Protein: SLN12
Ribonuclease SLFN12 (EC 3.1.-.-) (Schlafen family member 12)

Gene: SLN12, SLFN12
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q8IYM2

Gene Ontology (top 5):
GO:0004540 - RNA nuclease activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0016075 - rRNA catabolic process
GO:0043022 - ribosome binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1315289

PDLI7
PDZ and LIM domain protein 7

2

0

High-throughput

0.602

High

1315286

TRI63
E3 ubiquitin-protein ligase TRIM63

1

1

High-throughput

0.541

High

1315288

TRI55
Tripartite motif-containing protein 55

1

2

High-throughput

0.541

High

385946

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

High-throughput

0.515

High

216484

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

2

High-throughput

0.508

High

1239622

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

3

High-throughput

0.508

High

822749

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.493

High

929809

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

981580

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.493

High

1279624

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

1315287

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

0

High-throughput

0.493

High

280714

PR40A
Pre-mRNA-processing factor 40 homolog A

1

2

High-throughput

0.470

High

398005

KLKB1
Plasma kallikrein

1

1

High-throughput

0.470

High

562203

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.470

High

897335

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

591326

CD44
CD44 antigen

1

0

High-throughput

0.426

High

616773

SDC1
Syndecan-1

1

1

High-throughput

0.407

High

760473

SDC2
Syndecan-2

1

1

High-throughput

0.407

High

184871

SPTC1
Serine palmitoyltransferase 1

1

0

High-throughput

0.268

Low

369550

ANGT
Angiotensinogen

1

0

High-throughput

0.268

Low

441554

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

449528

LIPL
Lipoprotein lipase

1

0

High-throughput

0.268

Low

1292902

Q86WV8
TSC complex subunit 1

1

0

High-throughput

0.268

Low

829454

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

935913

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

1315284

CAMKV
CaM kinase-like vesicle-associated protein

1

0

High-throughput

0.232

Low

1315285

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025