Protein: GLNA
Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase) (Palmitoyltransferase GLUL) (EC 2.3.1.225)

Gene: GLNA, GLUL
Organism: Homo sapiens
Interactions: 144
UniProt ID: P15104

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0004356 - glutamine synthetase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

578626

GLNA
Glutamine synthetase

6

13

Small-scale

0.945

High

578708

TCHP
Trichoplein keratin filament-binding protein

4

0

High-throughput

0.661

High

578715

ASPC1
Tether containing UBX domain for GLUT4

4

0

High-throughput

0.661

High

578739

NDK7
Nucleoside diphosphate kinase homolog 7

4

0

High-throughput

0.661

High

578690

ZFN2B
AN1-type zinc finger protein 2B

3

0

High-throughput

0.638

High

578737

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

3

0

Small-scale

0.636

High

578671

NUD18
8-oxo-dGDP phosphatase NUDT18

2

0

High-throughput

0.582

High

578734

PNMA2
Paraneoplastic antigen Ma2

2

1

High-throughput

0.549

High

578628

ATTY
Tyrosine aminotransferase

1

0

High-throughput

0.549

High

297437

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

High-throughput

0.541

High

297744

PIAS2
E3 SUMO-protein ligase PIAS2

1

2

High-throughput

0.541

High

578650

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.541

High

578677

RABEK
Rab9 effector protein with kelch motifs

1

2

High-throughput

0.541

High

578680

HIPK1
Homeodomain-interacting protein kinase 1

1

3

High-throughput

0.541

High

578718

HIPK3
Homeodomain-interacting protein kinase 3

1

3

High-throughput

0.541

High

578721

PKHF2
Pleckstrin homology domain-containing family F member 2

1

1

High-throughput

0.541

High

578655

EP300
Histone acetyltransferase p300

1

0

Small-scale

0.537

High

578704

CRBN
Protein cereblon

1

0

Small-scale

0.537

High

552109

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.536

High

578631

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

1

High-throughput

0.536

High

578639

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

2

High-throughput

0.536

High

578651

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.536

High

578662

MK06
Mitogen-activated protein kinase 6

1

2

High-throughput

0.536

High

578672

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

1

High-throughput

0.536

High

578712

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.536

High

578716

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

1

High-throughput

0.536

High

578727

STK26
Serine/threonine-protein kinase 26

1

3

High-throughput

0.536

High

578738

RN115
E3 ubiquitin-protein ligase RNF115

1

1

High-throughput

0.536

High

578740

SP16H
FACT complex subunit SPT16

1

1

High-throughput

0.536

High

249090

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.518

High

397722

NU5M
NADH-ubiquinone oxidoreductase chain 5

1

0

High-throughput

0.518

High

578633

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.518

High

578660

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

578691

RSPH1
Radial spoke head 1 homolog

1

0

High-throughput

0.518

High

578701

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

578733

C8AP2
CASP8-associated protein 2

1

0

High-throughput

0.518

High

62899

POTEF
POTE ankyrin domain family member F

1

0

High-throughput

0.513

High

230251

CREB3
Cyclic AMP-responsive element-binding protein 3

1

0

High-throughput

0.513

High

352676

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

578627

HXB6
Homeobox protein Hox-B6

1

0

High-throughput

0.513

High

578629

PYRG1
CTP synthase 1

1

0

High-throughput

0.513

High

578636

CCNC
Cyclin-C

1

0

High-throughput

0.513

High

578640

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

578641

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.513

High

578644

AMPH
Amphiphysin

1

0

High-throughput

0.513

High

578646

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.513

High

578648

SIK1
Serine/threonine-protein kinase SIK1

1

0

High-throughput

0.513

High

578652

SSBP2
Single-stranded DNA-binding protein 2

1

0

High-throughput

0.513

High

578653

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.513

High

578661

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

0

High-throughput

0.513

High

578669

WDR59
GATOR2 complex protein WDR59

1

0

High-throughput

0.513

High

578674

ZN550
Zinc finger protein 550

1

0

High-throughput

0.513

High

578675

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.513

High

578679

BPHL
Serine hydrolase BPHL

1

0

High-throughput

0.513

High

578684

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.513

High

578689

RNH2C
Ribonuclease H2 subunit C

1

0

High-throughput

0.513

High

578693

RBP56
TATA-binding protein-associated factor 2N

1

0

High-throughput

0.513

High

578698

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.513

High

578700

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.513

High

578711

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.513

High

578714

YTHD1
YTH domain-containing family protein 1

1

0

High-throughput

0.513

High

578722

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

578725

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.513

High

578731

PHF11
PHD finger protein 11

1

0

High-throughput

0.513

High

578736

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

578741

PIAS3
E3 SUMO-protein ligase PIAS3

1

2

High-throughput

0.494

High

155071

SOCS2
Suppressor of cytokine signaling 2

1

0

High-throughput

0.493

High

578719

RHOJ
Rho-related GTP-binding protein RhoJ

