Protein: CDKL3
Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)

Gene: CDKL3
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q8IVW4

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1309341

ZBT8A
Zinc finger and BTB domain-containing protein 8A

3

2

High-throughput

0.871

High

212847

ZBT43
Zinc finger and BTB domain-containing protein 43

2

2

High-throughput

0.783

High

1104609

IKZF1
DNA-binding protein Ikaros

2

2

High-throughput

0.783

High

1224996

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

4

High-throughput

0.783

High

1309343

SRPK1
SRSF protein kinase 1

1

16

High-throughput

0.710

High

229343

ZBT14
Zinc finger and BTB domain-containing protein 14

1

0

High-throughput

0.702

High

472872

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

10

High-throughput

0.698

High

900405

FXR2
RNA-binding protein FXR2

4

2

High-throughput

0.698

High

1205865

MTUS2
Microtubule-associated tumor suppressor candidate 2

4

20

High-throughput

0.698

High

1209359

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

12

High-throughput

0.692

High

923360

MK12
Mitogen-activated protein kinase 12

1

19

High-throughput

0.691

High

1025383

CDK6
Cyclin-dependent kinase 6

1

18

High-throughput

0.691

High

1309337

ST32A
Serine/threonine-protein kinase 32A

1

9

High-throughput

0.691

High

572056

TRI27
Zinc finger protein RFP

3

6

High-throughput

0.675

High

340646

STABP
STAM-binding protein

3

0

High-throughput

0.634

High

323474

TRI37
E3 ubiquitin-protein ligase TRIM37

2

12

High-throughput

0.606

High

659526

CRCM
Colorectal mutant cancer protein

2

15

High-throughput

0.606

High

900021

FXR1
RNA-binding protein FXR1

2

2

High-throughput

0.606

High

1309339

PIHD2
PIH1 domain-containing protein 2

2

1

High-throughput

0.606

High

1309351

LR2BP
LRP2-binding protein

2

5

High-throughput

0.606

High

1309352

ZRAN1
Ubiquitin thioesterase ZRANB1

2

7

High-throughput

0.606

High

422515

A4
Amyloid-beta precursor protein

2

6

High-throughput

0.602

High

1309349

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1309345

MDFI
MyoD family inhibitor

1

1

High-throughput

0.573

High

1144845

RABE1
Rab GTPase-binding effector protein 1

2

17

High-throughput

0.553

High

1309340

ATG4A
Cysteine protease ATG4A

1

0

High-throughput

0.549

High

1309348

DAAF6
Dynein axonemal assembly factor 6

1

0

High-throughput

0.549

High

1309354

TTF2
Transcription termination factor 2

1

6

High-throughput

0.541

High

361804

PNPH
Purine nucleoside phosphorylase

1

1

High-throughput

0.536

High

415697

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.536

High

479843

GSTP1
Glutathione S-transferase P

1

2

High-throughput

0.536

High

537469

HSP7C
Heat shock cognate 71 kDa protein

1

15

High-throughput

0.536

High

575161

IDE
Insulin-degrading enzyme

1

1

High-throughput

0.536

High

587727

DESP
Desmoplakin

1

20

High-throughput

0.536

High

713412

SPB3
Serpin B3

1

3

High-throughput

0.536

High

716315

PRDX6
Peroxiredoxin-6

1

12

High-throughput

0.536

High

983526

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

8

High-throughput

0.536

High

984189

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

8

High-throughput

0.536

High

1128529

DSC3
Desmocollin-3

1

8

High-throughput

0.536

High

1309336

LS14A
Protein LSM14 homolog A

1

7

High-throughput

0.536

High

1063404

GOGA2
Golgin subfamily A member 2

1

20

High-throughput

0.523

High

1309335

KASH5
Protein KASH5

1

19

High-throughput

0.523

High

1309346

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.523

High

391044

TRFL
Lactotransferrin

1

0

High-throughput

0.513

High

652351

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.513

High

1309342

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.513

High

1309344

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.513

High

592860

CBR1
Carbonyl reductase [NADPH] 1

1

5

High-throughput

0.489

High

1272455

GDPD3
Lysophospholipase D GDPD3

1

1

High-throughput

0.489

High

1309338

POF1B
Protein POF1B

1

1

High-throughput

0.489

High

996231

EF1A1
Elongation factor 1-alpha 1

1

8

High-throughput

0.479

High

1051797

EF1A2
Elongation factor 1-alpha 2

1

8

High-throughput

0.479

High

1045033

PRB3
Basic salivary proline-rich protein 3

1

4

High-throughput

0.407

High

70334

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

1309350

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.316

High

950822

KR109
Keratin-associated protein 10-9

1

0

High-throughput

0.299

High

1309353

GGA1
ADP-ribosylation factor-binding protein GGA1

1

0

High-throughput

0.282

High

261217

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.279

Low

391798

SMR3B
Submaxillary gland androgen-regulated protein 3B

1

0

High-throughput

0.279

Low

532230

ESTD
S-formylglutathione hydrolase

1

0

High-throughput

0.279

Low

839583

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.279

Low

1159394

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

1309347

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025