Protein: HIPK1
Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)

Gene: HIPK1
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q86Z02

Gene Ontology (top 5):
GO:0001654 - eye development
GO:0004674 - protein serine/threonine kinase activity
GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1295741

RASF5
Ras association domain-containing protein 5

1

8

Small-scale

0.740

High

1116524

FHL3
Four and a half LIM domains protein 3

6

17

High-throughput

0.739

High

414149

P53
Cellular tumor antigen p53

2

14

Small-scale

0.631

High

157577

CTRO
Citron Rho-interacting kinase

1

19

High-throughput

0.618

High

1133946

RB39A
Ras-related protein Rab-39A

1

8

High-throughput

0.618

High

1295739

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.590

High

1295743

PARK7
Parkinson disease protein 7

1

0

Small-scale

0.549

High

303337

PDE9A
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

1

6

High-throughput

0.541

High

540904

ERG
Transcriptional regulator ERG

1

6

High-throughput

0.541

High

578680

GLNA
Glutamine synthetase

1

3

High-throughput

0.541

High

771905

CBS
Cystathionine beta-synthase

1

3

High-throughput

0.541

High

939206

SUMO3
Small ubiquitin-related modifier 3

1

10

High-throughput

0.541

High

993643

UBC9
SUMO-conjugating enzyme UBC9

1

10

High-throughput

0.541

High

1295746

AT132
Polyamine-transporting ATPase 13A2

1

11

Small-scale

0.541

High

1123029

FHL2
Four and a half LIM domains protein 2

1

17

High-throughput

0.536

High

1295744

FOXP3
Forkhead box protein P3

1

6

High-throughput

0.536

High

1295745

SHRPN
Sharpin

1

1

High-throughput

0.536

High

1295749

DAXX
Death domain-associated protein 6

1

3

Small-scale

0.515

High

280706

PR40A
Pre-mRNA-processing factor 40 homolog A

1

8

High-throughput

0.508

High

555505

SKIL
Ski-like protein

1

5

High-throughput

0.508

High

1295748

SENP1
Sentrin-specific protease 1

1

2

Small-scale

0.501

High

124397

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.489

High

1295742

CBP
CREB-binding protein

1

20

Small-scale

0.481

High

143100

NFIB
Nuclear factor 1 B-type

1

5

High-throughput

0.479

High

211576

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

18

Small-scale

0.479

High

474108

NFIC
Nuclear factor 1 C-type

1

8

High-throughput

0.479

High

635539

NEBU
Nebulin

1

10

High-throughput

0.479

High

714244

PML
Protein PML

1

20

High-throughput

0.479

High

1087851

NFIA
Nuclear factor 1 A-type

1

10

High-throughput

0.479

High

1133512

NFIX
Nuclear factor 1 X-type

1

9

High-throughput

0.479

High

1295738

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

15

Small-scale

0.479

High

1295740

DDX54
ATP-dependent RNA helicase DDX54

1

13

High-throughput

0.479

High

1295747

I17RB
Interleukin-17 receptor B

1

0

Small-scale

0.458

High

387435

APOE
Apolipoprotein E

1

2

High-throughput

0.457

High

1059887

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

5

High-throughput

0.457

High

369696

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025