1

0

Small-scale

0.493

High

555450

SKIL
Ski-like protein

1

0

High-throughput

0.486

High

578676

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

0

High-throughput

0.486

High

240655

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

334988

ARI2
E3 ubiquitin-protein ligase ARIH2

1

1

High-throughput

0.479

High

402509

ALDOA
Fructose-bisphosphate aldolase A

1

1

High-throughput

0.479

High

507491

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

6

High-throughput

0.479

High

578632

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

High-throughput

0.479

High

578647

TERA
Transitional endoplasmic reticulum ATPase

1

1

Small-scale

0.479

High

578656

TADBP
TAR DNA-binding protein 43

1

3

Small-scale

0.479

High

578659

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

2

High-throughput

0.479

High

578670

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

578678

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.479

High

578687

RIN3
Ras and Rab interactor 3

1

1

High-throughput

0.479

High

578692

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

578720

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

578729

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

578654

PPARD
Peroxisome proliferator-activated receptor delta

1

0

High-throughput

0.460

High

578706

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

Small-scale

0.460

High

341515

EYA4
Protein phosphatase EYA4

1

0

High-throughput

0.458

High

362696

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

379855

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

519710

ANDR
Androgen receptor

1

0

High-throughput

0.458

High

532331

CH60
60 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.458

High

550820

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

578630

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

578634

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.458

High

578642

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

578643

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

578645

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

578658

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

578664

UBAP2
Ubiquitin-associated protein 2

1

0

High-throughput

0.458

High

578665

TENS2
Tensin-2

1

0

High-throughput

0.458

High

578667

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

578685

ZNRF1
E3 ubiquitin-protein ligase ZNRF1

1

0

Small-scale

0.458

High

578686

NPL4
Nuclear protein localization protein 4 homolog

1

0

Small-scale

0.458

High

578694

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

Small-scale

0.458

High

578702

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

578703

RANB9
Ran-binding protein 9

1

0

Small-scale

0.458

High

578713

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

578730

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

578635

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

1

High-throughput

0.445

High

578697

MOAP1
Modulator of apoptosis 1

1

1

High-throughput

0.445

High

578732

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

1

High-throughput

0.445

High

431508

AP2A
Transcription factor AP-2-alpha

1

0

High-throughput

0.438

High

578637

5HT2A
5-hydroxytryptamine receptor 2A

1

0

Small-scale

0.438

High

578649

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

0

Small-scale

0.438

High

578696

CHP3
Calcineurin B homologous protein 3

1

0

High-throughput

0.438

High

578723

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

578673

ASXL2
Putative Polycomb group protein ASXL2

1

2

High-throughput

0.437

High

578682

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.437

High

578683

SLX4
Structure-specific endonuclease subunit SLX4

1

1

High-throughput

0.437

High

578717

ASXL3
Putative Polycomb group protein ASXL3

1

3

High-throughput

0.437

High

211474

PAPS1
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

1

0

High-throughput

0.426

High

261074

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

528999

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

578638

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

0

High-throughput

0.426

High

578666

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

578681

NNRD
ATP-dependent

1

0

High-throughput

0.426

High

578699

ASB9
Ankyrin repeat and SOCS box protein 9

1

0

High-throughput

0.426

High

578705

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.426

High

578707

PKP2
Plakophilin-2

1

0

High-throughput

0.426

High

578710

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.426

High

578688

DMXL2
DmX-like protein 2

3

0

High-throughput

0.347

High

578668

CA094
Uncharacterized protein C1orf94

2

0

High-throughput

0.328

High

578724

TB22B
TBC1 domain family member 22B

2

0

High-throughput

0.328

High

578726

CP39A
24-hydroxycholesterol 7-alpha-hydroxylase

1

0

High-throughput

0.282

High

49930

LNP1
Leukemia NUP98 fusion partner 1

1

0

High-throughput

0.279

Low

325274

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

578657

SRSF6
Serine/arginine-rich splicing factor 6

1

0

High-throughput

0.279

Low

578663

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

578695

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.279

Low

578709

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

578728

F135A
Protein FAM135A

1

0

High-throughput

0.279

Low

105257

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

578735

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025