Protein: PRI1
DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49)

Gene: PRI1, PRIM1
Organism: Homo sapiens
Interactions: 79
UniProt ID: P49642

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005658 - alpha DNA polymerase:primase complex
GO:0006269 - DNA replication, synthesis of primer

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

885522

PRI2
DNA primase large subunit

6

3

Small-scale

0.948

High

885527

RAE1L
mRNA export factor RAE1

4

0

High-throughput

0.664

High

487986

DPOLA
DNA polymerase alpha catalytic subunit

3

4

Small-scale

0.662

High

885529

DPOA2
DNA polymerase alpha subunit B

2

3

High-throughput

0.628

High

885547

NLGNY
Neuroligin-4, Y-linked

2

1

High-throughput

0.611

High

885554

MMS19
MMS19 nucleotide excision repair protein homolog

3

0

Small-scale

0.606

High

885538

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.602

High

885552

RNF31
E3 ubiquitin-protein ligase RNF31

2

0

High-throughput

0.602

High

885560

STN1
CST complex subunit STN1

2

0

High-throughput

0.585

High

407599

S100B
Protein S100-B

2

0

High-throughput

0.576

High

241080

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

588191

RFA2
Replication protein A 32 kDa subunit

2

0

Small-scale

0.559

High

694914

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

Small-scale

0.559

High

767686

RFA3
Replication protein A 14 kDa subunit

2

0

Small-scale

0.559

High

885553

BT3L4
Transcription factor BTF3 homolog 4

2

1

High-throughput

0.549

High

885567

CIA2B
Cytosolic iron-sulfur assembly component 2B

2

0

Small-scale

0.547

High

549549

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.536

High

158415

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.513

High

630224

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.513

High

885528

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

885532

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.513

High

885534

DCA10
DDB1- and CUL4-associated factor 10

1

0

High-throughput

0.513

High

885536

KAD9
Adenylate kinase 9

1

0

High-throughput

0.513

High

885540

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.513

High

885549

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

885550

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

885557

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

885568

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

0

High-throughput

0.513

High

843377

HD
Huntingtin

1

0

High-throughput

0.493

High

629657

BTF3
Transcription factor BTF3

1

1

High-throughput

0.489

High

885543

KLH34
Kelch-like protein 34

1

1

High-throughput

0.489

High

185522

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

881488

CDK8
Cyclin-dependent kinase 8

1

1

High-throughput

0.479

High

885530

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.460

High

259620

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

315281

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

345524

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

362971

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

385554

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

559264

XRCC5
X-ray repair cross-complementing protein 5

1

0

Small-scale

0.458

High

785011

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

885523

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

885525

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

885526

H31
Histone H3.1

1

0

High-throughput

0.458

High

885539

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

885541

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

885545

NIN
Ninein

1

0

High-throughput

0.458

High

885561

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

885563

ANLN
Anillin

1

0

High-throughput

0.458

High

885524

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.445

High

391203

FRIL
Ferritin light chain

1

0

High-throughput

0.426

High

437645

HEPS
Serine protease hepsin

1

0

High-throughput

0.426

High

765249

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

66980

A6NMU8
Neuroligin 4 Y-linked

1

1

High-throughput

0.407

High

885548

LIPH
Lipase member H

3

0

High-throughput

0.347

High

885566

KLH20
Kelch-like protein 20

2

0

High-throughput

0.318

High

885564

PNMA2
Paraneoplastic antigen Ma2

2

0

High-throughput

0.313

High

74451

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.279

Low

190329

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

334157

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.279

Low

848599

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.279

Low

873876

KCNJ5
G protein-activated inward rectifier potassium channel 4

1

0

High-throughput

0.279

Low

885535

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.279

Low

885542

MILR1
Allergin-1

1

0

High-throughput

0.279

Low

885555

MDFI
MyoD family inhibitor

1

0

High-throughput

0.279

Low

885556

DUS9
Dual specificity protein phosphatase 9

1

0

High-throughput

0.279

Low

885558

DNAI2
Dynein axonemal intermediate chain 2

1

0

High-throughput

0.279

Low

885562

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

885565

NTNG1
Netrin-G1

1

0

High-throughput

0.279

Low

302782

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.249

Low

885546

FBXL6
F-box/LRR-repeat protein 6

1

0

Small-scale

0.249

Low

885559

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

885551

RM38
Large ribosomal subunit protein mL38

1

0

High-throughput

0.238

Low

58795

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low

664847

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.232

Low

885531

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

0

High-throughput

0.232

Low

885533

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

1

0

High-throughput

0.232

Low

885537

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

885544

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025