Protein: KRAF1
Raf homolog serine/threonine-protein kinase Raf (D-Raf) (dRAF-1) (EC 2.7.11.1) (Protein pole-hole)

Gene: KRAF1, Raf
Organism: Drosophila melanogaster
Interactions: 98
UniProt ID: P11346

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0002168 - instar larval development
GO:0004674 - protein serine/threonine kinase activity
GO:0004709 - MAP kinase kinase kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

442988

RAS1
Ras-like protein 1

5

20

Small-scale

0.909

High

507714

DSOR1
Dual specificity mitogen-activated protein kinase kinase dSOR1

5

20

Small-scale

0.897

High

442951

RAP1
Ras-related protein Rap1

3

20

Small-scale

0.849

High

507724

Q7KNQ9
Connector enhancer of KSR protein CNK

3

19

Small-scale

0.839

High

507712

Q24171
AT08303p

2

20

Small-scale

0.767

High

381631

RAS2
Ras-like protein 2

2

20

Small-scale

0.754

High

337671

SRC64
Tyrosine-protein kinase Src64B

1

19

Small-scale

0.724

High

507701

1433Z
14-3-3 protein zeta

2

20

High-throughput

0.713

High

332189

O96692
RE63021p

1

20

High-throughput

0.698

High

437049

CSK2A
Casein kinase II subunit alpha

1

20

Small-scale

0.647

High

507694

KRAF1
Raf homolog serine/threonine-protein kinase Raf

1

20

Small-scale

0.618

High

507702

ERKA
Mitogen-activated protein kinase ERK-A

1

20

High-throughput

0.618

High

507708

1433E
14-3-3 protein epsilon

1

15

High-throughput

0.618

High

507710

GRAP
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

507721

Q7KM03
Ecdysone-induced protein 63E, isoform G

1

17

High-throughput

0.618

High

507730

Q8MLP1
Sterile20-like kinase, isoform A

1

20

Small-scale

0.618

High

507741

Q9VAH7
N-terminal kinase-like protein

1

12

High-throughput

0.618

High

507745

Q9VEN3
non-specific serine/threonine protein kinase

1

20

Small-scale

0.618

High

507746

Q9VGI4
LD17393p

1

17

High-throughput

0.618

High

507767

Q9W179
Sterile20-like kinase, isoform B

1

20

Small-scale

0.618

High

365432

HSP83
Heat shock protein 83

2

20

High-throughput

0.552

High

507738

Q9V393
Kurtz arrestin

1

6

Small-scale

0.515

High

507699

TORSO
Tyrosine-protein kinase receptor torso

1

20

High-throughput

0.492

High

507711

Q24170
KSR

1

20

High-throughput

0.492

High

507715

JAK
Tyrosine-protein kinase hopscotch

1

20

High-throughput

0.492

High

115666

M9PFW8
Apollo, isoform B

1

2

High-throughput

0.479

High

137736

CH60A
Heat shock protein 60A

1

10

High-throughput

0.479

High

186185

GBLP
Small ribosomal subunit protein RACK1

1

11

High-throughput

0.479

High

248430

KPYK
Pyruvate kinase

1

3

High-throughput

0.479

High

361134

ACT2
Actin-42A

1

4

High-throughput

0.479

High

365383

HSP71
Major heat shock 70 kDa protein Ab

1

11

High-throughput

0.479

High

445193

TBB3
Tubulin beta-3 chain

1

10

High-throughput

0.479

High

507695

TCPA
T-complex protein 1 subunit alpha

1

15

High-throughput

0.479

High

507697

EF2
Eukaryotic translation elongation factor 2

1

5

High-throughput

0.479

High

507698

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

7

High-throughput

0.479

High

507700

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

6

High-throughput

0.479

High

507704

RS18
Small ribosomal subunit protein uS13

1

1

High-throughput

0.479

High

507707

RB87F
Heterogeneous nuclear ribonucleoprotein 87F

1

20

High-throughput

0.479

High

507709

IF4A
Eukaryotic initiation factor 4A

1

4

High-throughput

0.479

High

507713

CDC37
Hsp90 co-chaperone Cdc37

1

9

High-throughput

0.479

High

507717

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

17

High-throughput

0.479

High

507722

Q7KMQ0
26S proteasome regulatory subunit 7

1

1

High-throughput

0.479

High

507725

GGYF1
GIGYF family protein Gyf

1

20

High-throughput

0.479

High

507729

Q8IRH0
LP21249p

1

2

High-throughput

0.479

High

507732

Q8MST5
Tubulin beta chain

1

10

High-throughput

0.479

High

507733

Q8T8W3
