Protein: PACS1
Phosphofurin acidic cluster sorting protein 1 (PACS-1)

Gene: PACS1
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q6VY07

Gene Ontology (top 5):
GO:0002260 - lymphocyte homeostasis
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0030137 - COPI-coated vesicle
GO:0034067 - protein localization to Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1250575

WDR37
WD repeat-containing protein 37

4

5

Small-scale

0.702

High

1250571

GGA3
ADP-ribosylation factor-binding protein GGA3

2

1

Small-scale

0.634

High

966494

1433G
14-3-3 protein gamma

2

10

High-throughput

0.601

High

1049449

1433F
14-3-3 protein eta

2

10

High-throughput

0.601

High

995097

CSK2B
Casein kinase II subunit beta

1

0

Small-scale

0.549

High

997806

CSK21
Casein kinase II subunit alpha

1

0

Small-scale

0.537

High

593406

PGFRA
Platelet-derived growth factor receptor alpha

1

1

High-throughput

0.536

High

341969

CEP43
Centrosomal protein 43

1

0

High-throughput

0.493

High

791474

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

843684

HD
Huntingtin

1

0

High-throughput

0.493

High

927365

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

1250566

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

1250567

LEAP2
Liver-expressed antimicrobial peptide 2

1

1

High-throughput

0.489

High

225825

AP1G1
AP-1 complex subunit gamma-1

1

0

Small-scale

0.480

High

548521

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

Small-scale

0.480

High

541557

FGFR1
Fibroblast growth factor receptor 1

1

2

High-throughput

0.479

High

710316

EPHA2
Ephrin type-A receptor 2

1

1

High-throughput

0.479

High

967810

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.479

High

968351

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

1

High-throughput

0.479

High

988460

RAC1
Ras-related C3 botulinum toxin substrate 1

1

1

High-throughput

0.479

High

1015537

RHOG
Rho-related GTP-binding protein RhoG

1

1

High-throughput

0.479

High

1250570

RHOF
Rho-related GTP-binding protein RhoF

1

2

High-throughput

0.479

High

278518

VAMP4
Vesicle-associated membrane protein 4

1

0

Small-scale

0.458

High

375641

RASK
GTPase KRas

1

0

High-throughput

0.458

High

414059

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

463598

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

898487

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

1045425

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1081746

FP100
Fanconi anemia core complex-associated protein 100

1

0

High-throughput

0.458

High

1250564

SORL
Sortilin-related receptor

1

0

Small-scale

0.458

High

106135

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

412127

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

1250559

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1250573

ALK
ALK tyrosine kinase receptor

1

2

High-throughput

0.437

High

529982

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

934765

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

952214

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

0

High-throughput

0.426

High

1250574

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

1250576

SNX24
Sorting nexin-24

2

0

High-throughput

0.328

High

1250568

SGF29
SAGA-associated factor 29

2

0

High-throughput

0.313

High

1148852

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.279

Low

1208297

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

1250560

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

0

High-throughput

0.279

Low

1250562

IQCF1
IQ domain-containing protein F1

1

0

High-throughput

0.279

Low

1250563

ATG4A
Cysteine protease ATG4A

1

0

High-throughput

0.279

Low

1250569

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.279

Low

488812

FURIN
Furin

1

0

Small-scale

0.275

Low

659033

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

0

High-throughput

0.269

Low

47353

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

1096057

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.268

Low

181714

CTDSL
CTD small phosphatase-like protein

1

0

High-throughput

0.249

Low

845690

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.249

Low

1250561

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

1250565

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1250572

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

342598

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025