Protein: SPA12
Serpin A12 (OL-64) (Visceral adipose tissue-derived serine protease inhibitor) (Vaspin) (Visceral adipose-specific serpin)

Gene: SPA12, SERPINA12
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q8IW75

Gene Ontology (top 5):
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006094 - gluconeogenesis
GO:0008610 - lipid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

258324

LRP5
Low-density lipoprotein receptor-related protein 5

2

1

High-throughput

0.811

High

1218290

NECT2
Nectin-2

2

1

High-throughput

0.811

High

1218311

TM11E
Transmembrane protease serine 11E

1

20

High-throughput

0.691

High

1060404

KI3S1
Killer cell immunoglobulin-like receptor 3DS1

3

6

High-throughput

0.667

High

433171

LAMB1
Laminin subunit beta-1

2

1

High-throughput

0.628

High

548731

VAV
Proto-oncogene vav

2

1

High-throughput

0.628

High

566891

ITA2
Integrin alpha-2

2

5

High-throughput

0.628

High

1041080

CUL1
Cullin-1

2

6

High-throughput

0.628

High

1166442

SE6L2
Seizure 6-like protein 2

2

3

High-throughput

0.628

High

1218302

K1549
UPF0606 protein KIAA1549

2

1

High-throughput

0.628

High

883423

CF298
Cilia- and flagella-associated protein 298

3

4

High-throughput

0.609

High

1206145

PLCZ1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

3

1

High-throughput

0.609

High

1218293

GMCL1
Germ cell-less protein-like 1

3

1

High-throughput

0.609

High

1218298

SC22C
Vesicle-trafficking protein SEC22c

3

1

High-throughput

0.609

High

1218306

PLK2
Serine/threonine-protein kinase PLK2

3

3

High-throughput

0.609

High

617125

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

2

0

High-throughput

0.602

High

1218287

AGRV1
Adhesion G-protein coupled receptor V1

2

0

High-throughput

0.602

High

1218308

TEN3
Teneurin-3

2

0

High-throughput

0.602

High

209341

TSN6
Tetraspanin-6

2

5

High-throughput

0.574

High

297520

TOX4
TOX high mobility group box family member 4

2

11

High-throughput

0.574

High

365210

FRIH
Ferritin heavy chain

2

4

High-throughput

0.574

High

1069739

NONO
Non-POU domain-containing octamer-binding protein

2

3

High-throughput

0.574

High

1127258

TGO1
Transport and Golgi organization protein 1 homolog

2

8

High-throughput

0.574

High

1218277

WDR75
WD repeat-containing protein 75

2

4

High-throughput

0.574

High

1218294

TXD15
Thioredoxin domain-containing protein 15

2

3

High-throughput

0.574

High

1218305

RFOX1
RNA binding protein fox-1 homolog 1

2

1

High-throughput

0.574

High

1218314

FCF1
rRNA-processing protein FCF1 homolog

2

3

High-throughput

0.574

High

174409

FANCG
Fanconi anemia group G protein

1

2

High-throughput

0.536

High

275051

RENR
Renin receptor

1

6

High-throughput

0.536

High

392935

IFNA4
Interferon alpha-4

1

2

High-throughput

0.536

High

676752

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

1

High-throughput

0.536

High

713396

CD68
Macrosialin

1

1

High-throughput

0.536

High

882766

STX17
Syntaxin-17

1

9

High-throughput

0.536

High

1218281

EHBP1
EH domain-binding protein 1

1

1

High-throughput

0.536

High

1218283

MYBPP
MYCBP-associated protein

1

1

High-throughput

0.536

High

1016618

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.513

High

1218278

K319L
Dyslexia-associated protein KIAA0319-like protein

1

0

High-throughput

0.513

High

1218282

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.513

High

200833

ZSC12
Zinc finger and SCAN domain-containing protein 12

2

1

High-throughput

0.504

High

206914

CHSTA
Carbohydrate sulfotransferase 10

1

4

High-throughput

0.489

High

217577

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

2

High-throughput

0.489

High

237670

SEP15
Selenoprotein F

1

4

High-throughput

0.489

High

580367

TSN8
Tetraspanin-8

1

5

High-throughput

0.489

High

599687

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

4

High-throughput

0.489

High

624464

CCNC
Cyclin-C

1

6

High-throughput

0.489

High

921135

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

5

High-throughput

0.489

High

974493

ENL
Protein ENL

1

1

High-throughput

0.489

High

1024309

ZN154
Zinc finger protein 154

1

2

High-throughput

