Protein: PTH
Peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29)

Gene: PTH, PTRH1
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q86Y79

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0003723 - RNA binding
GO:0004045 - peptidyl-tRNA hydrolase activity
GO:0005739 - mitochondrion
GO:0072344 - rescue of stalled ribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1294780

TIM8B
Mitochondrial import inner membrane translocase subunit Tim8 B

1

1

High-throughput

0.536

High

1294781

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

1

High-throughput

0.536

High

471118

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

1207063

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1294771

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

1281653

ZER1
Protein zer-1 homolog

1

1

High-throughput

0.489

High

1294773

ZY11B
Protein zyg-11 homolog B

1

1

High-throughput

0.489

High

1294775

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

1

High-throughput

0.489

High

1294772

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

401092

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

372481

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

406355

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

920093

PLK1
Serine/threonine-protein kinase PLK1

1

1

High-throughput

0.437

High

653422

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

1145612

RCN1
Reticulocalbin-1

3

0

High-throughput

0.347

High

177254

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

2

0

High-throughput

0.316

High

1009674

NGAL
Neutrophil gelatinase-associated lipocalin

2

0

High-throughput

0.316

High

1294776

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1294770

FAM9B
Protein FAM9B

1

0

High-throughput

0.299

High

396452

ESR1
Estrogen receptor

2

0

High-throughput

0.298

High

718420

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.279

Low

1294774

PIP30
PSME3-interacting protein

1

0

High-throughput

0.279

Low

1294779

MED13
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.279

Low

106216

APRIO
Alternative prion protein

1

0

Small-scale

0.261

Low

404832

PRIO
Major prion protein

1

0

Small-scale

0.261

Low

1095694

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.249

Low

1137828

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.249

Low

1254494

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1294777

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

0

High-throughput

0.249

Low

1294778

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025