AT21416p

1

3

High-throughput

0.479

High

507737

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

4

High-throughput

0.479

High

507739

Q9V3V6
26S proteasome regulatory complex subunit p50

1

4

High-throughput

0.479

High

507742

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

2

High-throughput

0.479

High

507747

IPO9
Importin-9

1

8

High-throughput

0.479

High

507748

Q9VHN7
transketolase

1

3

High-throughput

0.479

High

507751

Q9VJH2
Aspartyl-tRNA synthetase, mitochondrial, isoform A

1

4

High-throughput

0.479

High

507752

NFS1
Cysteine desulfurase, mitochondrial

1

3

High-throughput

0.479

High

507754

Q9VLC5
Aldehyde dehydrogenase

1

2

High-throughput

0.479

High

507759

DJSHV
DnaJ homolog shv

1

11

High-throughput

0.479

High

507761

Q9VRL8
Blanks

1

9

High-throughput

0.479

High

507762

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

507764

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.479

High

507770

DDB1
DNA damage-binding protein 1

1

2

High-throughput

0.479

High

115218

M9PEH8
Fiery mountain, isoform D

1

0

High-throughput

0.458

High

507726

CSN8
COP9 signalosome complex subunit 8

1

0

High-throughput

0.458

High

507734

DYLT
Dynein light chain Tctex-type

1

0

High-throughput

0.458

High

507736

KCMF1
E3 ubiquitin-protein ligase Kcmf1

1

0

High-throughput

0.458

High

507749

NESD
Protein nessun dorma

1

0

High-throughput

0.458

High

184102

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.437

High

333080

O97365
BM-40

1

2

High-throughput

0.437

High

507705

COPB
Coatomer subunit beta

1

6

High-throughput

0.437

High

507706

RS15A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

507716

ADT
ADP,ATP carrier protein

1

7

High-throughput

0.437

High

507718

Q5KTT4
Eukaryotic translation initiation factor 4 gamma 2

1

4

High-throughput

0.437

High

507719

NUP50
Nuclear pore complex protein Nup50

1

1

High-throughput

0.437

High

507723

Q7KN94
Electron transfer flavoprotein subunit alpha

1

1

High-throughput

0.437

High

507728

Q7KVX1
Pyruvate dehydrogenase E1 component subunit alpha

1

3

High-throughput

0.437

High

507735

CATL
Cathepsin L

1

3

High-throughput

0.437

High

507740

Q9VA69
procollagen-proline 4-dioxygenase

1

4

High-throughput

0.437

High

507743

Q9VAY6
Pre-mRNA-splicing factor SPF27

1

1

High-throughput

0.437

High

507750

Q9VJD1
Glucosidase 2 subunit beta

1

1

High-throughput

0.437

High

507757

Q9VNA3
GH21273p

1

1

High-throughput

0.437

High

507763

GALL2
MIP18 family protein galla-2

1

2

High-throughput

0.437

High

507765

Q9VWQ3
LD35981p

1

3

High-throughput

0.437

High

507766

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.437

High

507768

Q9W1I0
TAR DNA-binding protein-43 homolog, isoform A

1

19

High-throughput

0.437

High

507769

RL17
Large ribosomal subunit protein uL22

1

2

High-throughput

0.437

High

507771

Q9Y165
BcDNA.GH02435

1

2

High-throughput

0.437

High

507760

Q9VQW4
IP21067p

1

0

High-throughput

0.265

Low

89934

D5SHV2
MIP21957p

1

0

High-throughput

0.249

Low

221095

O46307
EG:8D8.4 protein

1

0

High-throughput

0.249

Low

507696

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.249

Low

507703

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.249

Low

507720

ARC1
Activity-regulated cytoskeleton associated protein 1

1

0

High-throughput

0.249

Low

507727

Q7KTL4
Septin interacting protein 2, isoform C

1

0

High-throughput

0.249

Low

507731

Q8MRW1
SD19278p

1

0

High-throughput

0.249

Low

507744

Q9VBN5
60S ribosomal protein L27

1

0

High-throughput

0.249

Low

507753

Q9VL93
GEO07195p1

1

0

High-throughput

0.249

Low

507755

TCP4
RNA polymerase II transcriptional coactivator

1

0

High-throughput

0.249

Low

507756

Q9VN39
RE74585p

1

0

High-throughput

0.249

Low

507758

Q9VNB9
Large ribosomal subunit protein eL33

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024