Protein: HDAC8
Histone deacetylase 8 (HD8) (EC 3.5.1.98) (Protein deacetylase HDAC8) (EC 3.5.1.-) (Protein decrotonylase HDAC8) (EC 3.5.1.-)

Gene: HDAC8
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q9BY41

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000228 - nuclear chromosome
GO:0004407 - histone deacetylase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

917872

H4
Histone H4

2

13

Small-scale

0.595

High

510038

ERR1
Steroid hormone receptor ERR1

1

20

Small-scale

0.536

High

254933

CPNE3
Copine-3

1

3

High-throughput

0.536

High

313878

SVIL
Supervillin

1

3

High-throughput

0.536

High

858045

NUP98
Nuclear pore complex protein Nup98-Nup96

1

4

High-throughput

0.536

High

1057383

SMC1A
Structural maintenance of chromosomes protein 1A

1

13

High-throughput

0.536

High

1232568

STAG2
Cohesin subunit SA-2

1

2

High-throughput

0.536

High

1316063

MIC19
MICOS complex subunit MIC19

1

1

High-throughput

0.536

High

1316068

SMC3
Structural maintenance of chromosomes protein 3

1

7

High-throughput

0.536

High

439857

NEP
Neprilysin

1

0

High-throughput

0.513

High

1193248

ZSCA2
Zinc finger and SCAN domain-containing protein 2

1

0

High-throughput

0.513

High

1253184

MDM1
Nuclear protein MDM1

1

0

High-throughput

0.513

High

387443

P53
Cellular tumor antigen p53

1

7

Small-scale

0.501

High

568785

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

5

Small-scale

0.501

High

935199

H31
Histone H3.1

1

18

Small-scale

0.501

High

165035

SC16A
Protein transport protein Sec16A

1

9

High-throughput

0.489

High

419041

TPM3
Tropomyosin alpha-3 chain

1

8

High-throughput

0.489

High

932045

TPM4
Tropomyosin alpha-4 chain

1

6

High-throughput

0.489

High

1137105

CROCC
Rootletin

1

20

High-throughput

0.489

High

1316064

ADDG
Gamma-adducin

1

1

High-throughput

0.489

High

254003

MTG16
Protein CBFA2T3

1

9

Small-scale

0.479

High

299463

UBXN7
UBX domain-containing protein 7

1

1

High-throughput

0.479

High

432230

HS90A
Heat shock protein HSP 90-alpha

1

11

Small-scale

0.479

High

556960

CREB1
Cyclic AMP-responsive element-binding protein 1

1

5

Small-scale

0.479

High

714393

HSP74
Heat shock 70 kDa protein 4

1

16

Small-scale

0.479

High

738016

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

8

Small-scale

0.479

High

776809

STAT3
Signal transducer and activator of transcription 3

1

12

Small-scale

0.479

High

896211

UBC12
NEDD8-conjugating enzyme Ubc12

1

7

High-throughput

0.479

High

979351

UBXN1
UBX domain-containing protein 1

1

3

High-throughput

0.479

High

987465

MTG8
Protein CBFA2T1

1

12

Small-scale

0.479

High

1082371

DDB1
DNA damage-binding protein 1

1

9

Small-scale

0.479

High

1086303

H31T
Histone H3.1t

1

18

Small-scale

0.479

High

1200057

EST1A
Telomerase-binding protein EST1A

1

2

Small-scale

0.479

High

1316065

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1316066

XPO7
Exportin-7

1

6

High-throughput

0.479

High

1316067

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

2

Small-scale

0.479

High

1316069

DCAF1
DDB1- and CUL4-associated factor 1

1

9

Small-scale

0.479

High

933046

ACTS
Actin, alpha skeletal muscle

1

7

Small-scale

0.437

High

1296892

SNX27
Sorting nexin-27

1

6

High-throughput

0.437

High

1056969

MDC1
Mediator of DNA damage checkpoint protein 1

1

12

Small-scale

0.408

High

1087792

RTN1
Reticulon-1

1

0

Small-scale

0.261

Low


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Last updated: 15 Jul 2024