Protein: TSR3
18S rRNA aminocarboxypropyltransferase (EC 2.5.1.157) (20S S rRNA accumulation protein 3 homolog) (HsTsr3)

Gene: TSR3
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q9UJK0

Gene Ontology (top 5):
GO:0000154 - rRNA modification
GO:0000455 - enzyme-directed rRNA pseudouridine synthesis
GO:0005829 - cytosol
GO:0016740 - transferase activity
GO:0030490 - maturation of SSU-rRNA

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1049051

REL
Proto-oncogene c-Rel

3

1

High-throughput

0.667

High

1429448

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

3

0

High-throughput

0.638

High

1433372

GOLP3
Golgi phosphoprotein 3

3

0

High-throughput

0.638

High

1460604

MTMR7
Phosphatidylinositol-3-phosphate phosphatase MTMR7

3

0

High-throughput

0.634

High

584161

FOSL2
Fos-related antigen 2

4

1

High-throughput

0.630

High

1169434

SAMTR
S-adenosylmethionine sensor upstream of mTORC1

2

0

High-throughput

0.602

High

1340749

TPC2
Two pore channel protein 2

2

0

High-throughput

0.602

High

1380413

RNF34
E3 ubiquitin-protein ligase RNF34

2

0

High-throughput

0.602

High

610500

PRS6A
26S proteasome regulatory subunit 6A

2

0

High-throughput

0.585

High

391517

FRIL
Ferritin light chain

2

0

High-throughput

0.576

High

921063

FOSB
Protein FosB

1

1

High-throughput

0.536

High

191417

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.513

High

518634

RAP2A
Ras-related protein Rap-2a

1

0

High-throughput

0.513

High

664826

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.513

High

694058

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

978388

RHOB
Rho-related GTP-binding protein RhoB

1

0

High-throughput

0.513

High

1110587

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

0

High-throughput

0.513

High

1145427

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.513

High

1405200

MPP8
M-phase phosphoprotein 8

1

0

High-throughput

0.513

High

1034703

MEF2A
Myocyte-specific enhancer factor 2A

1

0

High-throughput

0.493

High

384579

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.480

High

508799

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

1045887

TF65
Transcription factor p65

1

1

High-throughput

0.479

High

1067810

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.479

High

243238

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

905263

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

1138150

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1141350

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.437

High

1348863

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

1

0

High-throughput

0.426

High

58966

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.407

High

1065038

FGL1
Fibrinogen-like protein 1

4

0

High-throughput

0.360

High

230674

PRIC3
Prickle planar cell polarity protein 3

2

0

High-throughput

0.328

High

1451705

OSER1
Oxidative stress-responsive serine-rich protein 1

2

0

High-throughput

0.328

High

1451945

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

2

0

High-throughput

0.318

High

1315630

CFA46
Cilia- and flagella-associated protein 46

2

0

High-throughput

0.313

High

1386843

KCD12
BTB/POZ domain-containing protein KCTD12

2

0

High-throughput

0.313

High

352584

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.279

Low

1005228

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.279

Low

1042098

LMNB2
Lamin-B2

1

0

High-throughput

0.279

Low

1278648

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

1340874

GA2L2
GAS2-like protein 2

1

0

High-throughput

0.279

Low

1361656

ATG4A
Cysteine protease ATG4A

1

0

High-throughput

0.279

Low

1387714

VWCE
von Willebrand factor C and EGF domain-containing protein

1

0

High-throughput

0.279

Low

1453957

RN181
E3 ubiquitin-protein ligase RNF181

1

0

High-throughput

0.279

Low

1459063

CCG5
Voltage-dependent calcium channel gamma-5 subunit

1

0

High-throughput

0.279

Low

522002

H14
Histone H1.4

1

0

High-throughput

0.249

Low

1327255

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1434178

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1208286

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025