0.489

High

1060275

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

1

1

High-throughput

0.489

High

1119410

VWA3B
von Willebrand factor A domain-containing protein 3B

1

1

High-throughput

0.489

High

1124867

LRC10
Leucine-rich repeat-containing protein 10

1

3

High-throughput

0.489

High

1201375

MOGT3
2-acylglycerol O-acyltransferase 3

1

7

High-throughput

0.489

High

1203079

ZC3C1
Zinc finger C3HC-type protein 1

1

4

High-throughput

0.489

High

1203660

AROS
Active regulator of SIRT1

1

2

High-throughput

0.489

High

1204487

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

2

High-throughput

0.489

High

1216873

EPHX4
Epoxide hydrolase 4

1

3

High-throughput

0.489

High

1218285

TRI41
E3 ubiquitin-protein ligase TRIM41

1

2

High-throughput

0.489

High

1218286

ZDH19
Palmitoyltransferase ZDHHC19

1

3

High-throughput

0.489

High

1218288

THAP4
Peroxynitrite isomerase THAP4

1

3

High-throughput

0.489

High

1218289

SIA8A
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase

1

3

High-throughput

0.489

High

1218291

SARAF
Store-operated calcium entry-associated regulatory factor

1

9

High-throughput

0.489

High

1218296

TEFM
Transcription elongation factor, mitochondrial

1

4

High-throughput

0.489

High

1218301

HES4
Transcription factor HES-4

1

4

High-throughput

0.489

High

1218303

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

1

High-throughput

0.489

High

1218304

TSSP
Thymus-specific serine protease

1

5

High-throughput

0.489

High

1218307

DTL
Denticleless protein homolog

1

4

High-throughput

0.489

High

1218309

HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2

1

4

High-throughput

0.489

High

1218310

PCOC2
Procollagen C-endopeptidase enhancer 2

1

1

High-throughput

0.489

High

1218312

PHF8
Histone lysine demethylase PHF8

1

3

High-throughput

0.489

High

1218313

FOXJ3
Forkhead box protein J3

1

4

High-throughput

0.489

High

504360

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

1117763

Q4LE69
1-phosphatidylinositol 4-kinase

1

11

High-throughput

0.479

High

1218297

RANB9
Ran-binding protein 9

1

5

Small-scale

0.479

High

957732

XIAP
E3 ubiquitin-protein ligase XIAP

1

4

High-throughput

0.457

High

787662

PI4KA
Phosphatidylinositol 4-kinase alpha

1

11

High-throughput

0.445

High

818224

SOX2
Transcription factor SOX-2

1

12

High-throughput

0.437

High

1218299

FACD2
Fanconi anemia group D2 protein

1

12

High-throughput

0.437

High

1218279

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

11

High-throughput

0.407

High

1218295

MIA2
Melanoma inhibitory activity protein 2

1

8

High-throughput

0.407

High

236535

CIDEA
Lipid transferase CIDEA

3

0

High-throughput

0.347

High

1115540

GLYR1
Cytokine-like nuclear factor N-PAC

3

0

High-throughput

0.347

High

1159372

DEN1B
DENN domain-containing protein 1B

3

0

High-throughput

0.342

High

229771

SUSD5
Sushi domain-containing protein 5

2

0

High-throughput

0.328

High

1218284

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

2

0

High-throughput

0.328

High

1156626

TECT3
Tectonic-3

2

0

High-throughput

0.318

High

265676

E2F6
Transcription factor E2F6

1

0

High-throughput

0.279

Low

885933

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.279

Low

1051602

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.279

Low

1125937

BEX5
Protein BEX5

1

0

High-throughput

0.279

Low

1136905

AHDC1
Transcription factor Gibbin

1

0

High-throughput

0.279

Low

1138799

SPO16
Protein SPO16 homolog

1

0

High-throughput

0.279

Low

1165253

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

1

0

High-throughput

0.279

Low

1169849

CFA77
Cilia- and flagella-associated protein 77

1

0

High-throughput

0.279

Low

1218292

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.279

Low

1218300

CEP15
Centrosomal protein 15

1

0

High-throughput

0.269

Low

212458

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

0

High-throughput

0.249

Low

666405

3MG
DNA-3-methyladenine glycosylase

1

0

Small-scale

0.249

Low

1051730

RCAN2
Calcipressin-2

1

0

High-throughput

0.249

Low

1218280

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024