Protein: RO60
RNA-binding protein RO60 (60 kDa SS-A/Ro ribonucleoprotein) (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Ro60 autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2)

Gene: RO60
Organism: Homo sapiens
Interactions: 73
UniProt ID: P10155

Gene Ontology (top 5):
GO:0002520 - immune system development
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005929 - cilium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

430966

LA
Lupus La protein

3

1

Small-scale

0.675

High

518978

ELAV2
ELAV-like protein 2

3

0

High-throughput

0.634

High

519008

PUF60
Poly(U)-binding-splicing factor PUF60

2

1

High-throughput

0.621

High

518982

NBR1
Next to BRCA1 gene 1 protein

2

0

Small-scale

0.585

High

518985

LARP7
La-related protein 7

2

1

High-throughput

0.584

High

518975

SRSF3
Serine/arginine-rich splicing factor 3

2

0

High-throughput

0.576

High

240566

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

518962

U2AF2
Splicing factor U2AF 65 kDa subunit

1

2

High-throughput

0.536

High

519007

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

1

High-throughput

0.536

High

518987

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.528

High

518977

VIGLN
Vigilin

1

2

High-throughput

0.515

High

446578

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

518958

SRF
Serum response factor

1

0

High-throughput

0.513

High

518973

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

518974

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.513

High

518980

CUL3
Cullin-3

1

0

High-throughput

0.513

High

518996

IFTAP
Intraflagellar transport-associated protein

1

0

High-throughput

0.513

High

185376

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

518961

DDX6
Probable ATP-dependent RNA helicase DDX6

1

0

Small-scale

0.480

High

518971

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

371008

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

405720

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

518966

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

518976

RBM3
RNA-binding protein 3

1

1

Small-scale

0.479

High

519012

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

1

High-throughput

0.479

High

156880

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

339315

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.458

High

349754

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

472419

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

518959

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

518963

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

518964

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

518965

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

518967

MATR3
Matrin-3

1

0

High-throughput

0.458

High

518968

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

518969

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

518972

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

518979

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

518983

FSCN1
Fascin

1

0

High-throughput

0.458

High

518984

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

518986

MIDN
Midnolin

1

0

High-throughput

0.458

High

518988

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

518990

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

518994

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

518999

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.458

High

519000

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

519002

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

519004

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

519005

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

519006

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

519009

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

519011

DUS12
Dual specificity protein phosphatase 12

1

0

High-throughput

0.458

High

327754

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

High-throughput

0.445

High

518970

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

High-throughput

0.445

High

518989

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

1

Small-scale

0.445

High

519001

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

2

High-throughput

0.445

High

518993

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

519003

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

400176

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.426

High

429188

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

518956

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

518960

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

Small-scale

0.426

High

518981

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

518991

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

519010

LORF1
LINE-1 retrotransposable element ORF1 protein

1

0

Small-scale

0.426

High

293101

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

302737

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.249

Low

411242

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

518992

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

518995

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

518997

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

518998

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

518957

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025