Protein: MCP
Membrane cofactor protein (TLX) (Trophoblast leukocyte common antigen) (CD antigen CD46)

Gene: MCP, CD46
Organism: Homo sapiens
Interactions: 41
UniProt ID: P15529

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0002079 - inner acrosomal membrane
GO:0002250 - adaptive immune response
GO:0002456 - T cell mediated immunity
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

369823

CO3
Complement C3

5

20

Small-scale

0.915

High

584677

JAG1
Protein jagged-1

1

7

Small-scale

0.716

High

501865

CO4B
Complement C4-B

1

20

Small-scale

0.618

High

584664

MCP
Membrane cofactor protein

1

13

Small-scale

0.618

High

584665

ITA2
Integrin alpha-2

1

5

Small-scale

0.618

High

584674

CD81
CD81 antigen

2

4

Small-scale

0.611

High

258630

G37L1
G-protein coupled receptor 37-like 1

2

1

High-throughput

0.606

High

584666

CD9
CD9 antigen

2

4

Small-scale

0.584

High

425240

CFAI
Complement factor I

1

7

Small-scale

0.575

High

584685

ANR46
Ankyrin repeat domain-containing protein 46

2

1

High-throughput

0.553

High

584669

CALX
Calnexin

1

1

High-throughput

0.536

High

584672

STAT3
Signal transducer and activator of transcription 3

1

2

Small-scale

0.515

High

584684

GGYF2
GRB10-interacting GYF protein 2

1

4

High-throughput

0.515

High

584689

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

1

Small-scale

0.506

High

557063

SRC
Proto-oncogene tyrosine-protein kinase Src

1

5

Small-scale

0.501

High

584680

TR16L
Tripartite motif-containing protein 16-like protein

1

1

High-throughput

0.489

High

217786

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

362703

EGFR
Epidermal growth factor receptor

1

8

High-throughput

0.479

High

410583

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

7

High-throughput

0.479

High

431688

ITB1
Integrin beta-1

1

3

Small-scale

0.479

High

462973

YES
Tyrosine-protein kinase Yes

1

6

Small-scale

0.479

High

584667

MOES
Moesin

1

1

Small-scale

0.479

High

584668

CD82
CD82 antigen

1

4

Small-scale

0.479

High

584670

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

5

Small-scale

0.479

High

584671

BASI
Basigin

1

2

High-throughput

0.479

High

584673

CD151
CD151 antigen

1

4

Small-scale

0.479

High

584678

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.479

High

584676

DLG4
Disks large homolog 4

1

0

Small-scale

0.460

High

375146

RASK
GTPase KRas

1

0

High-throughput

0.458

High

584683

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

584687

LAT4
Large neutral amino acids transporter small subunit 4

1

1

High-throughput

0.445

High

584692

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

584686

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

0

High-throughput

0.426

High

584679

PO4F2
POU domain, class 4, transcription factor 2

2

0

High-throughput

0.316

High

584688

AGR3
Anterior gradient protein 3

2

0

High-throughput

0.316

High

584690

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

0

High-throughput

0.316

High

584691

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

0

Small-scale

0.269

Low

584681

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

584675

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

584682

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025