Protein: CSF1
Macrophage colony-stimulating factor 1 (CSF-1) (MCSF) (Proteoglycan macrophage colony-stimulating factor) (PG-M-CSF) [Cleaved into: Processed macrophage colony-stimulating factor 1; Macrophage colony-stimulating factor 1 43 kDa subunit]

Gene: CSF1
Organism: Mus musculus
Interactions: 46
UniProt ID: P07141

Gene Ontology (top 5):
GO:0001780 - neutrophil homeostasis
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0002158 - osteoclast proliferation
GO:0002687 - positive regulation of leukocyte migration
GO:0002931 - response to ischemia

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

450377

CSF1R
Macrophage colony-stimulating factor 1 receptor

2

6

Small-scale

0.820

High

450376

CSF1
Macrophage colony-stimulating factor 1

1

5

Small-scale

0.716

High

431315

SRC
Proto-oncogene tyrosine-protein kinase Src

1

7

Small-scale

0.515

High

450398

CLD11
Claudin-11

1

0

Small-scale

0.513

High

450405

Q8C161
Protein AAR2 homolog

1

1

Small-scale

0.489

High

450413

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

Small-scale

0.489

High

450384

BCL6
B-cell lymphoma 6 protein homolog

1

4

Small-scale

0.479

High

450392

TF65
Transcription factor p65

1

3

Small-scale

0.479

High

204218

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

4

Small-scale

0.445

High

313322

ITM2B
Integral membrane protein 2B

1

3

Small-scale

0.445

High

450378

ANXA1
Annexin A1

1

3

Small-scale

0.445

High

450379

EF1A1
Elongation factor 1-alpha 1

1

2

Small-scale

0.445

High

450380

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

Small-scale

0.445

High

450383

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

4

Small-scale

0.445

High

450386

KSYK
Tyrosine-protein kinase SYK

1

15

Small-scale

0.445

High

450388

ACTB
Actin, cytoplasmic 1

1

1

Small-scale

0.445

High

450389

ROCK2
Rho-associated protein kinase 2

1

2

Small-scale

0.445

High

450390

RGS14
Regulator of G-protein signaling 14

1

1

Small-scale

0.445

High

450391

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

2

Small-scale

0.445

High

450393

MARK2
Serine/threonine-protein kinase MARK2

1

1

Small-scale

0.445

High

450396

MYO1G
Unconventional myosin-Ig

1

6

Small-scale

0.445

High

450401

JAK2
Tyrosine-protein kinase JAK2

1

12

Small-scale

0.445

High

450403

FLNB
Filamin-B

1

3

Small-scale

0.445

High

450407

MYH9
Myosin-9

1

2

Small-scale

0.445

High

450414

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

7

Small-scale

0.445

High

450415

KAD1
Adenylate kinase isoenzyme 1

1

1

Small-scale

0.445

High

450416

MYO1C
Unconventional myosin-Ic

1

6

Small-scale

0.445

High

450402

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

6

High-throughput

0.437

High

450382

MYD88
Myeloid differentiation primary response protein MyD88

1

0

Small-scale

0.426

High

450397

ICAM5
Intercellular adhesion molecule 5

1

0

Small-scale

0.426

High

312065

MYO1A
Unconventional myosin-Ia

1

9

Small-scale

0.407

High

450385

CAZA1
F-actin-capping protein subunit alpha-1

1

1

Small-scale

0.407

High

450387

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

2

Small-scale

0.407

High

450395

PP12C
Protein phosphatase 1 regulatory subunit 12C

1

3

Small-scale

0.407

High

450399

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

1

Small-scale

0.407

High

450400

MYH10
Myosin-10

1

2

Small-scale

0.407

High

450404

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

1

Small-scale

0.407

High

450406

MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2

1

2

Small-scale

0.407

High

450409

MYO5A
Unconventional myosin-Va

1

2

Small-scale

0.407

High

450410

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

1

Small-scale

0.407

High

450411

EF1G
Elongation factor 1-gamma

1

3

Small-scale

0.407

High

450412

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

2

Small-scale

0.407

High

450381

TPM3
Tropomyosin alpha-3 chain

1

0

Small-scale

0.232

Low

450394

CTR1
High affinity cationic amino acid transporter 1

1

0

Small-scale

0.232

Low

450408

CELR3
Cadherin EGF LAG seven-pass G-type receptor 3

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025