Protein: ATG4A
Cysteine protease ATG4A (EC 3.4.22.-) (AUT-like 2 cysteine endopeptidase) (Autophagy-related cysteine endopeptidase 2) (Autophagin-2) (Autophagy-related protein 4 homolog A) (HsAPG4A) (hAPG4A)

Gene: ATG4A
Organism: Homo sapiens
Interactions: 31
UniProt ID: Q8WYN0

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000423 - mitophagy
GO:0004197 - cysteine-type endopeptidase activity
GO:0005737 - cytoplasm
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1361652

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

3

20

High-throughput

0.871

High

1361651

MLP3B
Microtubule-associated protein 1 light chain 3 beta

3

20

Small-scale

0.844

High

328090

GBRAP
Gamma-aminobutyric acid receptor-associated protein

2

20

Small-scale

0.799

High

952270

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

2

20

Small-scale

0.755

High

1351353

BCAS4
Breast carcinoma-amplified sequence 4

3

0

High-throughput

0.638

High

156393

HSPB6
Heat shock protein beta-6

2

0

High-throughput

0.602

High

1361653

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

20

High-throughput

0.575

High

1309340

CDKL3
Cyclin-dependent kinase-like 3

1

0

High-throughput

0.549

High

507294

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

1

High-throughput

0.536

High

1258258

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

1

High-throughput

0.536

High

1293380

CARM1
Histone-arginine methyltransferase CARM1

1

1

High-throughput

0.536

High

1315512

BD1L2
Biorientation of chromosomes in cell division protein 1-like 2

1

1

High-throughput

0.536

High

1361648

BOD1
Biorientation of chromosomes in cell division protein 1

1

1

High-throughput

0.536

High

1361658

WDR37
WD repeat-containing protein 37

1

1

High-throughput

0.536

High

902213

RAB13
Ras-related protein Rab-13

1

0

High-throughput

0.513

High

1351916

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.513

High

1361647

THOC1
THO complex subunit 1

1

0

High-throughput

0.513

High

1361654

UFSP2
Ufm1-specific protease 2

1

0

High-throughput

0.513

High

1361657

SNX6
Sorting nexin-6

1

0

High-throughput

0.513

High

1361649

ATGA1
Autophagy-related protein 101

1

0

Small-scale

0.460

High

1338870

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.458

High

1248892

LCN15
Lipocalin-15

3

0

High-throughput

0.347

High

1211593

CA220
Putative uncharacterized protein C1orf220

2

0

High-throughput

0.288

High

605524

SYN1
Synapsin-1

1

0

High-throughput

0.279

Low

721517

ILEU
Leukocyte elastase inhibitor

1

0

High-throughput

0.279

Low

1104299

BT1A1
Butyrophilin subfamily 1 member A1

1

0

High-throughput

0.279

Low

1142610

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

1250563

PACS1
Phosphofurin acidic cluster sorting protein 1

1

0

High-throughput

0.279

Low

1361650

NUF2
Kinetochore protein Nuf2

1

0

High-throughput

0.279

Low

1361655

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.279

Low

1361656

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025