Protein: NADE
Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase)

Gene: NADE, NADSYN1
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q6IA69

Gene Ontology (top 5):
GO:0003952 - NAD+ synthase (glutamine-hydrolyzing) activity
GO:0004359 - glutaminase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1233246

CUTC
Copper homeostasis protein cutC homolog

4

0

High-throughput

0.654

High

1233250

CHIP
E3 ubiquitin-protein ligase CHIP

3

0

High-throughput

0.634

High

1233249

FKBPL
FK506-binding protein-like

2

1

High-throughput

0.611

High

169597

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

1

High-throughput

0.606

High

220256

FRS3
Fibroblast growth factor receptor substrate 3

2

0

High-throughput

0.580

High

1233233

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.580

High

1233239

TFG
Protein TFG

2

0

High-throughput

0.580

High

1233241

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1233236

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

1

High-throughput

0.558

High

725075

HXC8
Homeobox protein Hox-C8

2

1

High-throughput

0.553

High

1233235

TTC9C
Tetratricopeptide repeat protein 9C

2

5

High-throughput

0.549

High

124797

AIP
AH receptor-interacting protein

1

5

High-throughput

0.536

High

1233247

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

1

4

High-throughput

0.536

High

1193605

Q49AR9
ANKS1A protein

1

1

High-throughput

0.515

High

1233242

MY15B
Unconventional myosin-XVB

1

1

High-throughput

0.515

High

1233245

Q9H614
cDNA: FLJ22686 fis, clone HSI10987

1

1

High-throughput

0.515

High

1136230

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.513

High

487429

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.493

High

1233237

THOC2
THO complex subunit 2

1

0

High-throughput

0.493

High

1233240

RENT1
Regulator of nonsense transcripts 1

1

0

High-throughput

0.486

High

1233238

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

1

High-throughput

0.481

High

241998

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

1233232

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

363420

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

414024

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

1114891

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1233248

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1233251

SNX9
Sorting nexin-9

1

0

High-throughput

0.458

High

350473

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

0

High-throughput

0.316

High

694353

CO8A1
Collagen alpha-1(VIII) chain

2

0

High-throughput

0.316

High

1039764

CREB5
Cyclic AMP-responsive element-binding protein 5

2

0

High-throughput

0.316

High

1233234

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.279

Low

1233243

LBHD1
LBH domain-containing protein 1

1

0

High-throughput

0.279

Low

1233244

EMC6
ER membrane protein complex subunit 6

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025