1
Serine/threonine-protein kinase Chk1

3

0

High-throughput

0.345

High

899937

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.282

High

1180912

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.279

Low

1180914

NJMU
Protein Njmu-R1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025