Protein: SYPL1
Synaptophysin-like protein 1 (Pantophysin)

Gene: SYPL1
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q16563

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission
GO:0016020 - membrane
GO:0030141 - secretory granule
GO:0030672 - synaptic vesicle membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

989335

VAMP2
Vesicle-associated membrane protein 2

3

6

High-throughput

0.675

High

1154624

VAMP3
Vesicle-associated membrane protein 3

3

6

High-throughput

0.675

High

1158782

VAMP8
Vesicle-associated membrane protein 8

2

6

High-throughput

0.628

High

140284

SDCB1
Syntenin-1

2

1

High-throughput

0.606

High

719438

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

2

1

High-throughput

0.606

High

609689

LEG3
Galectin-3

2

0

High-throughput

0.602

High

1158786

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

2

0

High-throughput

0.580

High

1158774

RBFA
Putative ribosome-binding factor A, mitochondrial

2

1

High-throughput

0.553

High

698697

CALX
Calnexin

1

0

High-throughput

0.513

High

1158784

TX101
Testis-expressed protein 101

1

0

High-throughput

0.513

High

508046

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

1158780

Q96AL5
PBX3 protein

1

3

High-throughput

0.470

High

404088

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

633921

ATP4A
Potassium-transporting ATPase alpha chain 1

1

0

Small-scale

0.458

High

1158772

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

834974

S19A1
Reduced folate transporter

1

1

High-throughput

0.445

High

1158778

MOT10
Monocarboxylate transporter 10

1

1

High-throughput

0.445

High

1158785

S19A3
Thiamine transporter 2

1

1

High-throughput

0.445

High

823943

PBX3
Pre-B-cell leukemia transcription factor 3

1

3

High-throughput

0.439

High

106008

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

1158771

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

841183

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

845660

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.426

High

1158770

ZNT10
Calcium/manganese antiporter SLC30A10

1

0

High-throughput

0.426

High

1158787

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.426

High

1158788

S17A5
Sialin

1

0

High-throughput

0.426

High

1158777

MFSD8
Major facilitator superfamily domain-containing protein 8

1

1

High-throughput

0.407

High

1158768

TEX44
Testis-expressed protein 44

2

0

High-throughput

0.316

High

1158781

CIB3
Calcium and integrin-binding family member 3

2

0

High-throughput

0.316

High

1158783

SYTM
Threonine--tRNA ligase, mitochondrial

2

0

High-throughput

0.316

High

1158773

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1158776

MCU
Calcium uniporter protein, mitochondrial

1

0

High-throughput

0.279

Low

1158779

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

0

Small-scale

0.276

Low

385787

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

588809

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695578

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768304

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1106553

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.249

Low

1125120

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

0

High-throughput

0.249

Low

1158767

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1158769

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1158789

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

1158775

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025